🇸🇦Saudi Arabia

iS Clinical skincare

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

iS Clinical is an American skincare brand founded in 2000 and owned by Science of Skincare, LLC.

isclinicalskincare.co.zaisclinical.comisclinical.ietracxn.com

iS Clinical is beloved for its sophisticated serums, moisturizers, cleansers, and eye products, all driven by meticulously crafted formulas. Its products suit oily acne-prone skin and oily skin best because of their targeted botanical designs. The standout products for specific concerns include the Cleansing Complex for acne-prone skin, the Super Serum Advance+ for skin with dark spots, and the Youth Eye Complex for mature skin. Through these carefully balanced formulations, the brand delivers reliable botanical support that elevates daily routines.

This page covers some of the most popular iS Clinical products; for the whole iS Clinical range, with a fit score for every product, use the Lovi app.

Other iS Clinical products

People Say

★4.7Overall rating based on 4.4k+ reviews

Reviewers most often praise iS Clinical for gentle hydration, effective acne management, and lightweight textures. The most common complaints are high price points and insufficient hydration for dry skin.

Highlights

  • Lightweight, non-greasy moisturizers Mostly Mentioned
    • “Absorbs beautifully — Reparative Moisture Emulsion”
    • “Drink of water — Hydra-Cool Serum”
  • Texture-improving serums Mostly Mentioned
    • “skin feels softer — Active Serum”
    • “Fades acne scars — Super Serum Advance+”
  • Anti-aging serums Often Mentioned
    • “Reduces fine lines — Super Serum Advance+”
    • “softens fine lines — Active Serum”
  • Non-irritating serums Often Mentioned
    • “Good for sensitive skin — Super Serum Advance+”
    • “It is not oily or pore clogging and hasn't irritated my acne prone skin. — Brightening Complex”
  • High price point Mostly Mentioned
    • “expensive for small bottle — Active Serum”
    • “Definitely pricey — Reparative Moisture Emulsion”
    • “Just expensive — Hydra-Cool Serum”

Sources: lovi.care, dermstore.com, lovelyskin.com, bluemercury.com, spacenk.com, walmart.com, and more

Questions and answers

Is iS Clinical good for oily skin?

Yes, iS Clinical is good for oily skin because the brand-focused routine rates Superior for this skin type. Products like Cleansing Complex and Active Serum help keep oily skin clear and smooth. Lovi rates Cleansing Complex and Active Serum High for oily skin.

Is iS Clinical worth it?

iS Clinical may be worth it for shoppers looking for lightweight moisturizers and texture-improving serums, though the brand has a high price point. Lovi rates the brand-focused routines High for dry skin and Superior for oily, sensitive, combination, and acne-prone skin.

What are iS Clinical's best products?

iS Clinical's best products are Cleansing Complex, Active Serum, Reparative Moisture Emulsion, Hydra-Cool Serum, Super Serum Advance+, Youth Eye Complex, and Brightening Complex, which fit the brand-focused routines best for oily, acne-prone, and combination skin.

Which iS Clinical moisturizer is best for dry skin?

Hydra-Cool Serum is best for dry skin, followed by Reparative Moisture Emulsion. Lovi rates both High for dry skin.

Does iS Clinical cause breakouts?

iS Clinical is unlikely to cause breakouts, as the iS Clinical products on this page help keep oily and acne-prone skin clear with lightweight, non-greasy moisturizers and texture-improving serums. Lovi rates Cleansing Complex and Active Serum High for acne-prone skin.

Is iS Clinical fragrance-free?

Yes, every one of the iS Clinical products on this page lists no fragrance in its ingredients.

What are the key ingredients in iS Clinical products?

The key ingredient across the iS Clinical products on this page is hyaluronic acid. Topical hyaluronic acid helps improve skin quality and signs of skin aging.

Dermatologic Therapy, 2022

How do I build a iS Clinical skincare routine?

To build an iS Clinical routine for dry skin, start your morning with Cleansing Complex, follow with Hydra-Cool Serum, and finish with a sunscreen. In the evening, cleanse with Cleansing Complex, apply Super Serum Advance+, and moisturize with Hydra-Cool Serum. Once a week, add an exfoliating powder and a nourishing mask into your cleansing steps before using Super Serum Advance+ and Hydra-Cool Serum.

Dermatologic Therapy, 2022Journal of Cosmetic Dermatology, 2020

Where can I buy iS Clinical, and how much does it cost?

iS Clinical is available for purchase at stores in Saudi Arabia. The prices for the products on this page range from SAR 241.37 to SAR 589.01, with most items costing between SAR 285.91 and SAR 469.00.

What are good alternatives to iS Clinical?

CeraVe, Cetaphil, Paula's Choice, Neutrogena, Kiehl's, and Dermalogica are similar brands with pages on Lovi.

iS Clinical vs CeraVe: which is better?

CeraVe rates slightly better for dry skin, acne-prone skin, and combination skin, whereas iS Clinical rates slightly better for sensitive skin. Both brands tie for oily skin with a Superior fit.

Who owns iS Clinical, and where is it from?

iS Clinical is an American brand founded in 2000, owned by Science of Skincare, LLC.

isclinicalskincare.co.zaisclinical.comisclinical.ietracxn.com

Is iS Clinical cruelty-free?

PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list iS Clinical as cruelty-free.

Is iS Clinical good for dry skin?

Lovi rates the iS Clinical-focused routine High for dry skin. Super Serum Advance+ rates Superior for dry skin, and Hydra-Cool Serum and Reparative Moisture Emulsion rate High for dry skin.

Dermatologic Therapy, 2022

Which iS Clinical cleanser is best for oily skin?

Cleansing Complex is the best for oily skin, where Lovi rates it Superior.

Is iS Clinical good for sensitive skin?

Yes, iS Clinical fits sensitive skin well because the iS Clinical products on this page list no fragrance in their ingredients. Lovi rates the iS Clinical-focused routine Superior for sensitive skin.

Is iS Clinical good for acne-prone skin?

Yes, iS Clinical is good for acne-prone skin because the brand-focused routine rates Superior for this skin type. Lovi rates Cleansing Complex and Active Serum High for acne-prone skin, helping keep pores clear.

Is iS Clinical good for skin with dark spots?

Yes, iS Clinical offers several products that help with dark spots, such as Cleansing Complex, Active Serum, Hydra-Cool Serum, and Super Serum Advance+, which Lovi rates High for skin with dark spots. Topical antioxidants like vitamin C help brighten skin and fade discoloration.

Journal of Cosmetic Dermatology, 2020Journal of Cosmetic Dermatology, 2020

Is iS Clinical good for mature skin?

Yes, iS Clinical is good for mature skin. Lovi rates Youth Eye Complex Superior and Super Serum Advance+ High for mature skin, while reviewers often mention its anti-aging serums.

Journal of Cosmetic Dermatology, 2020Dermatologic Therapy, 2022

Research behind iS Clinical's key ingredients

Behind these ratings

Lovi rates every product from its full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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