iS Clinical skincare
iS Clinical is an American skincare brand founded in 2000 and owned by Science of Skincare, LLC.
isclinicalskincare.co.zaisclinical.comisclinical.ietracxn.com
Skincare enthusiasts love iS Clinical for its targeted serums, nourishing moisturizers, gentle cleansers, and restorative eye products, which are driven by advanced formulas. Its products suit oily acne-prone skin and combination skin best, owing to these carefully balanced formulations. For specific concerns, the Cleansing Complex addresses acne-prone skin, the Super Serum Advance+ targets skin with dark spots, and the Youth Eye Complex cares for mature skin. Each offering works harmoniously to support overall skin health and radiance.
This page covers some of the most popular iS Clinical products; for the whole iS Clinical range, with a fit score for every product, use the Lovi app.
People Say
★4.7Overall rating based on 4.4k+ reviewsReviewers most often praise iS Clinical for gentle hydration, effective acne management, and lightweight textures. The most common complaints are high price points and insufficient hydration for dry skin.
Highlights
Lightweight, non-greasy moisturizers Mostly Mentioned
- “Absorbs beautifully — Reparative Moisture Emulsion”
- “Drink of water — Hydra-Cool Serum”
Texture-improving serums Mostly Mentioned
- “skin feels softer — Active Serum”
- “Fades acne scars — Super Serum Advance+”
Anti-aging serums Often Mentioned
- “Reduces fine lines — Super Serum Advance+”
- “softens fine lines — Active Serum”
Non-irritating serums Often Mentioned
- “Good for sensitive skin — Super Serum Advance+”
- “It is not oily or pore clogging and hasn't irritated my acne prone skin. — Brightening Complex”
High price point Mostly Mentioned
- “expensive for small bottle — Active Serum”
- “Definitely pricey — Reparative Moisture Emulsion”
- “Just expensive — Hydra-Cool Serum”
Sources: lovi.care, dermstore.com, lovelyskin.com, bluemercury.com, spacenk.com, walmart.com, and more
Questions and answers
Is iS Clinical good for oily skin?
Yes, iS Clinical is good for oily skin. Lovi rates the brand-focused routine for oily skin as Superior. Reviewers mostly mention that the iS Clinical products on this page include lightweight, non-greasy moisturizers.
Is iS Clinical worth it?
iS Clinical is often considered worth it for shoppers seeking texture-improving and anti-aging serums, though reviewers frequently mention a high price point. Lovi rates the brand-focused routine Superior for dry skin, oily skin, sensitive skin, combination skin, and acne-prone skin. The iS Clinical products on this page list no fragrance in their ingredients.
What are iS Clinical's best products?
iS Clinical features products with superior fits across various concerns, such as Cleansing Complex for oily and sensitive skin, Super Serum Advance+ for dry skin, and Youth Eye Complex for mature skin. Reviewers often mention its texture-improving serums and lightweight, non-greasy moisturizers.
Dermatologic Therapy, 2022Journal of Cosmetic Dermatology, 2020
Which iS Clinical moisturizer is best for dry skin?
Hydra-Cool Serum is best for dry skin, and Reparative Moisture Emulsion is another option. Lovi rates both High for dry skin.
Does iS Clinical cause breakouts?
iS Clinical is unlikely to cause breakouts, as the iS Clinical products on this page are non-greasy and the brand offers options like Cleansing Complex that fit acne-prone skin well.
Is iS Clinical fragrance-free?
Yes, every one of the iS Clinical products on this page lists no fragrance in its ingredients.
What are the key ingredients in iS Clinical products?
The key ingredient across the iS Clinical products on this page is hyaluronic acid, which helps keep the skin hydrated and smooth. Hyaluronic acid is commonly used in skincare to improve overall skin quality and address signs of aging.
How do I build a iS Clinical skincare routine?
To build an iS Clinical routine for dry skin in the morning, use Cleansing Complex, Propolis Synergy Toner, Hydra-Cool Serum, and Safe Sunscreen SPF 50+. In the evening, use Ultra Hyalon Cleansing Cream, Cleansing Complex, Super Serum Advance+, and Hydra-Cool Serum. Once a week, add Collagen Essential Mask after the cleansers before applying your serum and moisturizer.
Dermatologic Therapy, 2022Journal of Cosmetic Dermatology, 2020
Where can I buy iS Clinical, and how much does it cost?
iS Clinical is available on this page with stores in Singapore, and prices range from S$68.81 to S$175.53 with most falling between S$98.30 and S$151.69.
What are good alternatives to iS Clinical?
Good alternatives to iS Clinical on Lovi include CeraVe, Cetaphil, Paula's Choice, Neutrogena, Kiehl's, and Dermalogica. These similar skincare brands offer alternative options for various skin types and routines.
iS Clinical vs CeraVe: which is better?
Lovi rates the iS Clinical-focused routines Superior for dry, oily, sensitive, combination, and acne-prone skin, while CeraVe routines rate High for dry, oily, and combination skin, and Superior for sensitive and acne-prone skin.
Who owns iS Clinical, and where is it from?
iS Clinical is an American brand founded in 2000, owned by Science of Skincare, LLC.
isclinicalskincare.co.zaisclinical.comisclinical.ietracxn.com
Is iS Clinical cruelty-free?
PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list iS Clinical as cruelty-free.
Is iS Clinical good for dry skin?
Yes, iS Clinical is well suited for dry skin, and Lovi rates the iS Clinical-focused routine Superior for dry skin. Reviewers often mention that the moisturizers are lightweight and non-greasy, which helps keep dry skin feeling soft and comfortable.
Which iS Clinical cleanser is best for oily skin?
Cleansing Complex is the best choice for oily skin, as Lovi rates it Superior for that skin type.
Is iS Clinical good for sensitive skin?
Yes, iS Clinical is well suited for sensitive skin, and Lovi rates the brand-focused routine Superior for sensitive skin. Reviewers note that the serums are non-irritating.
Is iS Clinical good for acne-prone skin?
Yes, iS Clinical is good for acne-prone skin because the brand-focused routine for this skin type rates Superior on Lovi. Cleansing Complex and Active Serum help improve skin texture and manage breakouts.
Is iS Clinical good for skin with dark spots?
Yes, iS Clinical offers several products that help with skin that has dark spots, such as Cleansing Complex, Active Serum, Super Serum Advance+, and Youth Eye Complex, which all rate High for that skin type.
Dermatologic Therapy, 2022Journal of Cosmetic Dermatology, 2020
Is iS Clinical good for mature skin?
Yes, iS Clinical is good for mature skin. Lovi rates Youth Eye Complex Superior and Super Serum Advance+ High for mature skin, alongside several other products rated High. Reviewers often mention the anti-aging serums.
Journal of Cosmetic Dermatology, 2020Dermatologic Therapy, 2022
Research behind iS Clinical's key ingredients
Effects of menthol and cold on histamine-induced itch and skin reactions in man
Psychophysical study of the effects of topical application of menthol in healthy volunteers
Combination of microneedling and glycolic acid peels for the treatment of acne scars in dark skin
Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study
Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind these ratings
Lovi rates every product from its full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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