Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence
Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022Topical use of dexpanthenol in skin disorders
Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review
Aloe barbadensis leaf water · Iranian Journal of Medical Sciences, 2019Improvement of naturally aged skin with vitamin A (retinol)
Retinol · Archives of Dermatology, 2007Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo
Sodium ascorbyl phosphate ascorbic acid, Ascorbyl palmitate ascorbic acid · Experimental Dermatology, 2003Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial
Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Retinol · International Journal of Cosmetic Science, 2017Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin
Palmitoyl pentapeptide-4 · International Journal of Cosmetic Science, 2005Effects of menthol and cold on histamine-induced itch and skin reactions in man
Peppermint leaf extract · Neuroscience Letters, 1995Anti-microbial and -inflammatory activity and efficacy of phytosphingosine: an in vitro and in vivo study addressing acne vulgaris
Phytosphingosine · International Journal of Cosmetic Science, 2007Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing
Bakuchiol · The British Journal of Dermatology, 2019Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Sodium ascorbyl phosphate ascorbic acid · Journal of Periodontology, 2009Antiaging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skin
Panax ginseng root extract · Journal of Ginseng Research, 2017Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women
Oxidized glutathione · Clinical, Cosmetic and Investigational Dermatology, 2014Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling
Panax ginseng root extract · Journal of Ethnopharmacology, 2007Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract
Asiaticoside, Madecassic acid · Indian Journal of Pharmaceutical Sciences, 2016Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter
Titanium dioxide · International Journal of Cosmetic Science, 2000The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction
Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
Squalane · Scientific Reports, 2020Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations
Aloe barbadensis leaf juice powder · Clinical Pharmacology, 2018Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin
Ceramides · Scientific Reports, 2022Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study
Ascorbic acid · Clinical Oral Investigations, 2021Glycolipid biosurfactants, mannosylerythritol lipids, show antioxidant and protective effects against H(2)O(2)-induced oxidative stress in cultured human skin fibroblasts
Glycolipids · Journal of Oleo Science, 2012Effects of Locally Applied Glycerol and Xylitol on the Hydration, Barrier Function and Morphological Parameters of the Skin
Xylitol, Xylitylglucoside · Acta Dermato-venereologica, 2017Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin
Ceramide np · International Journal of Dermatology, 2008Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation
Ascorbic acid · Journal of Cosmetic Dermatology, 2020Characterisation of cytotoxicity and immunomodulatory effects of glycolipid biosurfactants on human keratinocytes
Glycolipids · Applied Microbiology and Biotechnology, 2023Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris
Azelaic acid · Pharmaceutics, 2021Design, characterization, and clinical evaluation of argan oil nanostructured lipid carriers to improve skin hydration
Argania spinosa kernel oil · International Journal of Nanomedicine, 2014Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls
Camellia sinensis leaf extract · Experimental Dermatology, 2009Anti-inflammatory activities of colloidal oatmeal (Avena sativa) contribute to the effectiveness of oats in treatment of itch associated with dry, irritated skin
Avena sativa kernel extract oat kernel extract · Journal of Drugs in Dermatology, 2015The moisturizing effects of glycolipid biosurfactants, mannosylerythritol lipids, on human skin
Glycolipids · Journal of Oleo Science, 2012The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study
Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy
Niacinamide, Gentlebright complex · Journal of Cosmetic Dermatology, 2021The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial
Madecassic acid · Journal of Alternative and Complementary Medicine, 2020Niacinamide mitigates SASP-related inflammation induced by environmental stressors in human epidermal keratinocytes and skin
Gentlebright complex · International Journal of Cosmetic Science, 2020The human stratum corneum layer: an effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide
Titanium dioxide · Skin Pharmacology and Applied Skin Physiology, 2001Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial
Acetyl glucosamine · The British Journal of Dermatology, 2010Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
Acetyl glucosamine · Journal of Cosmetic Dermatology, 2007Anti-Aging Effects of Leontopodium alpinum (Edelweiss) Callus Culture Extract Through Transcriptome Profiling
Leontopodium alpinum extract · Genes, 2020The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study
Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013Two superior antioxidants: Ferulic acid and ascorbic acid in reducing signs of photoaging-A split-face comparative study
Sodium ascorbyl phosphate ascorbic acid · Dermatologic Therapy, 2022A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora
Panthenol, Panthenol vitamin b5 · The Journal of Dermatological Treatment, 2017Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study
Glycolic acid · Journal of Cosmetic Dermatology, 2019A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population
Salicylic acid · BioMed Research International, 2020Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging
Niacinamide · Scientific Reports, 2024Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation
Tocopheryl acetate vitamin e, Tocopheryl acetate vitamin e acetate · Urologia Internationalis, 2019Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin
Ascorbyl palmitate ascorbic acid · Antioxidants, 2024Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris
Mandelic acid · Journal of Cosmetic Dermatology, 2020Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide
Moisturizing factors · The Journal of Clinical and Aesthetic Dermatology, 2012Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration
Adenosine · International Journal of Cosmetic Science, 2018Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant
Caffeine · Frontiers in Physiology, 2019Structural characterization and in vivo evaluation of retinyl palmitate in non-ionic lamellar liquid crystalline system
Retinyl palmitate · Colloids and Surfaces. B, Biointerfaces, 2011A Dunaliella salina Extract Counteracts Skin Aging under Intense Solar Irradiation Thanks to Its Antiglycation and Anti-Inflammatory Properties
Dunaliella salina extract · Marine Drugs, 2022The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study
Pha polyhydroxy acid · Clinical, Cosmetic and Investigational Dermatology, 2019High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin
Witch hazel leaf water · Phytochemistry, 2001Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial
Panthenol vitamin b5, Panthenol, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study
Vitamin c derivative · Photochemistry and Photobiology, 2021Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin
Acetyl hexapeptide-8 · Annals of Dermatology, 2019Double-blind, randomized, placebo-controlled study of a lotion containing triethyl citrate and ethyl linoleate in the treatment of acne vulgaris
Ethyl linoleate · The British Journal of Dermatology, 2007Characterization of Acne-Prone Skin with Reflectance Confocal Microscopy and Optical Coherence Tomography and Modifications Induced by Topical Treatment and Probiotic Supplementation
Hydroxypinacolone retinoate · Journal of Clinical Medicine, 2023Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula
Saccharomyces ferment filtrate · Journal of Clinical Medicine, 2021In vivo anti-ageing activity of cream containing niosomes loaded with purple glutinous rice (Oryza sativa Linn.) extract
Rice extract lees extract · International Journal of Cosmetic Science, 2020A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Pha polyhydroxy acid · The Australasian Journal of Dermatology, 1992Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study
Salicylic acid · Journal of Cosmetic Dermatology, 2024High-Payload Nanosuspension of Centella asiatica Extract for Improved Skin Delivery with No Irritation
Asiaticoside · International Journal of Nanomedicine, 2021Comparative Study of 35% Glycolic Acid, 20% Salicylic-10% Mandelic Acid, and Phytic Acid Combination Peels in the Treatment of Active Acne and Postacne Pigmentation
Phytic acid · Journal of Cutaneous and Aesthetic Surgery, 2019Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach
Zinc oxide · Journal of Controlled Release, 2025Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects
Vitamin e · Journal of Cosmetic Dermatology, 2020Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study
Jojoba seed oil · Forschende Komplementarmedizin, 2012Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications
Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid
Ceramide np · Skin Pharmacology and Physiology, 2022Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment
Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris
Azelaic acid · Dermatology and Therapy, 2024A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide
Salicylic acid · Journal of Drugs in Dermatology, 2023Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study
Moisturizing factors · Molecules, 2021Encapsulation of alpha arbutin, a depigmenting agent, in nanosized ethosomes: Invitro and invivo human studies
Alpha-arbutin, Alpha arbutin · Heliyon, 2023Colloidal Oatmeal <em>(Avena Sativa)</em> Improves Skin Barrier Through Multi-Therapy Activity
Avena sativa kernel extract oat kernel extract · Journal of Drugs in Dermatology, 2016Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs
Vitamin e · Journal of Cosmetic Dermatology, 2022Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial
Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function
Propanediol · International Journal of Cosmetic Science, 2024Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial
Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020Evaluating the Safety and Efficacy of a Topical Formulation Containing Epidermal Growth Factor, Tranexamic Acid, Vitamin C, Arbutin, Niacinamide and Other Ingredients as Hydroquinone 4% Alternatives to Improve Hyperpigmentation: A Prospective, Randomized, Controlled Split Face Study
Alpha arbutin · Journal of Cosmetic Science, 2020Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model
Jojoba seed oil · Frontiers in Pharmacology, 2024Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)
Sodium laureth sulfate · Food and Chemical Toxicology, 2001The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study
Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris
Citric acid · Journal of Cosmetic Dermatology, 2021The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study
Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017Whitening effect of alpha-bisabolol in Asian women subjects
Bisabolol · International Journal of Cosmetic Science, 2010Lycopene and Melatonin: Antioxidant Compounds in Cosmetic Formulations
Solanum lycopersicum fruit extract tomato fruit extract · Skin Pharmacology and Physiology, 2020In Vitro and Clinical Safety Assessment of the Multiple W/O/W Emulsion Based on the Active Ingredients from Rosmarinus officinalis L., Avena sativa L. and Linum usitatissimum L
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Granactive retinoid · Giornale Italiano Di Dermatologia E Venereologia, 2020Administration of skin care regimens containing β-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study
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Phytoceramides · Journal of Cosmetic Dermatology, 2024Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging
Pentylene glycol · International Journal of Molecular Sciences, 2018Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers
Sodium ascorbyl phosphate · Drug Research, 2017Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration
Betaine · Molecules, 2024Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine
Acetyl glucosamine · Advanced Pharmaceutical Bulletin, 2016The impacts of sodium lauroyl sarcosinate in facial cleanser on facial skin microbiome and lipidome
Sodium lauroyl sarcosinate · Journal of Cosmetic Dermatology, 2024Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement
Adenosine · Journal of Cosmetic Dermatology, 2019Permeation, metabolism and site of action concentration of nicotinic acid derivatives in human skin. Correlation with topical pharmacological effect
Hexyl nicotinate · European Journal of Pharmaceutical Sciences, 2003Randomized prospective study of low-dose isotretinoin alone and combination with salicylic acid and mandelic peel against acne tarda
Mandelic acid · Journal of Cosmetic Dermatology, 2022Depth-dependent hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a functional 10% urea plus NMF moisturizer by near-infrared confocal spectroscopic imaging (KOSIM IR) and capacitance method complemented by volunteer perception
Moisturizing factors · Skin Research and Technology, 2022Panthenyl triacetate transformation, stimulation of metabolic pathways, and wound-healing properties in the human skin
Panthenyl triacetate · Journal of Cosmetic Science, 2012Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
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Dimethicone · Ostomy/wound Management, 2005Evaluation of wound healing potential of new composite liposomal films containing coenzyme Q10 and d-panthenyl triacetate as combinational treatment
Panthenyl triacetate · Pharmaceutical Development and Technology, 2021The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively
Betaine · Skin Research and Technology, 2003Topical lycopene emulgel significantly improves biophysical parameters of human skin
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Phytic acid · Journal of Cosmetic Dermatology, 2011Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores
Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007Influence of vitamin E acetate on stratum corneum hydration
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Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles
Phenylethyl resorcinol · Journal of Cosmetic Dermatology, 2021Comparative physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of 5% sodium ascorbyl phosphate and or ascorbic acid on human volunteers
Sodium ascorbyl phosphate · Journal of Cosmetic Dermatology, 2021Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials
Ascorbyl palmitate ascorbic acid · Frontiers in Pharmacology, 2025Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence
Zinc oxide · Biomedicines, 2025Modulation of lipid fluidity likely contributes to the fructose/xylitol-induced acceleration of epidermal permeability barrier recovery
Xylitylglucoside · Archives of Dermatological Research, 2019Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study
Panthenol, Panthenol vitamin b5 · Journal of Cosmetic Dermatology, 2025Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study
Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026Hexyl-nicotinate-induced vasodilation in normal human skin
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Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays
Xylitylglucoside · Molecules, 2021Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer
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Sodium ascorbyl phosphate · Experimental Dermatology, 2012Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin
Vitamin e · Journal of Cosmetic Dermatology, 2024The effect of a vitamin A palmitate and antioxidant-containing oil-based moisturizer on photodamaged skin of several body sites
Retinyl palmitate · Journal of Cosmetic Dermatology, 2013Modulating effects of oatmeal extracts in the sodium lauryl sulfate skin irritancy model
Avena sativa kernel extract oat kernel extract · Skin Pharmacology and Applied Skin Physiology, 2002Tasmannia lanceolata leaf extract alleviates stretch mark appearance in a randomized, placebo-controlled clinical trial in women and stimulates extracellular matrix synthesis in ex vivo human skin explants
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Caprylic capric triglyceride · Life, 2023A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females
Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris
Citric acid · Journal of Drugs in Dermatology, 2013Preliminary safety and in vivo efficacy of Acmella oleracea extract-loaded glycolipid emulsion serum-Effects on ocular irritation, dermal absorption, and facial skin biophysical and microrelief properties
Glycolipids · International Journal of Cosmetic Science, 2025Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy
Tocopheryl acetate vitamin e, Tocopheryl acetate vitamin e acetate, Tocopheryl acetate · Scientific Reports, 2025Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence
Adenosine · International Journal of Molecular Sciences, 2026Evaulation of irritation potential of surfactant mixtures
Sodium laureth sulfate · International Journal of Cosmetic Science, 1999A bioactive complex to protect proteins from UV-induced oxidation in human epidermis
Panthenyl triacetate · International Journal of Cosmetic Science, 2010Bakuchiol and Ethyl (Linoleate/Oleate) Synergistically Modulate Endocannabinoid Tone in Keratinocytes and Repress Inflammatory Pathway mRNAs
Ethyl linoleate · JID Innovations, 2023Efficacy of Topical Hydroxypinacolone Retinoate-Peptide Product Versus Fractional CO2 Laser in Facial Aging
Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2025Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months-An 11-Year Longitudinal Skin Aging Rejuvenation Study
Saccharomyces ferment filtrate · Journal of Clinical Medicine, 2023Preliminary evaluation of a comprehensive skincare regimen for enhancing skin health following advanced optimal pulse technology (AOPT) treatment
Ergothioneine · International Journal of Cosmetic Science, 2025Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
Ascorbyl glucoside · International Journal of Molecular Sciences, 2024A cleanser formulated with Tris (hydroxymethyl) aminomethane and l-arginine significantly improves facial acne in male Thai subjects
Arginine · Journal of Cosmetic Dermatology, 2020Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial
Tocopheryl acetate vitamin e, Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021Facial disbiosis and UV filters
Octocrylene · Archives of Dermatological Research, 2024A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
Pha polyhydroxy acid · Cutis, 2004A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties
Bakuchiol · Skin Research and Technology, 2026Natural Moisturizing Factor-Enriched Formulations Compared to a Ceramide-Based Cream
Moisturizing factors · Journal of Drugs in Dermatology, 2024Salicylic acid peel incorporating triethyl citrate and ethyl linoleate in the treatment of moderate acne: a new therapeutic approach
Ethyl linoleate · Dermatologic Surgery, 2013The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color
Saccharomyces ferment filtrate · Skinmed, 2021Ergothioneine, collagen peptides, and sodium hyaluronate ameliorate facial skin aging via modulating oxidative stress, inflammation, and extracellular matrix homeostasis
Ergothioneine · Frontiers in Nutrition, 2026Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking
Palmitoyl tetrapeptide-7 · International Journal of Cosmetic Science, 2026Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial
Argania spinosa kernel oil · Lasers in Medical Science, 2025Synergistic combination: Developing a natural carrier-free assembled gel through hydrogen bond reconstruction strategy for efficient skin photo-damage restoration
Sodium pca · Biomaterials Advances, 2026Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial
Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population
Bakuchiol · Health Science Reports, 2025Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study
Sodium laureth sulfate · International Journal of Pharmaceutics, 2026