Shiseido Ultimune Power Infusing Concentrate for acne-prone skin
Imugenerationred Technology
Rosa Damascena Flower Water
Ginkgo Biloba Leaf Extract
Tocopheryl Acetate
Ganoderma Lucidum Stem Extract Mushroom Stem ExtractLow
- AverageCombination Skin Fit
- AverageEffectiveness
- HighSafety
A weak match for acne-prone skin; the serums alongside fit it better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate skin treatment for your combination skin, as Glycerin and Trehalose provide essential hydration and soothing benefits supportive for acne and blemishes.
- While the formula is generally safe and free from harsh irritants, it lacks specific ingredients for optimal oil control, which is a key concern for combination skin.
- The safety profile is excellent, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
People Say
★4.6Overall rating based on 2.9k+ reviewsBased on a very large amount of data, users consistently describe this serum as a lightweight, fast-absorbing "pre-serum" that significantly boosts hydration and radiance, leaving skin feeling softer and smoother. Many report a visible "glow" and improved resilience against aging signs. Some users with sensitive skin find the fragrance and alcohol content irritating, and others feel the high price tag isn't justified by the results.
Highlights
Fast absorption Mostly Mentioned
- “Lightweight, silky, non-sticky, sinks in instantly.”
Hydration boost Often Mentioned
- “Leaves skin soft, dewy, and moisturized.”
Increases radiance Often Mentioned
- “Skin looks brighter, more radiant, and "glowy."”
High price Often Mentioned
- “Expensive, pricey, high cost for the amount.”
Pleasant scent Sometimes Noted
- “Pleasant floral fragrance, relaxing, luxurious smell.”
Smoother skin Sometimes Noted
- “Improves texture, plumps skin, reduces visible pores.”
Fragrance/alcohol Sometimes Noted
- “Strong scent, alcohol smell, potential irritation for sensitive skin.”
Lack of results Rarely Noted
- “No noticeable difference, not moisturizing enough on its own.”
Packaging issues Rarely Noted
- “Heavy bottle but plastic pump, cannot see remaining product, straw too short to get last drops.”
Skin reactions Rarely Noted
- “Caused breakouts, redness, or exacerbated oiliness for some.”
Sources: lovi.care, sephora.hk, macys.com, nordstrom.com, ulta.com, walmart.com, and more
Questions and answers
Why is Shiseido Ultimune Power Infusing Concentrate a weak match for acne-prone skin?
This treatment is a weak match because it lacks specific ingredients for optimal oil control, which is a key concern for this skin type. A product of this type needs effective ingredients like niacinamide, zinc PCA, and propolis to manage breakouts and oiliness.
Which ingredients make this serum a poor fit for acne-prone skin?
This serum is a weak match for acne-prone skin because it lacks targeted oil-control ingredients, even though it provides soothing hydration through glycerin and trehalose. Treatment products of this type need effective ingredients like niacinamide, zinc PCA, and propolis to balance oiliness and care for breakouts without causing irritation.
What does Imugenerationred Technology do for acne-prone skin?
Imugenerationred Technology is unlikely to directly treat acne-prone skin, as its focus is on boosting overall skin defense rather than clearing breakouts. To properly care for acne-prone skin, a product needs soothing ingredients and oils that help calm redness and clear pores.
What does Rose Flower Water do for acne-prone skin?
Rose Flower Water helps calm red or irritated skin and may fight breakout-causing bacteria. It is generally well tolerated and unlikely to cause irritation when used in everyday skincare routines.
Biological & Pharmaceutical Bulletin, 2017Journal of Cosmetic Dermatology, 2024
Where does this serum go in a skincare routine for acne-prone skin?
This serum goes in the evening routine for acne-prone skin, after cleansing and before moisturizing. Because this product is a weak match for acne-prone skin, a treatment for this skin type needs specific ingredients for oil control to keep skin balanced and calm.
Can I use this serum with retinol, and in what order?
You can use this treatment alongside retinol by applying the treatment first and following with your retinol once it absorbs. This product is a weak match for acne-prone skin because it lacks oil-controlling ingredients, so a product of this type needs balancing ingredients like glycerin and trehalose to keep skin calm without excess oil.
How often should I use this serum?
This serum is a weak match for your acne-prone skin because it lacks specific ingredients for optimal oil control. To properly care for acne-prone skin, a product of this type needs targeted oil-controlling ingredients to keep pores clear and balance oil production.
Can this serum clog pores, cause breakouts or purging for acne-prone skin?
This treatment is a weak match for acne-prone skin because it lacks oil-control ingredients, though it is unlikely to irritate. Acne-prone skin needs products with targeted oil-controlling ingredients to keep pores clear.
Is this serum fragrance-free and alcohol-free?
It contains fragrance (parfum, linalool, geraniol, and citronellol) and drying alcohol (alcohol denat).
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo.
Skin Research and Technology, 2024Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.
Contemporary Clinical Trials Communications, 2021Treatment with a rose extract activated newly identified skin olfactory receptors and prevented epinephrine-induced skin stress responses in epidermal keratinocytes and human skin explants, while clinically decreasing the appearance of under-eye dark circles in stressed women.
Molecules, 2020Rose petal extract improves stratum corneum moisture levels in humans by upregulating HAS2 expression via the GLK-MAP2K-MAPK signaling pathway.
BioFactors, 2023Rosa gallica petal extract (RPE) exerts skin whitening by attenuating tyrosinase activity and melanin accumulation and exhibits anti-wrinkle activity by suppressing MMP-1 levels in human cells.
Journal of Medicinal Food, 2020Topical application of a 2% cream containing combined fruit extracts for 56 days significantly reduced wrinkle depth by 11.5%, length by 10.07%, and area by 29.55% in 21 female subjects compared to a placebo.
Clinical, Cosmetic and Investigational Dermatology, 2015A dermocosmetic containing bakuchiol, Ginkgo biloba extract, and mannitol improves inflammatory lesions, Investigator Global Assessment, and seborrhea intensity when added to adapalene 0.1% gel in patients with acne vulgaris.
Clinical, Cosmetic and Investigational Dermatology, 2015Topical application of Ginkgo biloba cream for two weeks reduced wrinkles and improved skin shape, texture, and tautness in human volunteers compared to baseline.
Drug Development and Industrial Pharmacy, 2023Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.
Journal of Cosmetic Dermatology, 2025Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.
Journal of Cosmetic Dermatology, 2024A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use.
Journal of Cosmetic Dermatology, 2022Topical application of soap enriched with Ganoderma lucidum and goat's milk for 3 days resulted in almost complete regression of annular cutaneous sarcoidosis lesions in a 44-year-old male patient.
Dermatology and Therapy, 2016Ganoderma lucidum polysaccharides at concentrations of 10, 20, and 40 ΓΖg/mL significantly increased fibroblast viability, migration, and CICP and TGF-Β1 expression compared to the control group, and external use in mice significantly increased wound healing rates and reduced healing time.
Chinese Journal of Integrative Medicine, 2019Ethanolic extracts of Ganoderma lucidum rich in triterpenoids and phenolic acids exhibit antioxidant, anti-inflammatory, antityrosinase, antimicrobial, and cytotoxic effects, and can be successfully incorporated into topical cosmeceutical formulations while preserving their bioactivities.
Food and Chemical Toxicology, 2017
Why other serums fit acne-prone skin better
A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.
Journal of Cosmetic Dermatology, 2024A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.
Clinical Pharmacology, 2018Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris.
The Journal of Clinical and Aesthetic Dermatology, 2020
Ingredients
Water, Alcohol Denat, Glycerin, Butylene Glycol, Dimethicone, Diglycerin, Peg Ppg-17 4 Dimethyl Ether, Phenoxyethanol, Triethylhexanoin, Isodecyl Neopentanoate, Trehalose, Ammonium Acryloyldimethyltaurate Beheneth-25 Methacrylate Crosspolymer, Peg-14m, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Peg Ppg-14 7 Dimethyl Ether, Tocopheryl Acetate, Rosa Damascena Flower Water, Parfum, Disodium Edta, Potassium Hydroxide, Silica, Isoceteth-10, Linalool, Lauryl Betaine, Ginkgo Biloba Leaf Extract, Geraniol, Citronellol, Origanum Majorana Leaf Extract, Nelumbo Nucifera Germ Extract, Sodium Carboxymethyl Beta-Glucan, Bht, Thymus Serpyllum Extract, Perilla Ocymoides Leaf Extract, Sodium Bicarbonate, Iris Florentina Root Extract, Sodium Benzoate, Ganoderma Lucidum Stem Extract Mushroom Stem Extract
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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