🇸🇬Singapore

The Ordinary Multi-Peptide + HA Serum for combination skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

The Ordinary Multi-Peptide + HA Serum

High

  • SuperiorCombination Skin Fit
  • HighEffectiveness
  • ExcellentSafety

One of the best serums for combination skin.

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers excellent plumping and firming for your combination skin due to multiple peptides like Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1, which stimulate collagen and improve texture, alongside hydrating ingredients such as Sodium Hyaluronate Crosspolymer.
  • The presence of humectants like Glycerin and Urea provides optimal skin barrier support, though it lacks specific ingredients for oil control to fully address your oily shine concern.
  • The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing agents like Allantoin.

How to apply

  • Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
  • Apply the serum after cleansing and toner, and right before your moisturizer.
  • Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
  • Apply the serum on clean and dry skin since your skin is not sensitive.
  • Always do a patch test before using the serum for the first time, and avoid the eye area .

People Say

★4.4Overall rating based on 2.5k+ reviews

Based on a very large amount of data, users with dry, mature, or dehydrated skin frequently praise this serum for its ability to plump the skin and smooth texture, often noting a reduction in fine dehydration lines. While many appreciate it as an affordable "all-in-one" anti-aging solution, a minority of users report breakouts or a lack of visible results regarding deeper wrinkles.

Highlights

  • Deeply hydrates Mostly Mentioned
    • “Surprisingly hydrated my skin very well in the dry mountain air.”
    • “My skin feels more hydrated, smooth, and plump.”
    • “It’s so hydrating for the skin.”
    • “Left my skin feeling very moisturizing.”
  • Great value Often Mentioned
    • “Good quality and good price.”
    • “Buying the 60ml is better value... good value for money.”
    • “Proof you don't need to spend a fortune for good science.”
    • “Affordable and will last you months.”
  • Smooths texture Often Mentioned
    • “It really improved the texture of my skin.”
    • “Left my skin feeling so smooth.”
    • “Noticeably smoother skin in 8 weeks.”
    • “Improves skin smoothness and targets multiple signs of aging.”
  • Plumps and firms Sometimes Noted
    • “Makes my skin feel so firm after use.”
    • “Experience firmer, plumper, and more resilient skin.”
    • “Improves the feel of skin elasticity.”
    • “Skin feels tighter after.”
  • Reduces fine lines Sometimes Noted
    • “I notice less of crows feet after.”
    • “Fine lines around my eyes... look much less prominent.”
    • “Targets dynamic lines and wrinkles.”
    • “Helps significantly improve the appearance of crow's feet.”
  • Conflicts with actives Sometimes Noted
    • “Avoid using direct acids, direct vitamin C... in the same routine.”
    • “Can be complicated to use... peptides and Vitamin C don't play well.”
    • “Hard to fit into my routine due to conflicts.”
    • “Cannot use with my other acid toners.”
  • Unclear results Sometimes Noted
    • “Didn't see exceptional results but good for a basic serum.”
    • “Quite nice feeling but idk what it does honestly.”
    • “Haven't noticed a huge difference in wrinkles yet.”
    • “Good basic serum but don't expect miracles.”
  • Allergic reactions Rarely Noted
    • “My eyes were swollen almost shut the morning after.”
    • “Do not use if you have sensitive skin!!”
    • “Caused a burning sensation immediately.”
    • “Face turned red and itchy.”
  • Causes breakouts Rarely Noted
    • “Some people say Buffet has made their skin break out.”
    • “Worried about this product causing acne.”
    • “Caused small bumps on my forehead.”
    • “My skin broke out after a few days.”

Sources: lovi.care, theordinary.com, sephora.com, ulta.com, amazon.com, deciemchatroom.com, and more

Questions and answers

What makes The Ordinary Multi-Peptide + HA Serum a great fit for combination skin?

This serum is a great fit because it offers excellent firming and keeps your skin smooth with multiple peptides like Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1, while sodium hyaluronate adds deep hydration without feeling heavy. It also supports your skin barrier nicely with glycerin and urea, and is very unlikely to cause irritation.

American Journal of Clinical Dermatology, 2013Journal of Cosmetic and Laser Therapy, 2013

Which ingredients make this serum a good fit for combination skin?

This serum is a great fit for your combination skin because it features multiple peptides like Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1 to firm and smooth, alongside Sodium Hyaluronate Crosspolymer and Glycerin to provide deep hydration.

American Journal of Clinical Dermatology, 2013Journal of Cosmetic and Laser Therapy, 2013

What do Peptides do for combination skin?

Peptides help combination skin by supporting firmness, smoothing out wrinkles, and improving hydration without feeling heavy. They work by encouraging collagen production, which may help keep the skin looking smooth and bouncy.

International Journal of Molecular Sciences, 2025International Journal of Molecular Medicine, 2017

What does Hyaluronic Acid do for combination skin?

Hyaluronic acid is a great fit for combination skin because it quenches dry areas with a boost of hydration while keeping oily zones balanced. Regular use helps smooth out fine lines and makes your skin feel soft and plump without causing irritation.

Dermatology and Therapy, 2021Journal of Drugs in Dermatology, 2011

Where does it go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing and before moisturizing, as putting it in the evening offers extra safety around sun exposure. It is unlikely to irritate your skin because of its soothing ingredients.

Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying the serum first to hydrate and soothe your skin before adding your retinol step. This product is very safe and unlikely to cause irritation.

How often should I use it?

Apply this treatment in your evening routine, using it once a day or a few times a week as your skin feels comfortable. It is unlikely to cause irritation and helps keep your skin feeling smooth and firm.

American Journal of Clinical Dermatology, 2013Journal of Cosmetic and Laser Therapy, 2013

Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to clog pores or cause breakouts on combination skin because it has an excellent safety profile without harsh ingredients. Reviewers rarely mention breakouts, and the formula includes soothing agents like Allantoin to help keep skin calm.

Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group.

    American Journal of Clinical Dermatology, 2013

  • Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects.

    Journal of Cosmetic and Laser Therapy, 2013

  • Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days.

    Annals of Dermatology, 2019

  • Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.

    Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016

  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011

  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022

  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019

  • Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear.

    Journal of Cosmetic Dermatology, 2017

  • Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy.

    European Journal of Neurology, 2013

  • Dissolving microneedles loaded with 3-O-ethyl ascorbic acid and acetyl hexapeptide-8 achieved higher cumulative transdermal delivery than aqueous solutions and significantly reduced photoaging signs while restoring oxidative balance in a UV/D-galactose-induced mouse model.

    International Journal of Biological Macromolecules, 2026

  • A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.

    Journal of Cosmetic Dermatology, 2015

  • Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.

    Journal of Cosmetic Dermatology, 2026

  • Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components.

    International Journal of Cosmetic Science, 2026

Ingredients

Water, Glycerin, Lactococcus Lysate Ferment, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium Pca, Pca, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, Ppg-26-Buteth-26, Peg-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Ethoxydiglycol, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

Scan your face, then any product.

QR code: get the Lovi app
Download on theApp Store Get it onGoogle Play

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.

QR code: get the Lovi app
Download on theApp Store Get it onGoogle Play