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Shiseido vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Shiseido and Sesderma are distinguished skincare brands originating from Japan and Spain, respectively. The Japanese house is cherished for its nourishing moisturizers, gentle cleansers, protective sunscreens, potent serums, and versatile glycerin formulations, while the Spanish house is beloved for its advanced serums and meticulously engineered formulas. Shiseido suits mature and sensitive skin best, offering deep moisture and gentle care through products like the Treatment Softener, the Benefiance Wrinkle Smoothing Day Cream, and the Essential Energy Hydrating Cream, whereas Sesderma targets sensitive, hyperpigmented, and aging complexions with standout offerings such as the Azelac RU Serum. Ultimately, they differ in their heritage and specific active approaches, with the former relying on rigorously studied glycerin for stratum corneum hydration and the latter utilizing botanical extracts and active compounds to refine texture.

Shiseido is a Japanese skincare brand founded in 1872 and owned by Shiseido Company, Limited.

corp.shiseido.comen.wikipedia.orgmarketscreener.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Shiseido and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Shiseido vs Sesderma products

Questions and answers

Shiseido or Sesderma: which is better?

Shiseido is often better for a wide variety of skincare needs, as the products on this page provide options that Lovi rates as Superior or High for mature, sensitive, and dry skin. Hyaluronic acid helps retain moisture in the skin.

Dermatologic Therapy, 2022

What is the difference between Shiseido and Sesderma?

Shiseido features a broad range of twenty skincare products on this page that are formulated with ingredients like glycerin and hyaluronic acid, whereas Sesderma offers just a single serum. Topical hyaluronic acid helps improve skin quality and signs of aging.

Dermatologic Therapy, 2022

Which is more affordable, Shiseido or Sesderma?

Reviewers note that Shiseido products on this page have a high price point. The page facts do not mention pricing information for Sesderma.

Which causes fewer breakouts, Shiseido or Sesderma?

The products on this page for both Shiseido and Sesderma include formulas that may help with acne-prone skin, though some individual items like Shiseido's Ultimate Sun Protector Lotion are rated with a low fit level for acne-prone skin.

How does the founding year and country of origin compare between Shiseido and Sesderma?

Shiseido was founded in Japan in 1872, whereas Sesderma was founded in Spain in 1989.

What are the main fragrance characteristics of Shiseido products versus Sesderma products based on the page?

On the products on this page, Shiseido includes fragrance in 15 of its 20 products, while Sesderma features fragrance in all 1 of its listed products.

Which brand offers a wider variety of product types, such as sunscreens, toners, and cleansers, on this page?

Shiseido offers a much wider variety of product types on this page, featuring cleansers, toners, sunscreens, serums, and moisturizers, whereas Sesderma only features a single serum.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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