🇫🇷France

iS Clinical skincare

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

iS Clinical is an American skincare brand founded in 2000 and owned by Science of Skincare, LLC.

isclinicalskincare.co.zaisclinical.comisclinical.ietracxn.com

iS Clinical is beloved for its sophisticated serums, moisturizers, cleansers, and eye products, all driven by meticulously crafted formulas. Its products suit oily acne-prone skin and oily skin best because of their targeted botanical designs. The standout products for specific concerns include the Cleansing Complex for acne-prone skin, the Super Serum Advance+ for skin with dark spots, and the Youth Eye Complex for mature skin. Through these carefully balanced formulations, the brand delivers reliable botanical support that elevates daily routines.

This page covers some of the most popular iS Clinical products; for the whole iS Clinical range, with a fit score for every product, use the Lovi app.

Other iS Clinical products

People Say

★4.7Overall rating based on 4.4k+ reviews

Reviewers most often praise iS Clinical for gentle hydration, effective acne management, and lightweight textures. The most common complaints are high price points and insufficient hydration for dry skin.

Highlights

  • Lightweight, non-greasy moisturizers Mostly Mentioned
    • “Absorbs beautifully — Reparative Moisture Emulsion”
    • “Drink of water — Hydra-Cool Serum”
  • Texture-improving serums Mostly Mentioned
    • “skin feels softer — Active Serum”
    • “Fades acne scars — Super Serum Advance+”
  • Anti-aging serums Often Mentioned
    • “Reduces fine lines — Super Serum Advance+”
    • “softens fine lines — Active Serum”
  • Non-irritating serums Often Mentioned
    • “Good for sensitive skin — Super Serum Advance+”
    • “It is not oily or pore clogging and hasn't irritated my acne prone skin. — Brightening Complex”
  • High price point Mostly Mentioned
    • “expensive for small bottle — Active Serum”
    • “Definitely pricey — Reparative Moisture Emulsion”
    • “Just expensive — Hydra-Cool Serum”

Sources: lovi.care, dermstore.com, lovelyskin.com, bluemercury.com, spacenk.com, walmart.com, and more

Questions and answers

Is iS Clinical good for oily skin?

Yes, iS Clinical is well suited for oily skin, as Lovi rates the brand-focused routine Superior for this skin type. Reviewers mostly mention that the moisturizers are lightweight and non-greasy.

Is iS Clinical worth it?

Deciding if iS Clinical is worth it depends on your budget, as the brand features a high price point. Reviewers often mention lightweight moisturizers and smoothing serums, and Lovi rates the brand-focused routines Superior for dry, oily, sensitive, combination, and acne-prone skin.

What are iS Clinical's best products?

iS Clinical features standout products like Cleansing Complex and Youth Eye Complex, which Lovi rates Superior for several skin types. Reviewers often mention its texture-improving serums and lightweight, non-greasy moisturizers.

Which iS Clinical moisturizer is best for dry skin?

The best moisturizer for dry skin is Hydra-Cool Serum, with Reparative Moisture Emulsion also offering strong support. Lovi rates both High for dry skin.

Does iS Clinical cause breakouts?

iS Clinical is unlikely to cause breakouts, as the brand features non-irritating serums and lightweight, non-greasy moisturizers. Lovi rates Cleansing Complex and Active Serum High for acne-prone skin.

Is iS Clinical fragrance-free?

Yes, every one of the iS Clinical products on this page lists no fragrance in its ingredients.

What are the key ingredients in iS Clinical products?

The key ingredient in iS Clinical products is hyaluronic acid, which helps keep skin hydrated and smooth. Lovi rates the brand's products high for delivering this moisture benefit.

Dermatologic Therapy, 2022

Where can I buy iS Clinical, and how much does it cost?

You can buy iS Clinical at stores in France. Prices on the page range from €67.02 to €267.50, with most falling between €204.50 and €228.50.

What are good alternatives to iS Clinical?

Good alternatives to iS Clinical include brands with pages on Lovi like CeraVe, Cetaphil, Paula's Choice, Neutrogena, Kiehl's, and Dermalogica. Lovi rates the CeraVe-focused routine as High for dry skin and sensitive skin, and Superior for oily, combination, and acne-prone skin.

iS Clinical vs CeraVe: which is better?

iS Clinical is better for dry skin, oily skin, sensitive skin, and combination skin, where Lovi rates the iS Clinical-focused routine Superior compared to CeraVe. For acne-prone skin, both brands tie with a Superior fit level on Lovi. Reviewers often mention that iS Clinical offers texture-improving and anti-aging serums, though the brand has a high price point.

Who owns iS Clinical, and where is it from?

iS Clinical is an American brand founded in 2000, owned by Science of Skincare, LLC.

isclinicalskincare.co.zaisclinical.comisclinical.ietracxn.com

Is iS Clinical cruelty-free?

PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list iS Clinical as cruelty-free.

Is iS Clinical good for dry skin?

iS Clinical is a good choice for dry skin, and Lovi rates the iS Clinical-focused routine Superior for dry skin. The brand offers products like Super Serum Advance+ and Hydra-Cool Serum to help hydrate dry skin.

Dermatologic Therapy, 2022

Which iS Clinical cleanser is best for oily skin?

Cleansing Complex is the best cleanser on this page for oily skin, where Lovi rates it Superior.

Is iS Clinical good for sensitive skin?

Yes, iS Clinical is well suited for sensitive skin, as Lovi rates the brand-focused routine Superior for this skin type. Reviewers frequently note that the serums are non-irritating, and the iS Clinical products on this page list no fragrance in their ingredients.

Is iS Clinical good for acne-prone skin?

Yes, iS Clinical is well suited for acne-prone skin, as Lovi rates its brand-focused routine Superior for this skin type. Reviewers often mention its texture-improving serums, and the iS Clinical products on this page list no fragrance.

Is iS Clinical good for skin with dark spots?

Yes, iS Clinical is good for skin with dark spots because several of its serums and moisturizers, such as Active Serum and Super Serum Advance+, rate High for skin with dark spots. Reviewers often mention that these texture-improving serums help smooth the skin.

Journal of Cosmetic Dermatology, 2020Journal of Cosmetic Dermatology, 2020

Is iS Clinical good for mature skin?

Yes, iS Clinical is a good option for mature skin, as Lovi rates products like Youth Eye Complex Superior and Reparative Moisture Emulsion High for this skin type. Reviewers often mention the anti-aging serums, which help smooth and firm the skin.

Dermatologic Therapy, 2022

Research behind iS Clinical's key ingredients

Behind these ratings

Lovi rates every product from its full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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