The Ordinary Soothing & Barrier Support Serum for dry sensitive skin

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Questions and answers

What the research says

• Bakuchiol and ethyl (linoleate/oleate) synergistically inhibit eCB degradation to favor eCB mobilization and repress inflammatory mediators in keratinocytes.

  JID Innovations, 2023

• Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

  Indian Journal of Pharmaceutical Sciences, 2016

• Panthenyl triacetate (PTA) demonstrated skin de-acetylation into panthenol, stimulated energetic and synthesis metabolic pathways, and achieved a statistically significant improvement in wound healing after 72 hours compared to saline treatment in human volunteers, outperforming panthenol in long-lasting wound healing action.

  Journal of Cosmetic Science, 2012

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• The novel high-payload nanosuspension system of Centella asiatica extract increased skin accumulation of asiatic acid, madecassic acid, and asiaticoside by 5-, 4-, and 4.5-fold respectively compared to a marketed cream in porcine skin, with no local skin irritation in normal rats.

  International Journal of Nanomedicine, 2021

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.

  Journal of Alternative and Complementary Medicine, 2020

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline.

  Experimental Dermatology, 2008

Ingredients

Water, Propanediol, Isodecyl Neopentanoate, Pentylene Glycol, Niacinamide, Hexyldecanol, Cetearyl Alcohol, Xylitylglucoside, Ceteth-20 Phosphate, Anhydroxylitol, Ethyl Linoleate, Asiaticoside, Asiatic Acid, Madecassic Acid, Naringenin, Cyanocobalamin, Panthenyl Triacetate, 4-T-Butylcyclohexanol, Hydroxyphenyl Propamidobenzoic Acid, Cetylhydroxyproline Palmitamide, Bisabolol, Brassica Campestris Sterols, Sphingolipids, Epigallocatechin Gallatyl Glucoside, Gallyl Glucoside, Propyl Gallate, Xylitol, Zingiber Officinale Root Extract, Stearic Acid, Dicetyl Phosphate, Isoceteth-20, Xanthan Gum, Trisodium Ethylenediamine Disuccinate, Tocopherol, Dehydroacetic Acid, P-Anisic Acid, Phytic Acid, Sodium Phytate, Sodium Citrate, Sodium Hydroxide, Benzyl Alcohol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.