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Shiseido vs Sesderma

Shiseido and Sesderma are distinguished skincare brands originating from Japan and Spain, respectively. The Japanese house is beloved for its thoughtful array of moisturizers, cleansers, sunscreens, and serums formulated with key ingredients like glycerin, while the Spanish enterprise is known for advanced serums and meticulously engineered formulas featuring botanical extracts and active compounds. Both options suit sensitive skin best, with the former also favoring mature skin and the latter accommodating hyperpigmented and aging skin types. They differ primarily in their heritage and specific active approaches, with standout choices ranging from the Treatment Softener and Benefiance Wrinkle Smoothing Day Cream to the Azelac RU Serum.

Shiseido is a Japanese skincare brand founded in 1872 and owned by Shiseido Company, Limited.

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Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

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This page compares some of the most popular Shiseido and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Questions and answers

Shiseido or Sesderma: which is better?

Shiseido is often better suited for dry or mature skin, where Lovi rates several of its moisturizers and sunscreens as High or Superior, while Sesderma offers fewer options on this page. Topical hyaluronic acid, featured in Shiseido's line, helps improve skin quality and signs of aging.

Dermatologic Therapy, 2022

What is the difference between Shiseido and Sesderma?

Shiseido is a Japanese brand founded in 1872 with a wide variety of skincare products on this page, whereas Sesderma is a Spanish brand founded in 1989 with only one product listed. Shiseido fits sensitive and mature skin best, while the products on this page help provide deep hydration and improve radiance.

Which is more affordable, Shiseido or Sesderma?

Reviewers note that Shiseido products on this page have a high price point. The page facts do not mention pricing information for Sesderma.

Which causes fewer breakouts, Shiseido or Sesderma?

Shiseido includes products on this page that achieve a High Lovi fit for acne-prone skin, such as the Essential Energy Hydrating Day Cream, whereas Sesderma offers Azelac RU Serum which also rates High for acne-prone skin.

How does the founding year and country of origin compare between Shiseido and Sesderma?

Shiseido was founded in 1872 in Japan, whereas Sesderma was founded later in 1989 in Spain.

Which brand offers a greater variety of skincare products on this page, and do they both include fragrances?

Shiseido offers a much greater variety of skincare products on this page compared to Sesderma, and yes, both brands include fragranced options across their selections.

What are the main skin types that Shiseido fits best according to its brand-focused routines?

According to its brand-focused routines, Shiseido fits sensitive skin, mature skin, and skin with dark spots best.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.