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BYOMA Clarifying Serum for acne-prone skin

High

  • HighCombination Skin Fit
  • HighEffectiveness
  • HighSafety

A great choice for acne-prone skin; a few serums fit it even better.

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers excellent pore-clearing and skin-texture smoothing for your combination, acne-prone skin due to the presence of niacinamide and gluconolactone, which help regulate oil production and refine pores.
  • The formulation is highly suitable for combination skin, with niacinamide providing seboregulation and gluconolactone offering mild exfoliation to support blemish control.
  • The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients.

How to apply

  • Use your serum as part of your PM routine and start 3x/week before working up to daily use.
  • Apply this treatment after cleansing and toner, and before your moisturizer.
  • Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
  • Apply the product on clean, dry skin to help manage your breakouts safely.
  • Avoid the eye area and do a patch test before your first use.

People Say

★4.4Overall rating based on 1.3k+ reviews

Based on a very large amount of data, users with oily, acne-prone, and sensitive skin frequently praise this serum for its ability to clear breakouts and reduce redness without stripping the skin barrier. Many report smoother texture and unclogged pores, while a minority of reviewers found the formula sticky or ineffective for their specific skin concerns.

Highlights

  • Clears acne Mostly Mentioned
    • “breakouts are nearly non existent”
    • “gotten rid of the annoying bumps”
    • “cleared up so much of my acne”
    • “stops congestion”
  • Gentle and soothing Often Mentioned
    • “gentle-yet-effective”
    • “no reaction at all”
    • “calm inflammation”
    • “doesn't strip my skin”
  • Great value Sometimes Noted
    • “affordable”
    • “price is freaking good”
    • “good value products”
    • “great price compared to others”
  • Hydrating formula Sometimes Noted
    • “hydrating for the price”
    • “skin feels plump”
    • “doesn't feel heavy”
    • “moisturized without grease”
  • Improves texture Sometimes Noted
    • “skin is lots smoother”
    • “pores have shrunk”
    • “reduced appearance of blackheads”
    • “texture is better”
  • Sticky texture Sometimes Noted
    • “A little bit sticky”
    • “feels sticky”
    • “tacky residue”
    • “takes time to absorb”
  • Caused breakouts Rarely Noted
    • “broke out from using them”
    • “skin broken out”
    • “caused more pimples”
    • “bad reaction”
  • No visible results Rarely Noted
    • “Did nothing”
    • “didn't notice much of a difference”
    • “acne stayed”
    • “pores looked the same”
  • Packaging issues Rarely Noted
    • “pump doesn't dispense a lot”
    • “hard to dispense”
    • “can't see how much is left”
    • “pump broke”

Sources: lovi.care, ulta.com, boots.com, spacenk.com, sephora.com, byoma.com, and more

Questions and answers

What makes BYOMA Clarifying Serum a great fit for acne-prone skin?

BYOMA Clarifying Serum is a great fit because it offers excellent pore-clearing and skin-texture smoothing for your acne-prone skin using niacinamide and gluconolactone, which help regulate oil production and refine pores. The formulation is highly suitable by providing seboregulation and mild exfoliation to support blemish control, with an excellent safety profile that is unlikely to cause irritation.

The Australasian Journal of Dermatology, 1992Clinical, Cosmetic and Investigational Dermatology, 2019

Which ingredients make this serum a good fit for acne-prone skin?

This serum is a great fit for your acne-prone skin because niacinamide and gluconolactone help clear pores, balance oil production, and smooth your skin texture. These ingredients work together to support blemish control safely while keeping your skin calm and comfortable.

The Australasian Journal of Dermatology, 1992Skin Research and Technology, 2023

What do Ceramides do for acne-prone skin?

Ceramides help acne-prone skin by restoring a damaged water barrier, which reduces dryness, redness, and flaking caused by harsh acne treatments. Using ceramides also may lower inflammation and improve overall skin comfort while keeping breakouts in check.

Journal of Drugs in Dermatology, 2023Journal of Cosmetic Dermatology, 2024

What does Blue Tansy do for acne-prone skin?

Blue Tansy helps calm red, angry blemishes and soothes irritated skin. Its natural properties help keep pores clear and balance oily areas, making it a great addition to your routine.

Where does it go in a skincare routine for acne-prone skin?

This treatment goes in your evening routine, applied after cleansing and before your moisturizer. Using it at night keeps things simple and provides extra safety around sun exposure.

Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying it in your morning routine or on alternating nights to keep your skin calm and clear. Using soothing ingredients like niacinamide and ceramides alongside your routine helps prevent irritation while supporting blemish control.

Journal of Cosmetic Dermatology, 2024American Family Physician, 2012

How often should I use it?

You can use this treatment in your evening routine, starting once a week and slowly using it more often if your skin tolerates it well. Niacinamide and gluconolactone help clear pores and smooth your skin while keeping irritation unlikely.

The Australasian Journal of Dermatology, 1992

Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is a great fit for your acne-prone skin because it uses niacinamide and gluconolactone to clear pores and smooth texture without harsh ingredients that cause irritation. It is unlikely to clog pores or cause breakouts, and reviews show that bad reactions are rare.

The Australasian Journal of Dermatology, 1992Clinical, Cosmetic and Investigational Dermatology, 2019

Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients.

    The Australasian Journal of Dermatology, 1992
  • Combining 10% gluconolactone chemical peeling with oxybrasion or microneedle mesotherapy increased skin hydration and decreased sebum, pH, and TEWL in twenty-one Caucasian women, with no significant differences between the two methods.

    Skin Research and Technology, 2023
  • Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris.

    Clinical, Cosmetic and Investigational Dermatology, 2019
  • Topical application of a ceramide complex cream significantly ameliorated lactic acid sensations and increased stratum corneum total ceramide content in 39 female subjects with sensitive skin compared with placebo.

    Archives of Dermatological Research, 2018
  • A canine-specific ceramide complex consisting of a 4:1 ratio of CER [NS] to [EOP] reduced proinflammatory cytokine expression, upregulated skin barrier-related genes and enzymes, improved stratum corneum organization, and accelerated skin barrier repair in vitro and in vivo.

    Animals, 2026
  • Topical chamazulene treatment mitigates UVB-induced photoaging in mouse skin by upregulating fatty acid metabolism genes, restoring fatty acid homeostasis, enhancing non-essential amino acid metabolism, and downregulating the p38 MAPK/COX-2 pathway, likely via PPARα/γ activation.

    Antioxidants, 2025
  • Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

    Journal of Cosmetic Dermatology, 2021
  • Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

    The Journal of Investigative Dermatology, 2008
  • Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

    Dermatologic Surgery, 2005
  • Topical zinc treatment enhanced MMP-1 expression beneath the neoepidermis and metallothionein expression under the neoepidermis and in the wound bed in human epidermal wounds compared to placebo and control treatments.

    European Journal of Cell Biology, 2021
  • Topical preparations containing zinc(II) complexes with glycine and histidine effectively treat acne skin by providing high antibacterial activity against C. acnes and low cytotoxicity for skin cells, with no observed irritation or allergy in healthy volunteers.

    International Journal of Molecular Sciences, 2021
  • Topical copper and zinc formulations promote skin healing by exerting antimicrobial effects, modulating macrophage polarization, acting as enzyme cofactors, stimulating angiogenesis, and supporting re-epithelialization.

    Dermatology and Therapy, 2026
  • Gluconolactone and tartaric acid significantly lower transepidermal water loss and erythema after sodium lauryl sulphate challenge compared to vehicle, untreated control, and glycolic acid in healthy subjects.

    The British Journal of Dermatology, 1997
  • A polyhydroxy acid skin care regimen provided antiaging benefits comparable to an alpha-hydroxyacid regimen while demonstrating enhanced mildness and better tolerance in subjects.

    Cutis, 2004
  • Gluconolactone treatment significantly increased facial skin hydration in 16 healthy women, with no significant differences between 10% and 30% solutions.

    Skin Research and Technology, 2021

Ingredients

Water, Glycerin, Niacinamide, 1,2-Hexanediol, Polyglyceryl-10 Laurate, Gluconolactone, Glyceryl Caprylate, Ceramide Np, Cholesterol, Caprylic Capric Triglyceride, Phytosphingosine, Stearic Acid, Oleic Acid, Zinc Lactate, Hydrogenated Lecithin, Ethylhexylglycerin, Sodium Hyaluronate, Tanacetum Annuum Oil Flower, Hydroxyethylcellulose, Ammonium Acryloyldimethyltaurate Vp Copolymer, Glyceryl Acrylate Acrylic Acid Copolymer, Sodium Phytate, Tocopherol, Lactic Acid, Caprylyl Glycol, Caprylhydroxamic Acid

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

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