iS Clinical skincare
iS Clinical is an American skincare brand founded in 2000 and owned by Science of Skincare, LLC.
isclinicalskincare.co.zaisclinical.comisclinical.ietracxn.com
iS Clinical is beloved for its sophisticated serums, moisturizers, cleansers, and eye products, all driven by meticulously crafted formulas. Its products suit oily acne-prone skin and oily skin best because of their targeted botanical designs. The standout products for specific concerns include the Cleansing Complex for acne-prone skin, the Super Serum Advance+ for skin with dark spots, and the Youth Eye Complex for mature skin. Through these carefully balanced formulations, the brand delivers reliable botanical support that elevates daily routines.
This page covers some of the most popular iS Clinical products; for the whole iS Clinical range, with a fit score for every product, use the Lovi app.
People Say
★4.7Overall rating based on 4.4k+ reviewsReviewers most often praise iS Clinical for gentle hydration, effective acne management, and lightweight textures. The most common complaints are high price points and insufficient hydration for dry skin.
Highlights
Lightweight, non-greasy moisturizers Mostly Mentioned
- “Absorbs beautifully — Reparative Moisture Emulsion”
- “Drink of water — Hydra-Cool Serum”
Texture-improving serums Mostly Mentioned
- “skin feels softer — Active Serum”
- “Fades acne scars — Super Serum Advance+”
Anti-aging serums Often Mentioned
- “Reduces fine lines — Super Serum Advance+”
- “softens fine lines — Active Serum”
Non-irritating serums Often Mentioned
- “Good for sensitive skin — Super Serum Advance+”
- “It is not oily or pore clogging and hasn't irritated my acne prone skin. — Brightening Complex”
High price point Mostly Mentioned
- “expensive for small bottle — Active Serum”
- “Definitely pricey — Reparative Moisture Emulsion”
- “Just expensive — Hydra-Cool Serum”
Sources: lovi.care, dermstore.com, lovelyskin.com, bluemercury.com, spacenk.com, walmart.com, and more
Questions and answers
Is iS Clinical good for oily skin?
Yes, iS Clinical is good for oily skin, and Lovi rates the brand-focused routine Superior for oily skin. The iS Clinical products on this page help keep skin lightweight and non-greasy.
Is iS Clinical worth it?
iS Clinical products are often considered pricey by reviewers, yet Lovi rates the brand-focused routines High for dry skin and Superior for oily and sensitive skin. The iS Clinical products on this page are lightweight and fragrance-free.
What are iS Clinical's best products?
Which iS Clinical moisturizer is best for dry skin?
The best moisturizer for dry skin is Hydra-Cool Serum, with Reparative Moisture Emulsion also acting as a strong option. Lovi rates both products High for dry skin.
Does iS Clinical cause breakouts?
iS Clinical is unlikely to cause breakouts, as the iS Clinical products on this page help keep pores clear with texture-improving serums like Active Serum. Lovi rates the acne-prone skin fit High for Cleansing Complex and Active Serum.
Is iS Clinical fragrance-free?
Yes, the iS Clinical products on this page list no fragrance in their ingredients. This helps keep the formulas gentle for everyday use.
What are the key ingredients in iS Clinical products?
Hyaluronic acid is a key ingredient featured across the iS Clinical products on this page. Topical hyaluronic acid helps improve skin quality and signs of skin aging.
How do I build a iS Clinical skincare routine?
To build an iS Clinical routine for dry skin in the morning, apply Cleansing Complex followed by Hydra-Cool Serum. In the evening, use Ultra Hyalon Cleansing Cream, Cleansing Complex, 1025 Dokdo Cleansing Water, Super Serum Advance+, and Hydra-Cool Serum. Once a week, add Cica Mild Powder Wash and Watermide Essential Mask to that evening routine.
Dermatologic Therapy, 2022Journal of Cosmetic Dermatology, 2020
Where can I buy iS Clinical, and how much does it cost?
iS Clinical products can be bought in stores in the United Arab Emirates. Prices on the page range from AED 138.20 to AED 553.25, with most falling between AED 305.07 and AED 496.51.
What are good alternatives to iS Clinical?
Good alternatives to iS Clinical on Lovi include brands like CeraVe, Cetaphil, Paula's Choice, Neutrogena, Kiehl's, and Dermalogica. These similar skincare brands offer alternative options for various skin types and routines.
iS Clinical vs CeraVe: which is better?
iS Clinical and CeraVe both rate High for dry skin and Superior for combination skin, oily skin, sensitive skin, and acne-prone skin, so neither brand is universally better than the other. Reviewers note that iS Clinical offers texture-improving serums and lightweight moisturizers at a high price point.
Who owns iS Clinical, and where is it from?
iS Clinical is an American brand founded in 2000, owned by Science of Skincare, LLC.
isclinicalskincare.co.zaisclinical.comisclinical.ietracxn.com
Is iS Clinical cruelty-free?
PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list iS Clinical as cruelty-free.
Is iS Clinical good for dry skin?
iS Clinical is a good match for dry skin, and Lovi rates the iS Clinical-focused routine High for dry skin. The iS Clinical products on this page help keep dry skin soft and smooth with ingredients like hyaluronic acid.
Which iS Clinical cleanser is best for oily skin?
Cleansing Complex is the best choice for oily skin, as Lovi rates it Superior for this skin type.
Is iS Clinical good for sensitive skin?
Yes, iS Clinical is a great fit for sensitive skin, as Lovi rates the brand-focused routine Superior for this skin type. Reviewers often mention that the serums are non-irritating.
Is iS Clinical good for acne-prone skin?
Yes, iS Clinical fits acne-prone skin well, as Lovi rates the brand-focused routine Superior for this skin type. The iS Clinical products on this page help calm and clear the skin.
Is iS Clinical good for skin with dark spots?
Yes, iS Clinical is good for skin with dark spots because Lovi rates Cleansing Complex, Active Serum, Hydra-Cool Serum, Super Serum Advance+, and Youth Eye Complex High for skin with dark spots. The iS Clinical products on this page help brighten the complexion and improve texture.
Journal of Cosmetic Dermatology, 2020Journal of Cosmetic Dermatology, 2020
Is iS Clinical good for mature skin?
Yes, iS Clinical is good for mature skin, and Lovi rates Youth Eye Complex and Cleansing Complex Superior for this skin type, with Super Serum Advance+, Reparative Moisture Emulsion, and Youth Eye Complex also functioning as anti-aging serums that reviewers often mention. Hyaluronic acid helps improve skin quality and signs of aging.
Dermatologic Therapy, 2022Journal of Cosmetic Dermatology, 2020
Research behind iS Clinical's key ingredients
Effects of menthol and cold on histamine-induced itch and skin reactions in man
Psychophysical study of the effects of topical application of menthol in healthy volunteers
Combination of microneedling and glycolic acid peels for the treatment of acne scars in dark skin
Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study
Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind these ratings
Lovi rates every product from its full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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