The Ordinary Multi-Peptide + HA Serum for dry skin
Multi-Peptides
Sodium Hyaluronate
Lactococcus Lysate Ferment
Acetyl Hexapeptide-8
Palmitoyl Tripeptide-1
Superior
- SuperiorDry Skin Fit
- HighEffectiveness
- ExcellentSafety
One of the best serums for dry skin.
This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Excellent suitability for your dry skin is provided by multiple peptides like Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1, which offer plumping and firming benefits, complemented by hydrating ingredients such as Sodium Hyaluronate Crosspolymer to address dryness and flakiness.
- The inclusion of Trehalose, Fructose, Glucose, and Maltose further enhances humectant action, supporting overall skin hydration for your dry skin type.
- The product is safe for your skin, containing soothing ingredients like Glycerin and Allantoin, and lacks any harsh or prohibited substances.
How to apply
- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
People Say
★4.4Overall rating based on 2.5k+ reviewsBased on a very large amount of data, users with dry, mature, or dehydrated skin frequently praise this serum for its ability to plump the skin and smooth texture, often noting a reduction in fine dehydration lines. While many appreciate it as an affordable "all-in-one" anti-aging solution, a minority of users report breakouts or a lack of visible results regarding deeper wrinkles.
Highlights
Deeply hydrates Mostly Mentioned
- “Surprisingly hydrated my skin very well in the dry mountain air.”
- “My skin feels more hydrated, smooth, and plump.”
- “It’s so hydrating for the skin.”
- “Left my skin feeling very moisturizing.”
Great value Often Mentioned
- “Good quality and good price.”
- “Buying the 60ml is better value... good value for money.”
- “Proof you don't need to spend a fortune for good science.”
- “Affordable and will last you months.”
Smooths texture Often Mentioned
- “It really improved the texture of my skin.”
- “Left my skin feeling so smooth.”
- “Noticeably smoother skin in 8 weeks.”
- “Improves skin smoothness and targets multiple signs of aging.”
Plumps and firms Sometimes Noted
- “Makes my skin feel so firm after use.”
- “Experience firmer, plumper, and more resilient skin.”
- “Improves the feel of skin elasticity.”
- “Skin feels tighter after.”
Reduces fine lines Sometimes Noted
- “I notice less of crows feet after.”
- “Fine lines around my eyes... look much less prominent.”
- “Targets dynamic lines and wrinkles.”
- “Helps significantly improve the appearance of crow's feet.”
Conflicts with actives Sometimes Noted
- “Avoid using direct acids, direct vitamin C... in the same routine.”
- “Can be complicated to use... peptides and Vitamin C don't play well.”
- “Hard to fit into my routine due to conflicts.”
- “Cannot use with my other acid toners.”
Unclear results Sometimes Noted
- “Didn't see exceptional results but good for a basic serum.”
- “Quite nice feeling but idk what it does honestly.”
- “Haven't noticed a huge difference in wrinkles yet.”
- “Good basic serum but don't expect miracles.”
Allergic reactions Rarely Noted
- “My eyes were swollen almost shut the morning after.”
- “Do not use if you have sensitive skin!!”
- “Caused a burning sensation immediately.”
- “Face turned red and itchy.”
Causes breakouts Rarely Noted
- “Some people say Buffet has made their skin break out.”
- “Worried about this product causing acne.”
- “Caused small bumps on my forehead.”
- “My skin broke out after a few days.”
Sources: lovi.care, theordinary.com, sephora.com, ulta.com, amazon.com, deciemchatroom.com, and more
Questions and answers
What makes The Ordinary Multi-Peptide + HA Serum one of the best fits for dry skin?
This serum is one of the best fits for your dry skin because multiple peptides help plump and firm while sodium hyaluronate addresses dryness and flakiness. Sugars like trehalose further boost hydration, and soothing ingredients like glycerin and allantoin provide a safe and calming experience.
Annals of Dermatology, 2019Skin Research and Technology, 2024
Which ingredients make this serum a good fit for dry skin?
This serum is an excellent fit for dry skin thanks to multiple peptides like Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1 that help plump and firm, alongside hydrating ingredients like Sodium Hyaluronate Crosspolymer and sugars such as Trehalose that tackle dryness and flakiness. Soothing ingredients like Glycerin and Allantoin also make it safe and gentle for your skin.
Annals of Dermatology, 2019Skin Research and Technology, 2024
What do Peptides do for dry skin?
Peptides help dry skin by boosting hydration, improving skin firmness, and smoothing out fine lines. They support the skin barrier so it stays soft and comfortable.
What does Hyaluronic Acid do for dry skin?
Hyaluronic acid draws moisture into dry skin, giving an immediate and lasting boost in hydration that helps smooth out fine lines and soften rough patches. It is very gentle and unlikely to cause irritation while improving overall skin smoothness and plumpness.
Dermatology and Therapy, 2021Journal of Drugs in Dermatology, 2011
Where does this serum go in a skincare routine for dry skin?
This treatment serum goes in the evening routine after cleansing and before moisturizing. Putting it in the evening keeps things simple and helps avoid extra safety concerns around sun exposure.
Can I use this serum with retinol, and in what order?
Yes, you can use this serum with retinol by applying the serum first to hydrate and soothe your dry skin, followed by your retinol. The gentle peptides and hydrating ingredients help keep your skin comfortable and are unlikely to cause irritation when layered.
American Journal of Clinical Dermatology, 2013Annals of Dermatology, 2019
How often should I use this serum?
You can use this treatment in your evening routine. It contains soothing ingredients like Glycerin and Allantoin, making it a low-risk addition to help manage dry skin and smooth fine lines.
Facial Plastic Surgery, 2014American Journal of Clinical Dermatology, 2013
Can this serum clog pores, cause breakouts or purging for dry skin?
This serum is unlikely to clog pores or cause breakouts for dry skin, as it contains soothing ingredients like glycerin and allantoin with a very low risk of breakouts. It helps keep skin calm and smooth while supporting hydration.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group.
American Journal of Clinical Dermatology, 2013Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days.
Annals of Dermatology, 2019Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects.
Journal of Cosmetic and Laser Therapy, 2013Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo.
Skin Research and Technology, 2024Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear.
Journal of Cosmetic Dermatology, 2017Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy.
European Journal of Neurology, 2013Dissolving microneedles loaded with 3-O-ethyl ascorbic acid and acetyl hexapeptide-8 achieved higher cumulative transdermal delivery than aqueous solutions and significantly reduced photoaging signs while restoring oxidative balance in a UV/D-galactose-induced mouse model.
International Journal of Biological Macromolecules, 2026A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.
Journal of Cosmetic Dermatology, 2015Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.
Journal of Cosmetic Dermatology, 2026Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components.
International Journal of Cosmetic Science, 2026
Ingredients
Water, Glycerin, Lactococcus Lysate Ferment, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium Pca, Pca, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, Ppg-26-Buteth-26, Peg-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Ethoxydiglycol, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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