Anua NANO RETINOL™ 0.3% + NIACIN RENEWING SERUM for combination skin
Retinol
Niacinamide
Hyaluronic Acid
Panthenol
AllantoinHigh
- HighCombination Skin Fit
- HighEffectiveness
- ExcellentSafety
A great choice for combination skin; a few serums fit it even better.
- Clinical, Cosmetic and Investigational Dermatology, 2017
- International Journal of Cosmetic Science, 2017
This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers high suitability for your combination skin, as niacinamide helps regulate sebum production in oily areas while glycerin provides essential hydration for drier zones.
- The inclusion of retinol and panthenol further supports skin renewal and soothes the skin, addressing concerns like fine lines and promoting a smoother texture.
- This formula is safe for your skin, containing no harsh ingredients and featuring soothing components like niacinamide and panthenol to prevent irritation.
How to apply
- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
People Say
★4.7Overall rating based on 200+ reviewsUsers find this serum to be an excellent gentle introduction to retinol, effectively smoothing skin texture and refining pores with minimal irritation. While improvements to fine lines and blackheads require consistent use, the formula hydrates and plumps the skin, leaving it glowing and moisturized.
Highlights
Gentle & non-irritating Often Mentioned
- “great for beginners”
- “no harsh peeling”
- “mild formula”
- “zero sensitivity”
Improves texture & pores Often Mentioned
- “pores visibly tightened”
- “glass skin texture”
- “smoother complexion”
- “refined skin”
Brightening effect Sometimes Noted
- “fades dark spots”
- “radiant appearance”
- “brightens dullness”
- “even skin tone”
Elegant texture Sometimes Noted
- “absorbs quickly”
- “lightweight feel”
- “non-sticky”
- “layers well”
Hydrating & plumping Sometimes Noted
- “moisturizing finish”
- “non-drying formula”
- “plump and firm”
- “healthy glow”
Slow results Sometimes Noted
- “not instant fix”
- “takes time”
- “requires patience”
- “cumulative effect”
Initial sensitivity Rarely Noted
- “slight tingling”
- “mild purging”
- “minor redness”
- “start slowly”
Scent preferences Rarely Noted
- “medicinal smell”
- “herbal scent”
- “wish it was unscented”
- “smell lingers”
Small quantity Rarely Noted
- “bottle too small”
- “finished quickly”
- “wish for bigger size”
- “30ml not enough”
Sources: lovi.care, anua.us, iherb.com, stylekorean.com, yesstyle.com, stylevana.com, and more
Questions and answers
What makes Anua Nano Retinol 0.3% + Niacin Renewing Serum a great fit for combination skin?
This serum is a great fit for your combination skin because niacinamide helps balance oil in slick areas while glycerin delivers hydration to dry zones. Retinol and panthenol also support skin renewal and keep your face calm and smooth.
Which ingredients make this serum a good fit for combination skin?
Niacinamide and glycerin make this serum a great fit for combination skin by balancing oily spots and hydrating drier zones. Retinol and panthenol also help renew the skin and keep it smooth and calm.
What does Retinol do for combination skin?
Retinol helps smooth fine lines, even out skin tone, and improve firmness in combination skin. It works by encouraging faster skin renewal and boosting collagen, though it may occasionally cause mild dryness or scaling while your skin adjusts.
What does Niacinamide do for combination skin?
Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Where does this serum go in a skincare routine for combination skin?
Apply this serum in your evening routine, using it after cleansing and before your moisturizer. Putting treatments in the evening helps keep things simple and gives you extra safety around sun exposure.
Can I use this serum with vitamin C, and in what order?
You can use this serum with vitamin C by applying vitamin C in your morning routine and this treatment serum at night, as using them at different times helps prevent irritation. This formula is safe for your skin, featuring soothing components like niacinamide and panthenol.
How often should I use this serum?
This treatment serum works best in your evening routine, starting at once a week and gradually building up frequency as your skin feels comfortable. This gentle approach helps prevent irritation while supporting smoother texture and renewal over time.
Can this serum clog pores, cause breakouts or purging for combination skin?
This serum is unlikely to cause clogged pores or breakouts on combination skin because niacinamide helps balance oil production while soothing ingredients prevent irritation. However, because it contains retinol, you may experience mild initial purging or sensitivity as it speeds up skin renewal.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle.
International Journal of Cosmetic Science, 2017Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.
American Journal of Clinical Dermatology, 2002Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging.
The British Journal of Dermatology, 2019Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity.
Journal of Controlled Release, 2018Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle.
Archives of Dermatological Research, 2017Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.
Arzneimittel-Forschung, 2000Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.
Auris, Nasus, Larynx, 2020Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.
Aesthetic Plastic Surgery, 2018
Ingredients
Water, Niacinamide, Glycerin, Butylene Glycol, 1,2-Hexanediol, Panthenol, Hyaluronic Acid, Allantoin, Betaine, Tocopherol, Ethylhexylglycerin, Adenosine, Caprylyl Glycol, Xanthan Gum, Disodium Edta
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.