🇮🇪Ireland

iS Clinical skincare

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

iS Clinical is an American skincare brand founded in 2000 and owned by Science of Skincare, LLC.

isclinicalskincare.co.zaisclinical.comisclinical.ietracxn.com

Skincare enthusiasts love iS Clinical for its targeted serums, nourishing moisturizers, gentle cleansers, and restorative eye products, all powered by meticulously crafted formulas. Its products suit oily skin and oily acne-prone skin best, helping to balance and refine the complexion. For specific concerns, the Cleansing Complex addresses acne-prone skin, the Super Serum Advance+ targets dark spots, and the Youth Eye Complex cares for mature skin. Through these refined offerings, the brand delivers thoughtful results with reliable precision.

This page covers some of the most popular iS Clinical products; for the whole iS Clinical range, with a fit score for every product, use the Lovi app.

Other iS Clinical products

People Say

★4.7Overall rating based on 4.4k+ reviews

Reviewers most often praise iS Clinical for gentle hydration, effective acne management, and lightweight textures. The most common complaints are high price points and insufficient hydration for dry skin.

Highlights

  • Lightweight, non-greasy moisturizers Mostly Mentioned
    • “Absorbs beautifully — Reparative Moisture Emulsion”
    • “Drink of water — Hydra-Cool Serum”
  • Texture-improving serums Mostly Mentioned
    • “skin feels softer — Active Serum”
    • “Fades acne scars — Super Serum Advance+”
  • Anti-aging serums Often Mentioned
    • “Reduces fine lines — Super Serum Advance+”
    • “softens fine lines — Active Serum”
  • Non-irritating serums Often Mentioned
    • “Good for sensitive skin — Super Serum Advance+”
    • “It is not oily or pore clogging and hasn't irritated my acne prone skin. — Brightening Complex”
  • High price point Mostly Mentioned
    • “expensive for small bottle — Active Serum”
    • “Definitely pricey — Reparative Moisture Emulsion”
    • “Just expensive — Hydra-Cool Serum”

Sources: lovi.care, dermstore.com, lovelyskin.com, bluemercury.com, spacenk.com, walmart.com, and more

Questions and answers

Is iS Clinical good for oily skin?

Yes, iS Clinical is well suited for oily skin, as Lovi rates the brand-focused routine Superior for this skin type. Reviewers mostly mention that the moisturizers are lightweight and non-greasy, and the products on this page list no fragrance.

Is iS Clinical worth it?

Deciding if iS Clinical is worth it depends on your budget, as the products on the page carry high prices starting at ninety-five euros. Reviewers often mention lightweight moisturizers and texture-improving serums, and Lovi rates the brand-focused routine High for dry skin and Superior for oily skin.

What are iS Clinical's best products?

iS Clinical fits oily skin and oily acne-prone skin best, and Lovi rates Cleansing Complex Superior for both skin types. Youth Eye Complex is also a top choice, as Lovi rates it Superior for mature skin.

Which iS Clinical moisturizer is best for dry skin?

Hydra-Cool Serum is the best iS Clinical moisturizer for dry skin, as Lovi rates it High for dry skin, followed by Reparative Moisture Emulsion which also rates High.

Does iS Clinical cause breakouts?

iS Clinical is unlikely to cause breakouts, and Lovi rates acne-prone skin Superior for Cleansing Complex, Super Serum Advance+, Youth Eye Complex, and Active Serum. Reviewers mostly mention that these products are lightweight and non-greasy, which helps keep pores clear.

Is iS Clinical fragrance-free?

Yes, every one of the iS Clinical products on this page lists no fragrance in its ingredients.

What are the key ingredients in iS Clinical products?

Hyaluronic acid is a key ingredient featured across the iS Clinical products on this page.

Dermatologic Therapy, 2022

How do I build a iS Clinical skincare routine?

To build an iS Clinical routine for dry skin, start your morning with Cleansing Complex, Propolis Synergy Toner, Advanced Ceramide Lift and Firm Night Cream, and Safe Sunscreen SPF 50+. In the evening, use Ultra Hyalon Cleansing Cream, Cleansing Complex, Active Serum, and Advanced Ceramide Lift and Firm Night Cream. Once a week, add Watermide Essential Mask to this evening routine.

Where can I buy iS Clinical, and how much does it cost?

You can buy iS Clinical at stores in Ireland listed on Lovi, where prices range from €95.00 to €210.00.

What are good alternatives to iS Clinical?

Good alternatives to iS Clinical include CeraVe, Cetaphil, Paula's Choice, Neutrogena, Kiehl's, and Dermalogica, which all have dedicated pages on Lovi.

iS Clinical vs CeraVe: which is better?

iS Clinical and CeraVe both achieve High to Superior fit levels depending on the skin type, with iS Clinical rating Superior for oily, sensitive, combination, and acne-prone skin, and High for dry skin. Reviewers often mention that iS Clinical offers lightweight moisturizers and texture-improving serums, though at a high price point.

Who owns iS Clinical, and where is it from?

iS Clinical is an American brand founded in 2000, owned by Science of Skincare, LLC.

isclinicalskincare.co.zaisclinical.comisclinical.ietracxn.com

Is iS Clinical cruelty-free?

PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list iS Clinical as cruelty-free.

Is iS Clinical good for dry skin?

iS Clinical is a good choice for dry skin, and Lovi rates the brand-focused routine High for dry skin. The iS Clinical products on this page help add moisture with ingredients like hyaluronic acid, which helps improve skin quality.

Dermatologic Therapy, 2022

Which iS Clinical cleanser is best for oily skin?

Cleansing Complex is the best option, as Lovi rates it Superior for oily skin.

Is iS Clinical good for sensitive skin?

Yes, iS Clinical is good for sensitive skin, as Lovi rates Cleansing Complex Superior, and Hydra-Cool Serum and Youth Eye Complex High for sensitive skin. The iS Clinical products on this page list no fragrance in their ingredients.

Is iS Clinical good for acne-prone skin?

Yes, iS Clinical is good for acne-prone skin, and Lovi rates the brand-focused routine Superior for this skin type. The iS Clinical products on this page help clear and smooth blemish-prone complexions while keeping skin soft.

Journal of Cosmetic Dermatology, 2011International Journal of Nanomedicine, 2021

Is iS Clinical good for skin with dark spots?

Yes, iS Clinical is good for skin with dark spots, as the iS Clinical products on this page help improve tone and texture. Lovi rates Cleansing Complex, Active Serum, Hydra-Cool Serum, Super Serum Advance+, and Youth Eye Complex High for skin with dark spots. Hyaluronic acid helps hydrate the skin while these serums address uneven tone.

Dermatologic Therapy, 2022Journal of Cosmetic Dermatology, 2020

Is iS Clinical good for mature skin?

Yes, iS Clinical is good for mature skin. Lovi rates the Cleansing Complex, Reparative Moisture Emulsion, Super Serum Advance+, Youth Eye Complex, and Brightening Complex High for mature skin.

Research behind iS Clinical's key ingredients

Behind these ratings

Lovi rates every product from its full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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