Good Molecules vs ISDIN
Good Molecules and ISDIN are two distinct skincare brands offering thoughtful preparations for daily health and comfort. The American brand, founded in 2019, is known for targeted serums, moisturizers, eye products, and exfoliants utilizing hard-working ingredients like glycerin and hyaluronic acid, while the Spanish brand, established in 1975, is celebrated for sophisticated moisturizers, advanced sunscreens, targeted serums, and soothing eye products driven by meticulously crafted formulas. Good Molecules suits dry skin and skin with dark spots best, whereas the latter suits sensitive skin and dry skin best with gentle and nourishing care. They differ primarily in their origin, founding eras, and the specific active components that deliver meaningful results for various complexions.
Good Molecules is an American skincare brand founded in 2019 and owned by Beautylish, Inc..
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ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
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This page compares some of the most popular Good Molecules and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Good Molecules vs ISDIN products
People Say
Lightweight and non-greasy texture Often MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “absorbs quickly... zero irritation or tacky feeling — Good Molecules Discoloration Correcting Serum”
Affordable price and great value Mostly MentionedNot noted
- “best value for money — Good Molecules Hyaluronic Acid Serum”
- “great value — Good Molecules Niacinamide Serum”
Gentle formula for sensitive skin Often MentionedOften Mentioned
- “no skin purging — Good Molecules Gentle Retinol Cream”
- “leaves my face feeling clean without the drying — Good Molecules Hydrating Facial Cleansing Gel”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Improves skin texture and smoothness Often MentionedOften Mentioned
- “skin looks like brand new baby skin — Good Molecules Overnight Exfoliating Treatment”
- “Leaves skin "baby soft," "super smooth," "polished feel" — Good Molecules Pineapple Exfoliating Powder”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
- “I am more on a dehydrated side and this helps me look hydrated and smooth. — ISDIN Flavo-C Serum”
Hydration and plumping Often MentionedOften Mentioned
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
- “Skin feels intensely hydrated — ISDIN Hyaluronic Concentrate”
- “skin appears smooth and supple — Good Molecules Hyaluronic Acid Serum”
Brightens skin and fades dark spots Often MentionedOften Mentioned
- “scar on your chin doesn't look nearly as noticeable — Good Molecules Discoloration Correcting Serum”
- “skin looks more radiant — Good Molecules Niacinamide Brightening Toner”
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
- “skin looks immediately luminous — ISDIN K-Ox Eyes”
Unpleasant scent or fragrance concerns Sometimes NotedOften Mentioned
- “Strong bergamot smell — Good Molecules Super Peptide Serum”
- “weird faint smell — Good Molecules Gentle Retinol Cream”
- “purge happened in problem areas — Good Molecules Overnight Exfoliating Treatment”
- “smell is overpowering — ISDIN Eryfotona Actinica”
High price point Not notedOften Mentioned
- “very expensive — ISDIN Eryfotona Actinica”
Good Molecules vs ISDIN routines for dry skin
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Cleanser
CeraVe Hydrating Facial Cleanser
Morning · Evening · Once a week
£8.29
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Hydrating Toner
Dear, Klairs Supple Preparation Unscented Toner
Morning
£11.49
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Moisturizer
SKIN1004 Madagascar Centella Probio-Cica Enrich Cream
Morning · Evening · Once a week
£14.74
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SPF
Fusion Water
Morning
£23.49
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
£13.58
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Serum or Treatment
Flavo-C Serum
Evening · Once a week
£38.90
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Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
£17.00
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Cleanser
Hydrating Facial Cleansing Gel
Morning · Evening · Once a week
£10.00
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Hydrating Toner
Dear, Klairs Supple Preparation Unscented Toner
Morning
£11.49
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Moisturizer
Lightweight Daily Moisturizer
Morning · Evening · Once a week
£10.00
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SPF
Sheer Mineral Sunscreen SPF 30
Morning
£24.99
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
£13.58
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Serum or Treatment
Daily Brightening Serum
Evening · Once a week
£6.00
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Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
£17.00
Buy ISDIN routine · £127.49 · 94% fit
Buy Good Molecules routine · £93.06 · 92% fitSee multi-brand routine · 99% fit
Good Molecules vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
£8.29
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
£13.98
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
£14.80
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SPF
Eryfotona Actinica
Morning
£29.20
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Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
£17.00
-
Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
£29.00
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Serum or Treatment
Flavo-C Serum
Evening · Once a week
£38.90
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Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
£19.00
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Cleansing Mask
Dr. Sebagh Deep Exfoliating Mask
Once a week
£61.99
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Cleanser
Hydrating Facial Cleansing Gel
Morning · Evening · Once a week
£10.00
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
£13.98
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Moisturizer
Hyaluronic Acid Serum
Morning · Evening · Once a week
£6.00
-
SPF
Sheer Mineral Sunscreen SPF 30
Morning
£24.99
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
£17.00
-
Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
£29.00
-
Serum or Treatment
Overnight Exfoliating Treatment
Evening · Once a week
£9.00
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Enzyme Powder
Pineapple Exfoliating Powder
Once a week
£16.00
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Cleansing Mask
Dr. Sebagh Deep Exfoliating Mask
Once a week
£61.99
Buy ISDIN routine · £232.16 · 93% fit
Buy Good Molecules routine · £187.96 · 89% fitSee multi-brand routine · 97% fit
Good Molecules vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
£14.99
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
£30.37
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Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
£14.80
-
SPF
Eryfotona Actinica
Morning
£29.20
-
Pre-Cleanser
Pyunkang Yul Deep Cleansing Oil
Evening · Once a week
£23.92
-
Cleansing Toner
REN Clean Skincare Ready Steady Glow Daily AHA Tonic
Evening
£30.99
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Serum or Treatment
Flavo-C Serum
Evening · Once a week
£38.90
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
£19.00
-
Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
£19.00
-
Cleanser
Hydrating Facial Cleansing Gel
Morning · Evening · Once a week
£10.00
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
£30.37
-
Moisturizer
Hyaluronic Acid Serum
Morning · Evening · Once a week
£6.00
-
SPF
Sheer Mineral Sunscreen SPF 30
Morning
£24.99
-
Pre-Cleanser
Pyunkang Yul Deep Cleansing Oil
Evening · Once a week
£23.92
-
Cleansing Toner
REN Clean Skincare Ready Steady Glow Daily AHA Tonic
Evening
£30.99
-
Serum or Treatment
Overnight Exfoliating Treatment
Evening · Once a week
£9.00
-
Enzyme Powder
Pineapple Exfoliating Powder
Once a week
£16.00
-
Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
£19.00
Buy ISDIN routine · £221.17 · 93% fit
Buy Good Molecules routine · £170.27 · 89% fitSee multi-brand routine · 96% fit
Questions and answers
Good Molecules or ISDIN: which is better?
Both brands offer a strong fit for sensitive skin, but ISDIN has a Superior routine fit for oily, combination, and mature skin compared to Good Molecules. Reviewers note that ISDIN provides a lightweight and non-greasy texture, while Good Molecules is often praised for its affordable price and great value.
What is the difference between Good Molecules and ISDIN?
Good Molecules focuses on budget-friendly skincare with no fragrance across the products on this page, whereas ISDIN offers higher-priced, ultralight sunscreens and moisturizers while some of its items may contain fragrance.
Good Molecules or ISDIN for dry skin?
Both Good Molecules and ISDIN offer a Superior Lovi fit for dry skin through their brand routines. Good Molecules features affordable hydration with key ingredients like hyaluronic acid, while ISDIN provides ultralight sunscreens and moisturizers that help lock in moisture.
Good Molecules or ISDIN: which moisturizer is better?
Good Molecules and ISDIN both offer moisturizers that help hydrate the skin, but Good Molecules is often preferred for offering affordable and great value moisturizers. Hyaluronic acid helps improve skin hydration and reduce signs of aging.
Which is more affordable, Good Molecules or ISDIN?
Good Molecules is more affordable, as reviewers often mention its budget-friendly prices and great value, whereas ISDIN is frequently noted for having a high price point.
Which brand offers better options for dry sensitive skin, Good Molecules or ISDIN?
For dry sensitive skin, Good Molecules has a routine fit level of High, while ISDIN offers a Superior fit. Reviewers often mention that ISDIN provides lightweight and non-greasy textures.
How do the founding years and countries of origin compare between Good Molecules and ISDIN?
Good Molecules was founded in 2019 in the United States, whereas ISDIN was founded much earlier in 1975 in Spain.
Do both Good Molecules and ISDIN products contain fragrance in their ingredients?
Every product on the Good Molecules page lists no fragrance in its ingredients. In contrast, ISDIN has fragrance in some of its products on this page, while 3 of 8 products list no fragrance.
Good Molecules or ISDIN for oily skin?
ISDIN is a better fit for oily skin, offering a Superior routine level compared to Good Molecules at High. Reviewers note that ISDIN does better with lightweight and non-greasy textures.
Good Molecules or ISDIN: which sunscreen is better?
Both Good Molecules and ISDIN offer great sunscreen options with high Lovi fit levels for sun protection, but ISDIN stands out for its ultralight texture.
Good Molecules or ISDIN for sensitive skin?
Both Good Molecules and ISDIN achieve a Superior Lovi fit level for sensitive skin. Good Molecules offers budget-friendly products with no fragrance listed on this page, while ISDIN is well-liked for its ultralight sunscreens.
Good Molecules or ISDIN for acne-prone skin?
Both brands offer an equal routine fit level of Superior for acne-prone skin. Good Molecules stands out for its budget-friendly options, while ISDIN is well-liked for its ultralight sunscreens.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
Preparation and evaluation of anti-wrinkle cream containing saffron extract and avocado oil
Chemical peels for acne vulgaris: a systematic review of randomised controlled trials
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Hippophae rhamnoides oil-in-water (O/W) emulsion improves barrier function in healthy human subjects
Development and efficacy assessments of tea seed oil makeup remover
Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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