🇮🇪Ireland

The Ordinary Multi-Peptide + HA Serum for mature skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

The Ordinary Multi-Peptide + HA Serum

High

  • SuperiorNormal Skin Fit
  • HighEffectiveness
  • ExcellentSafety

A great choice for mature skin; a few serums fit it even better.

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Excellent suitability for your normal skin is provided by multiple peptides like Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1, which effectively target wrinkles and fine lines by stimulating collagen production and enhancing skin elasticity.
  • The inclusion of Glycerin and Sodium Hyaluronate Crosspolymer further supports your skin's hydration and plumping, complementing the firming effects for a smoother appearance.
  • The product is safe for your normal skin, featuring soothing ingredients like Allantoin and Sodium Hyaluronate, with no harsh or prohibited substances.

How to apply

  • Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
  • Apply this serum after your toner and before your moisturizer.
  • Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
  • You can apply the serum on dry skin for the best results against fine lines.
  • Always do a patch test before your first use and avoid the sensitive eye area.

People Say

★4.4Overall rating based on 2.5k+ reviews

Based on a very large amount of data, users with dry, mature, or dehydrated skin frequently praise this serum for its ability to plump the skin and smooth texture, often noting a reduction in fine dehydration lines. While many appreciate it as an affordable "all-in-one" anti-aging solution, a minority of users report breakouts or a lack of visible results regarding deeper wrinkles.

Highlights

  • Deeply hydrates Mostly Mentioned
    • “Surprisingly hydrated my skin very well in the dry mountain air.”
    • “My skin feels more hydrated, smooth, and plump.”
    • “It’s so hydrating for the skin.”
    • “Left my skin feeling very moisturizing.”
  • Great value Often Mentioned
    • “Good quality and good price.”
    • “Buying the 60ml is better value... good value for money.”
    • “Proof you don't need to spend a fortune for good science.”
    • “Affordable and will last you months.”
  • Smooths texture Often Mentioned
    • “It really improved the texture of my skin.”
    • “Left my skin feeling so smooth.”
    • “Noticeably smoother skin in 8 weeks.”
    • “Improves skin smoothness and targets multiple signs of aging.”
  • Plumps and firms Sometimes Noted
    • “Makes my skin feel so firm after use.”
    • “Experience firmer, plumper, and more resilient skin.”
    • “Improves the feel of skin elasticity.”
    • “Skin feels tighter after.”
  • Reduces fine lines Sometimes Noted
    • “I notice less of crows feet after.”
    • “Fine lines around my eyes... look much less prominent.”
    • “Targets dynamic lines and wrinkles.”
    • “Helps significantly improve the appearance of crow's feet.”
  • Conflicts with actives Sometimes Noted
    • “Avoid using direct acids, direct vitamin C... in the same routine.”
    • “Can be complicated to use... peptides and Vitamin C don't play well.”
    • “Hard to fit into my routine due to conflicts.”
    • “Cannot use with my other acid toners.”
  • Unclear results Sometimes Noted
    • “Didn't see exceptional results but good for a basic serum.”
    • “Quite nice feeling but idk what it does honestly.”
    • “Haven't noticed a huge difference in wrinkles yet.”
    • “Good basic serum but don't expect miracles.”
  • Allergic reactions Rarely Noted
    • “My eyes were swollen almost shut the morning after.”
    • “Do not use if you have sensitive skin!!”
    • “Caused a burning sensation immediately.”
    • “Face turned red and itchy.”
  • Causes breakouts Rarely Noted
    • “Some people say Buffet has made their skin break out.”
    • “Worried about this product causing acne.”
    • “Caused small bumps on my forehead.”
    • “My skin broke out after a few days.”

Sources: lovi.care, theordinary.com, sephora.com, ulta.com, amazon.com, deciemchatroom.com, and more

Questions and answers

What makes The Ordinary Multi-Peptide + HA a great fit for mature skin?

This serum is a great fit because its multiple peptides like Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1 help smooth out wrinkles and fine lines by boosting collagen and firmness. Glycerin and Sodium Hyaluronate also support deep hydration to leave your skin looking plumper and smoother.

American Journal of Clinical Dermatology, 2013Annals of Dermatology, 2019

Which ingredients make this serum a good fit for mature skin?

This serum is a great fit for mature skin because it contains multiple peptides like Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1, which target wrinkles and fine lines by boosting collagen and elasticity. Glycerin and Sodium Hyaluronate further support hydration and plumping for a smoother, firmer appearance.

American Journal of Clinical Dermatology, 2013Annals of Dermatology, 2019

What do Peptides do for mature skin?

Peptides help mature skin by triggering signals that encourage collagen production, which supports firmness and smooths the look of fine lines. They may improve skin elasticity and help repair signs of aging, though their effectiveness depends heavily on how well they penetrate the skin surface.

International Journal of Cosmetic Science, 2009Biomolecules, 2025

What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.

Journal of Drugs in Dermatology, 2011Skin Research and Technology, 2024

Where does this serum go in a skincare routine for mature skin?

This serum goes in your evening routine after cleansing and toning, and before your moisturizer. Putting treatments in the evening helps ensure safety around sun exposure.

Can I use it with retinol, and in what order?

You can use this treatment alongside retinol by applying your retinol first, letting it absorb, and then following with this peptide serum. This combination helps smooth fine lines while keeping your skin hydrated, though using active ingredients together may occasionally cause mild tingling.

American Journal of Clinical Dermatology, 2013Annals of Dermatology, 2019

How often should I use this serum?

You can use this treatment in the evening as part of your routine, or twice a day depending on your skin's preference. It helps smooth mature skin by targeting fine lines and boosting hydration.

American Journal of Clinical Dermatology, 2013Annals of Dermatology, 2019

Can it clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to clog pores or cause breakouts on mature skin, as it features soothing ingredients with a very low chance of breakouts. Regular use helps keep your skin smooth and hydrated while targeting fine lines.

American Journal of Clinical Dermatology, 2013Clinical, Cosmetic and Investigational Dermatology, 2017

Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group.

    American Journal of Clinical Dermatology, 2013

  • Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days.

    Annals of Dermatology, 2019

  • Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear.

    Journal of Cosmetic Dermatology, 2017

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017

  • Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine.

    Journal of Pharmacy & Pharmaceutical Sciences, 2015

  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011

  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022

  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019

  • Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy.

    European Journal of Neurology, 2013

  • Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects.

    Journal of Cosmetic and Laser Therapy, 2013

  • Dissolving microneedles loaded with 3-O-ethyl ascorbic acid and acetyl hexapeptide-8 achieved higher cumulative transdermal delivery than aqueous solutions and significantly reduced photoaging signs while restoring oxidative balance in a UV/D-galactose-induced mouse model.

    International Journal of Biological Macromolecules, 2026

  • A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.

    Journal of Cosmetic Dermatology, 2015

  • Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.

    Journal of Cosmetic Dermatology, 2026

  • Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components.

    International Journal of Cosmetic Science, 2026

Ingredients

Water, Glycerin, Lactococcus Lysate Ferment, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium Pca, Pca, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, Ppg-26-Buteth-26, Peg-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Ethoxydiglycol, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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Prices checked 18 Oct – 25 Oct 2026

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

How does it fit your skin?

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