馃嚞馃嚙United Kingdom

ISDIN vs Sesderma

Rated by Lovi 路 Unbiased, science-based skincare AI trained on real user outcomes 路 How the Fit score works

ISDIN and Sesderma are distinguished Spanish skincare brands rooted in decades of dermatological research. The former is known for its sophisticated moisturizers, advanced sunscreens, targeted serums, and soothing eye products, while the latter is recognized for its advanced serums and meticulously engineered formulas. Both brands suit sensitive skin best, with the first also excelling for dry skin and the second favoring hyperpigmented and aging types. They differ primarily in their standout solutions, as the first offers diverse specialized preparations like Fusion Water, Eryfotona Actinica, and K-Ox Eyes, whereas the second relies on active compounds and botanical extracts like Azelac RU Serum to refine skin texture.

ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

puig.combeautymatter.comuploads.puig.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular ISDIN and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular ISDIN vs Sesderma products

Questions and answers

ISDIN or Sesderma: which is better?

ISDIN is the better choice on this page because it offers a much wider range of products that suit sensitive, dry, and acne-prone skin types well. Reviewers frequently praise its ultralight and makeup-friendly sunscreens, though they also note a high price point.

What is the difference between ISDIN and Sesderma?

ISDIN offers a broad selection of products on this page with sunscreens achieving a Superior Lovi fit for sensitive and dry skin, while Sesderma is represented by just one serum.

Which is more affordable, ISDIN or Sesderma?

Reviews often mention a high price point for the products on this page from ISDIN, while no pricing feedback is available for Sesderma.

Which causes fewer breakouts, ISDIN or Sesderma?

ISDIN is the better choice for acne-prone skin because the products on this page achieve High fit levels for that skin type, whereas Sesderma only reaches an Average fit. The ISDIN range helps manage breakouts with formulas like Retinal Intense Serum.

The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007

When were ISDIN and Sesderma founded and who owns them?

ISDIN was founded in 1975 in Spain and is owned by Puig, while Sesderma was founded in 1989 in Spain and is owned by Grupo Sesderma since 2026.

How many products are listed for each brand, and how many of them contain fragrance?

ISDIN has 8 products listed on this page, and 5 of them contain fragrance. Sesderma has 1 product listed on this page, and it contains fragrance.

Which brand offers a Lovi fit level of Superior for dry sensitive skin?

ISDIN offers a Lovi fit level of Superior for dry sensitive skin with products like Eryfotona Actinica and Fusion Water.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.

QR code: get the Lovi app
Download on theApp Store Get it onGoogle Play