Good Molecules vs ISDIN
Good Molecules and ISDIN are skincare brands that offer targeted serums, moisturizers, eye products, and exfoliants built on thoughtful formulas. The American brand is celebrated for hardworking ingredients like glycerin and hyaluronic acid, suiting dry skin and mature skin best. Meanwhile, the Spanish brand provides elegant daily comfort and dependable protection that suit dry skin and sensitive skin best. While both cater to overlapping needs, they differ through their distinct heritage, foundational ingredients, and specialized solutions for concerns like acne, dark spots, and aging.
Good Molecules is an American skincare brand founded in 2019 and owned by Beautylish, Inc..
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ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
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This page compares some of the most popular Good Molecules and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Good Molecules vs ISDIN products
People Say
Lightweight and non-greasy texture Often MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “absorbs quickly... zero irritation or tacky feeling — Good Molecules Discoloration Correcting Serum”
Affordable price and great value Mostly MentionedNot noted
- “best value for money — Good Molecules Hyaluronic Acid Serum”
- “great value — Good Molecules Niacinamide Serum”
Gentle formula for sensitive skin Often MentionedOften Mentioned
- “no skin purging — Good Molecules Gentle Retinol Cream”
- “leaves my face feeling clean without the drying — Good Molecules Hydrating Facial Cleansing Gel”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Improves skin texture and smoothness Often MentionedOften Mentioned
- “skin looks like brand new baby skin — Good Molecules Overnight Exfoliating Treatment”
- “Leaves skin "baby soft," "super smooth," "polished feel" — Good Molecules Pineapple Exfoliating Powder”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
- “I am more on a dehydrated side and this helps me look hydrated and smooth. — ISDIN Flavo-C Serum”
Hydration and plumping Often MentionedOften Mentioned
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
- “Skin feels intensely hydrated — ISDIN Hyaluronic Concentrate”
- “skin appears smooth and supple — Good Molecules Hyaluronic Acid Serum”
Brightens skin and fades dark spots Often MentionedOften Mentioned
- “scar on your chin doesn't look nearly as noticeable — Good Molecules Discoloration Correcting Serum”
- “skin looks more radiant — Good Molecules Niacinamide Brightening Toner”
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
- “skin looks immediately luminous — ISDIN K-Ox Eyes”
Unpleasant scent or fragrance concerns Sometimes NotedOften Mentioned
- “Strong bergamot smell — Good Molecules Super Peptide Serum”
- “weird faint smell — Good Molecules Gentle Retinol Cream”
- “purge happened in problem areas — Good Molecules Overnight Exfoliating Treatment”
- “smell is overpowering — ISDIN Eryfotona Actinica”
High price point Not notedOften Mentioned
- “very expensive — ISDIN Eryfotona Actinica”
Good Molecules vs ISDIN routines for dry skin
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Cleanser
CeraVe Hydrating Facial Cleanser
Morning · Evening · Once a week
€9.19
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Hydrating Toner
Pyunkang Yul Calming Deep Moisture Toner
Morning
€15.16
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Moisturizer
Elizabeth Arden Advanced Ceramide Lift and Firm Night Cream
Morning · Evening · Once a week
€53.50
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SPF
Fusion Water
Morning
€23.99
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€15.90
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€48.88
-
Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
€31.93
-
Cleanser
Hydrating Facial Cleansing Gel
Morning · Evening · Once a week
€37.21
-
Hydrating Toner
Pyunkang Yul Calming Deep Moisture Toner
Morning
€15.16
-
Moisturizer
Lightweight Daily Moisturizer
Morning · Evening · Once a week
€26.99
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SPF
Sheer Mineral Sunscreen SPF 30
Morning
€40.89
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€15.90
-
Serum or Treatment
Daily Brightening Serum
Evening · Once a week
€51.74
-
Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
€31.93
Good Molecules vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
€24.75
-
Hydrating Toner
La Mer The Tonic
Morning · Once a week
€103.91
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
€18.47
-
SPF
Eryfotona Actinica
Morning
€75.20
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€40.00
-
Cleansing Toner
Pixi Glow Tonic
Evening
€19.50
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€48.88
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€49.00
-
Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
€19.79
-
Cleanser
Hydrating Facial Cleansing Gel
Morning · Evening · Once a week
€37.21
-
Hydrating Toner
La Mer The Tonic
Morning · Once a week
€103.91
-
Moisturizer
Hyaluronic Acid Serum
Morning · Evening · Once a week
€20.99
-
SPF
Sheer Mineral Sunscreen SPF 30
Morning
€40.89
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€40.00
-
Cleansing Toner
Pixi Glow Tonic
Evening
€19.50
-
Serum or Treatment
Overnight Exfoliating Treatment
Evening · Once a week
€22.99
-
Enzyme Powder
Pineapple Exfoliating Powder
Once a week
€54.73
-
Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
€19.79
Good Molecules vs ISDIN routines for combination skin
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Cleanser
Dr. Althea Amino Acid Gentle Bubble Cleanser
Morning · Evening · Once a week
€13.50
-
Hydrating Toner
La Mer The Tonic
Morning · Once a week
€103.91
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
€18.47
-
SPF
Eryfotona Actinica
Morning
€75.20
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€40.00
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
€17.15
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€48.88
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€49.00
-
Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
€19.79
-
Cleanser
Hydrating Facial Cleansing Gel
Morning · Evening · Once a week
€37.21
-
Hydrating Toner
La Mer The Tonic
Morning · Once a week
€103.91
-
Moisturizer
Hyaluronic Acid Serum
Morning · Evening · Once a week
€20.99
-
SPF
Sheer Mineral Sunscreen SPF 30
Morning
€40.89
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€40.00
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
€17.15
-
Serum or Treatment
Overnight Exfoliating Treatment
Evening · Once a week
€22.99
-
Enzyme Powder
Pineapple Exfoliating Powder
Once a week
€54.73
-
Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
€19.79
Questions and answers
Good Molecules or ISDIN: which is better?
Good Molecules offers better affordability and great value, whereas ISDIN stands out for its ultralight sunscreens and lightweight moisturizers. Both brands help improve skin texture and brighten skin with ingredients like niacinamide and hyaluronic acid.
The British Journal of Dermatology, 2002Dermatologic Therapy, 2022
What is the difference between Good Molecules and ISDIN?
Good Molecules and ISDIN both offer effective options, but Good Molecules is known for affordability while ISDIN is recognized for its ultralight sunscreens and hydration. Good Molecules lists no fragrance across the products on this page, whereas several ISDIN products include fragrance. Both brands achieve superior routine fit levels for dry and mature skin types.
Good Molecules or ISDIN for dry skin?
Both Good Molecules and ISDIN offer a Superior Lovi fit for dry skin through their targeted routines. Shoppers often note that Good Molecules provides affordable and great value moisturizers, while ISDIN is known for its lightweight moisturizers and sunscreens.
Good Molecules or ISDIN: which moisturizer is better?
Good Molecules offers better value with its affordable moisturizers, whereas ISDIN is known for its lightweight formulas. Both brands provide good options, but Good Molecules is generally favored for budget-friendly hydration.
Which is more affordable, Good Molecules or ISDIN?
Good Molecules is more affordable, as reviewers frequently highlight its affordable price and great value, whereas ISDIN is often noted for having a high price point.
Good Molecules or ISDIN for oily skin?
For oily skin, ISDIN reaches a Superior routine fit while Good Molecules reaches a High level. ISDIN is often noted by reviewers for its ultralight and lightweight textures that suit oilier skin types well.
Good Molecules or ISDIN: which sunscreen is better?
Both Good Molecules and ISDIN offer sunscreens on this page with High to Superior Lovi fit levels across skin types. ISDIN is especially praised for its ultralight, makeup-friendly sunscreens, while Good Molecules provides fragrance-free options.
Good Molecules or ISDIN for sensitive skin?
For sensitive skin, both brands offer good options, though Lovi rates ISDIN as Superior and Good Molecules as High. Good Molecules stands out for being fragrance-free across all products on this page, while ISDIN reviewers sometimes note a strong fragrance.
Good Molecules or ISDIN for acne-prone skin?
For acne-prone skin, Lovi rates Good Molecules as High and ISDIN as Superior. Good Molecules features affordable, gentle serums with no added fragrance across the products on this page, while reviewers highlight ISDIN for its ultralight sunscreens.
Good Molecules or ISDIN for combination skin?
For combination skin, Lovi rates ISDIN as Superior while Good Molecules is High. ISDIN stands out for its ultralight sunscreens and lightweight moisturizers, whereas Good Molecules is known for being affordable and great value.
Good Molecules or ISDIN for mature skin?
Both Good Molecules and ISDIN offer a Superior fit for mature skin on their respective pages. Good Molecules is known for affordable values and fragrance-free options, whereas ISDIN is often chosen for ultralight textures and hydration benefits.
Good Molecules or ISDIN for skin with dark spots?
For skin with dark spots, ISDIN has a Superior Lovi fit level across the products on this page, while Good Molecules has a High fit level. Reviewers mention that both brands help brighten skin and fade dark spots.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
Preparation and evaluation of anti-wrinkle cream containing saffron extract and avocado oil
Chemical peels for acne vulgaris: a systematic review of randomised controlled trials
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Hippophae rhamnoides oil-in-water (O/W) emulsion improves barrier function in healthy human subjects
Development and efficacy assessments of tea seed oil makeup remover
Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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