Shiseido Clarifying Cleansing Foam for sensitive skin

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Questions and answers

What the research says

• Isosecotanapartholide (ISTP) isolated from Artemisia princeps Pampanini extract downregulated STAT-1 expression, reduced IL-33 production, and inhibited TARC/CCL17 mRNA and ICAM-1 protein expression in human keratinocytes stimulated by tumor necrosis factor-alpha/interferon-gamma.

  Molecular Medicine Reports, 2017

• Myristic acid reduced inflammation and nociception by increasing IL-10 production in LPS-stimulated macrophages, reducing acute and chronic TPA-induced ear edema in mice, and involving the nitrergic system in formalin-induced paw licking.

  Journal of Food Biochemistry, 2022

• Babassu oil and lauric acid inhibited mice ear edema induced by various phlogistic agents, and its topical anti-inflammatory activity was markedly increased when formulated into a microemulsion.

  Evidence-based Complementary and Alternative Medicine, 2017

• A bacterial nanocellulose wound dressing incorporating polyhexamethylene biguanide and sericin showed no skin irritation in healthy volunteers and significantly promoted wound healing with lower wound size and higher collagen formation in full-thickness rat wounds compared to controls.

  Archives of Dermatological Research, 2016

• Silk fibroin-based dressings offer exceptional characteristics, biocompatibility, and drug delivery capabilities for skin regeneration and wound healing.

  Trends in Biotechnology, 2018

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• The cytotoxic effect of sodium lauryl sulphate on normal human keratinocytes was significantly decreased when combined with cocamidopropyl betaine, Tween 20, and Tween 80 at concentrations well below the critical micelle concentration.

  Skin Pharmacology and Applied Skin Physiology, 2003

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical application of sericin gels increased skin intrinsic moisturization, hydroxyproline content, and epidermal hydration while decreasing transepidermal water loss and skin impedance in healthy human volunteers.

  Journal of Cosmetic Dermatology, 2005

• Silk fibroin wound dressings exhibit anti-inflammatory and pro-angiogenic properties that accelerate skin wound healing compared to commercially available dressings in preclinical and clinical settings.

  Biomolecules, 2022

• Silk sericin-releasing bacterial nanocellulose gel demonstrated improved mechanical properties, controlled sericin release, non-cytotoxicity on L929 and HaCaT cells, and non-irritancy in subcutaneous tissue compared to a commercially available paper mask.

  BMC Biotechnology, 2014

Ingredients

Water, Stearic Acid, Peg-8, Myristic Acid, Glycerin, Potassium Hydroxide, Dipropylene Glycol, Lauric Acid, Glyceryl Stearate Se, Sorbitol, Cocamidopropyl Betaine, Peg-60 Glyceryl Isostearate, Sodium Methyl Cocoyl Taurate, Phytosteryl Macadamiate, Parfum, Polyquaternium-39, Disodium Edta, Rice Germ Oil, Linalool, Geraniol, Citronellol, Kaolin, Sodium Benzoate, Butylene Glycol, Acrylates Copolymer, Betaine, Silk Powder Serica Poudre De Soie Powder, Tocopherol, Sodium Acetylated Hyaluronate, Artemisia Princeps Leaf Extract, Sodium Lauryl Sulfate

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.