The Ordinary Retinol 0.5% in Squalane for oily acne-prone skin
Retinol
Squalane
Caprylic Capric Triglyceride
Jojoba Seed Oil
Solanum Lycopersicum Fruit Extract Tomato Fruit Extract
Average
- HighOily Skin Fit
- AverageEffectiveness
- HighSafety
Works for oily acne-prone skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers excellent visible anti-aging effects for your oily skin due to retinol's desquamation and seboregulation properties, complemented by squalane for emollient action without heaviness.
- While providing general hydration and anti-aging benefits, the formula lacks targeted ingredients to address your specific concerns of acne, blemishes, and breakouts.
- The product is safe for your oily skin, with no risks of irritation due to the absence of harsh ingredients.
How to apply
- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
People Say
★4.3Overall rating based on 1.1k+ reviewsBased on a very large amount of data, users generally praise this serum as an affordable and effective entry-level retinol that improves skin texture and reduces fine lines, though the oily squalane base is a polarizing feature. While many with dry or mature skin appreciate the added hydration, those with oily or acne-prone skin frequently report that it feels heavy, greasy, and can cause congestion or purging.
Highlights
Improves skin texture Mostly Mentioned
- “smooths roughness”
- “softens skin”
- “glowing complexion”
Unbeatable price Mostly Mentioned
- “great value”
- “affordable”
- “budget-friendly”
Hydrating formula Often Mentioned
- “non-drying”
- “moisturizing oil”
- “prevents flaking”
Reduces aging signs Often Mentioned
- “fades fine lines”
- “plumps wrinkles”
- “firmer skin”
Greasy residue Often Mentioned
- “sits on skin”
- “doesn't absorb”
- “oily film”
Gentle effectiveness Sometimes Noted
- “low irritation”
- “good for beginners”
- “minimal redness”
Causes breakouts Sometimes Noted
- “purging phase”
- “cystic acne”
- “clogged pores”
Short shelf life Sometimes Noted
- “expires quickly”
- “requires refrigeration”
- “3-month limit”
Messy packaging Rarely Noted
- “leaky dropper”
- “stains pillowcases”
- “greasy bottle”
Unpleasant scent Rarely Noted
- “cooking oil smell”
- “earthy odor”
- “stale scent”
Sources: lovi.care, sephora.com, ulta.com, beautybay.com, cultbeauty.com, spacenk.com, and more
Questions and answers
How well does The Ordinary Retinol 0.5% in Squalane work for oily acne-prone skin?
This product works fairly well for your oily skin by offering visible anti-aging effects, but it lacks targeted ingredients to address blemishes and breakouts. To truly fit oily and acne-prone skin, a treatment needs ingredients like niacinamide, propolis, or vitamin C to help with oil control and breakouts without feeling heavy.
Which ingredients make this treatment a good fit for oily acne-prone skin?
Retinol makes this treatment a good fit by helping smooth and clear oily skin, while squalane gives lightweight moisture without feeling heavy. To truly suit oily and acne-prone skin, a product of this type needs targeted ingredients like niacinamide or vitamin C to tackle blemishes and control excess oil.
What does Retinol do for oily acne-prone skin?
Retinol helps oily acne-prone skin by clearing up breakouts and smoothing the skin, though it may occasionally cause some mild scaling or stinging. This ingredient works by addressing the root causes of acne, making it a reliable choice for keeping pores clear and skin smooth.
American Journal of Clinical Dermatology, 2019Journal of Drugs in Dermatology, 2018
What does Squalane do for oily acne-prone skin?
Squalane may help keep oily skin soft and smooth, but oxidized squalene can trigger inflammation in acne-prone skin. Because of this, oily acne-prone skin needs lightweight, non-greasy ingredients that balance moisture without clogging pores.
Where does this treatment go in a skincare routine for oily acne-prone skin?
This treatment goes in the evening routine after cleansing and toning, followed by a moisturizer. Oily acne-prone skin needs a treatment with targeted blemish-fighting ingredients to help clear breakouts.
Can I use this treatment with vitamin C, and in what order?
You can use this treatment with vitamin C by applying vitamin C in the morning and this treatment at night, or by using them on alternate nights to keep your skin calm. Oily acne-prone skin needs a product of this type that also includes targeted blemish-fighting ingredients to properly clear breakouts.
How often should I use this treatment?
Use this treatment in the evening, starting once a week and slowly increasing the frequency if your skin tolerates it well. This routine step helps smooth your skin safely, though this specific formula lacks targeted ingredients for acne and breakouts, so oily acne-prone skin needs added ingredients like salicylic acid or benzoyl peroxide to clear blemishes.
Can this treatment clog pores, cause breakouts or purging for oily acne-prone skin?
Yes, this treatment may cause breakouts for your oily acne-prone skin, as some reviewers frequently report a greasy residue and blemishes. A product of this type needs targeted acne-fighting ingredients like salicylic acid or benzoyl peroxide to properly clear pores and prevent breakouts.
Is this treatment fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle.
International Journal of Cosmetic Science, 2017Clay jojoba oil facial masks reduced total skin lesions by a mean of 54% after 6 weeks in 133 participants with acne-prone, lesioned skin and mild acne compared to baseline.
Forschende Komplementarmedizin, 2012Topical lycopene-based emulgel significantly enhanced skin hydration and elasticity while reducing erythema, melanin, and sebum contents in human volunteers compared to a placebo formulation over 12 weeks.
European Journal of Pharmaceutics and Biopharmaceutics, 2022Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging.
The British Journal of Dermatology, 2019Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity.
Journal of Controlled Release, 2018Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle.
Archives of Dermatological Research, 2017Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025Topical application of an emollient emulsion containing 15.0% caprylic/capric triglyceride doubled the amount of urocanic acid isomers and increased skin hydration with reduced transepidermal water loss in healthy subjects, though it did not prevent ultraviolet-induced urocanic acid isomerization.
Life, 2023Topical application of jojoba wax reduced LPS-induced secretion of IL-6, IL-8, and TNFα by approximately 30% and increased the synthesis of pro-collagen III and hyaluronic acid compared to untreated skin in an ex-vivo human skin organ culture model.
Frontiers in Pharmacology, 2024Topical jojoba oil application in male mice decreased exercise-induced pro-inflammatory gene expression (Il-1b and Il-6 in soleus, Il-1b in gastrocnemius) compared to untreated exercised mice.
Biomolecules, 2025Nanolipidgel formulations with argan or jojoba oil and humectants demonstrate good sensory attributes, instrumental properties, and moisturizing efficacy for cosmetic application.
International Journal of Cosmetic Science, 2014Cosmetic formulations containing lycopene and melatonin showed significant differences in skin sebum content, hydration, elasticity, erythema index, and melanin index compared to control in 36 healthy women.
Skin Pharmacology and Physiology, 2020Topical delivery of lycopene via MG- and TG-containing microemulsions significantly increased stratum corneum and viable skin layer penetration compared to a control solution, with the MG-containing microemulsion also increasing skin antioxidant activity by 10-fold.
Journal of Pharmaceutical Sciences, 2010Tomato-derived nanovesicles and extract accelerated wound closure and increased cell migration in human keratinocytes and mouse fibroblasts without affecting cell proliferation.
International Journal of Molecular Sciences, 2024
Why other serums fit oily acne-prone skin better
A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.
Clinical Pharmacology, 2018Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo.
BioMed Research International, 2022
Ingredients
Squalane, Caprylic Capric Triglyceride, Jojoba Seed Oil, Retinol, Solanum Lycopersicum Fruit Extract Tomato Fruit Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Hydroxymethoxyphenyl Decanone, Bht
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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