Purito Deep Sea Pure Water Cream for skin with dark spots

How to apply

Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

  American Journal of Clinical Dermatology, 2002

• A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.

  The Journal of Dermatological Treatment, 2017

• Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.

  Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016

• Topical application of Dead Sea water encouraged the expression of barrier-related proteins, increased skin secretion of β-endorphin, and attenuated the expression of inflammatory and irritation-related cytokines in in vitro skin equivalents and ex vivo human skin organ culture.

  Experimental Dermatology, 2019

• Dead Sea water treatment promoted procollagen-1 and elastin secretion, hemidesmosome increase, and epidermal basal cell regeneration in human dermal cells and reconstructed skin models, while activating pathways related to extracellular matrix biosynthesis, DNA repair, and autophagy under normal and UV stress conditions.

  International Journal of Cosmetic Science, 2024

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.

  Arzneimittel-Forschung, 2000

• Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.

  Auris, Nasus, Larynx, 2020

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Phlorotannins isolated from Ecklonia cava inhibit melanogenesis and protect against UV-B-induced photo-oxidative stress in fibroblasts, with dieckol showing the strongest effects.

  Toxicology in Vitro, 2009

• Ecklonia cava extract and dieckol alleviate airborne PM10-induced PGE2 production in HaCaT keratinocytes through the inhibition of gene expression of COX-1, COX-2, mPGES-1, and/or mPGES-2.

  Antioxidants, 2019

• Ecklonia cava extract and its constituents dieckol and eckol attenuated cellular lipid peroxidation and inflammatory cytokine expression in keratinocytes exposed to PM10 compared to PM10 alone.

  Evidence-based Complementary and Alternative Medicine, 2018

Ingredients

Sea Water, Dipropylene Glycol, Glycerin, Caprylic Capric Triglyceride, Sodium Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Polysorbate 80, Sorbitan Oleate, Niacinamide, Phenyl Trimethicone, Cetyl Ethylhexanoate, Cetearyl Alcohol, Water, 1,2-Hexanediol, Butylene Glycol, Sodium Hyaluronate, Panthenol, Ecklonia Cava Extract, Laminaria Japonica Extract, Caulerpa Lentillifera Extract, Salicornia Herbacea Extract, Allantoin, Macadamia Ternifolia Seed Oil, Adenosine, Sorbitan Stearate, Glyceryl Stearate, Carbomer, Arginine, Caprylyl Glycol, Ethylhexylglycerin, Disodium Edta

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.