Vitamin E

What to combine vitamin E with

Ingredient	Together	How to use them
Glycolic acid	Works well	Use glycolic acid first, followed by vitamin E, because antioxidants help protect freshly exfoliated skin from damage. Vitamin E and glycolic acid
Vitamin C	Works well	Use them together in the morning, applying vitamin C first and vitamin E right after, because they boost each other's sun-protecting power. Vitamin E and vitamin C
Retinol	Works well	Use them together by applying Vitamin E first and Retinol second, because antioxidants help stabilize retinol on the skin. Vitamin E and retinol
AHA blend glycolic and citric acids	Works well	Use them in the same routine, applying the vitamin E after the AHA blend has fully absorbed, because antioxidants protect freshly exfoliated skin. Vitamin E and aha blend glycolic and citric acids
Niacinamide	Works well	Use them together in your morning routine by applying your niacinamide first and vitamin E right after, because they boost each other's sun-protecting power. Vitamin E and niacinamide
Salicylic acid	Works well	Apply salicylic acid first, and follow it with vitamin E, because antioxidants help protect freshly exfoliated skin. Vitamin E and salicylic acid
Bio-placenta peptides	Works well	Use them together in the same routine, applying the antioxidant vitamin E first and the bio-placenta peptides right after. Vitamin E and bio-placenta peptides
Hexapeptide	Works well	Use them together in the same routine, applying the vitamin E product first and the hexapeptide product second, because they help each other work better. Vitamin E and hexapeptide
Lactic acid	Works well	Use lactic acid first, then vitamin E a little later, because antioxidants help protect freshly exfoliated skin. Vitamin E and lactic acid
Acetyl hexapeptide-3	Works well	Use them together in the same routine, applying the peptide first and the vitamin E right after, because vitamin E keeps peptides fresh and strong. Vitamin E and acetyl hexapeptide-3
Mandelic acid	Works well	Use them in the same routine by applying mandelic acid first and vitamin E right after, because antioxidants protect freshly exfoliated skin. Vitamin E and mandelic acid
Hyaluronic acid	Works well	Use them together by applying hyaluronic acid first for hydration, followed by vitamin E to lock in moisture and protect the skin. Vitamin E and hyaluronic acid
Collagen peptide	Works well	Use them together by applying your peptide product first and your vitamin E product right after, because they help each other stay stable. Vitamin E and collagen peptide
Copper peptide	Works well	Use them together in the same routine, applying the antioxidant first to help stabilize the peptide. Vitamin E and copper peptide
Citric acid	Works well	Use them in the same routine by applying vitamin E after citric acid, because antioxidants help protect skin right after exfoliation. Vitamin E and citric acid
Hexapeptide-9	Works well	Use them together in the same routine, applying the vitamin E first and the hexapeptide-9 right after, because they help each other work better. Vitamin E and hexapeptide-9
Peptide-rich plasma	Works well	Use them together by applying the vitamin E product before the peptide plasma, as they help each other fight skin aging. Vitamin E and peptide-rich plasma
Tri-ceramide complex	Works well	Use them together by applying the vitamin E product before the tri-ceramide complex, because antioxidants help keep the ceramide protective layer fresh. Vitamin E and tri-ceramide complex
Triple peptide blend	Works well	Use them together in the same routine, applying the peptide serum first and the vitamin E product right after, because they boost each other's anti-aging effects. Vitamin E and triple peptide blend
Palmitoyl pentapeptide-4	Works well	Use them together in the same routine by applying the antioxidant vitamin E first, followed by the peptide. Vitamin E and palmitoyl pentapeptide-4
Palmitoyl tripeptide-1	Works well	Use them together by applying vitamin E first, because antioxidants stabilize peptides to boost anti-aging results. Vitamin E and palmitoyl tripeptide-1

From the ingredient rules behind the "Works well with" and "Don't mix with" notes on every product in the Lovi app.

Questions and answers

Research on vitamin E

• Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial

  Vitamin E · Journal of Cosmetic Dermatology, 2020

• Topical alpha-tocotrienol supplementation inhibits lipid peroxidation but fails to mitigate increased transepidermal water loss after benzoyl peroxide treatment of human skin

  Vitamin E · Free Radical Biology & Medicine, 2003

• Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects

  Vitamin E · Journal of Cosmetic Dermatology, 2020

• Tocotrienol-rich fraction attenuates UV-induced inflammaging: A bench to bedside study

  Vitamin E · Journal of Cosmetic Dermatology, 2018

• Clinical evaluation of photoprotective effect by a topical antioxidants combination (tocopherols and tocotrienols)

  Vitamin E · Journal of the European Academy of Dermatology and Venereology, 2012

• Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs

  Vitamin E · Journal of Cosmetic Dermatology, 2022

• Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations

  Vitamin E · Journal of Cosmetic Dermatology, 2022

• Influence of vitamin E acetate on stratum corneum hydration

  Vitamin E · Arzneimittel-Forschung, 1998

• Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin

  Vitamin E · Journal of Cosmetic Dermatology, 2024

• Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy

  Vitamin E · Scientific Reports, 2025

• Sustained effect of two antioxidants (oxothiazolidine and δ-tocopheryl glucoside) for immediate and long-term sun protection in a sunscreen emulsion based on their different penetrating properties

  Vitamin E · International Journal of Cosmetic Science, 2021

• Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial

  Vitamin E · Contemporary Clinical Trials Communications, 2021

Behind this ingredient guide

Lovi checks every ingredient with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.