Good Molecules vs ISDIN
Good Molecules and ISDIN are established skincare brands from the United States and Spain, respectively. The American brand is widely loved for its thoughtful range of serums, moisturizers, eye products, and exfoliants featuring glycerin and hyaluronic acid, while the Spanish brand is known for its elegant moisturizers, advanced sunscreens, restorative serums, and targeted eye products. Both suit dry skin and sensitive skin best, but they differ in their specific offerings and origins, with the American brand offering standout options like the Overnight Exfoliating Treatment, Sheer Mineral Sunscreen SPF 30, and Yerba Mate Wake Up Eye Gel, and the European brand providing solutions such as Fusion Water, Eryfotona Actinica, and K-Ox Eyes.
Good Molecules is an American skincare brand founded in 2019 and owned by Beautylish, Inc..
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ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
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This page compares some of the most popular Good Molecules and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Good Molecules vs ISDIN products
People Say
Lightweight and non-greasy texture Often MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “absorbs quickly... zero irritation or tacky feeling — Good Molecules Discoloration Correcting Serum”
Affordable price and great value Mostly MentionedNot noted
- “best value for money — Good Molecules Hyaluronic Acid Serum”
- “only $8 — Good Molecules Gentle Retinol Cream”
- “great value — Good Molecules Niacinamide Serum”
Gentle formula for sensitive skin Often MentionedOften Mentioned
- “no skin purging — Good Molecules Gentle Retinol Cream”
- “leaves my face feeling clean without the drying — Good Molecules Hydrating Facial Cleansing Gel”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Improves skin texture and smoothness Often MentionedOften Mentioned
- “skin looks like brand new baby skin — Good Molecules Overnight Exfoliating Treatment”
- “Leaves skin "baby soft," "super smooth," "polished feel" — Good Molecules Pineapple Exfoliating Powder”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
- “I am more on a dehydrated side and this helps me look hydrated and smooth. — ISDIN Flavo-C Serum”
Hydration and plumping Often MentionedOften Mentioned
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
- “Skin feels intensely hydrated — ISDIN Hyaluronic Concentrate”
- “skin appears smooth and supple — Good Molecules Hyaluronic Acid Serum”
Brightens skin and fades dark spots Often MentionedOften Mentioned
- “scar on your chin doesn't look nearly as noticeable — Good Molecules Discoloration Correcting Serum”
- “skin looks more radiant — Good Molecules Niacinamide Brightening Toner”
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
- “skin looks immediately luminous — ISDIN K-Ox Eyes”
Unpleasant scent or fragrance concerns Sometimes NotedOften Mentioned
- “Strong bergamot smell — Good Molecules Super Peptide Serum”
- “weird faint smell — Good Molecules Gentle Retinol Cream”
- “purge happened in problem areas — Good Molecules Overnight Exfoliating Treatment”
- “smell is overpowering — ISDIN Eryfotona Actinica”
High price point Not notedOften Mentioned
- “very expensive — ISDIN Eryfotona Actinica”
Good Molecules vs ISDIN routines for dry skin
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Cleanser
La Roche-Posay Toleriane Hydrating Gentle Cleanser
Morning · Evening · Once a week
$19.99
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Hydrating Toner
Pyunkang Yul Calming Deep Moisture Toner
Morning
$16.99
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Moisturizer
Lightweight Daily Moisturizer
Morning · Evening · Once a week
$11.97
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SPF
Sheer Mineral Sunscreen SPF 30
Morning
$11.99
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
$21.70
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Serum or Treatment
Daily Brightening Serum
Evening · Once a week
$7.97
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Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
$22.00
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Cleanser
La Roche-Posay Toleriane Hydrating Gentle Cleanser
Morning · Evening · Once a week
$19.99
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Hydrating Toner
Pyunkang Yul Calming Deep Moisture Toner
Morning
$16.99
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Moisturizer
SKIN1004 Madagascar Centella Probio-Cica Enrich Cream
Morning · Evening · Once a week
$22.00
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SPF
Fusion Water
Morning
$38.00
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
$21.70
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Serum or Treatment
Flavo-C Serum
Evening · Once a week
$115.00
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Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
$22.00
Buy Good Molecules routine · $112.61 · 95% fit
Buy ISDIN routine · $255.68 · 94% fitSee multi-brand routine · 99% fit
Good Molecules vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
$15.97
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
$15.60
-
Moisturizer
Hyaluronic Acid Serum
Morning · Evening · Once a week
$11.97
-
SPF
Sheer Mineral Sunscreen SPF 30
Morning
$11.99
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
$50.00
-
Cleansing Toner
Pixi Glow Tonic
Evening
$28.42
-
Serum or Treatment
Overnight Exfoliating Treatment
Evening · Once a week
$5.99
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Enzyme Powder
Pineapple Exfoliating Powder
Once a week
$16.00
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Cleansing Mask
Revision Skincare Black Mask
Once a week
$79.00
-
Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
$15.97
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
$15.60
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
$18.99
-
SPF
Eryfotona Actinica
Morning
$46.00
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
$50.00
-
Cleansing Toner
Pixi Glow Tonic
Evening
$28.42
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
$115.00
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Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
$69.00
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Cleansing Mask
Revision Skincare Black Mask
Once a week
$79.00
Buy Good Molecules routine · $234.94 · 93% fit
Buy ISDIN routine · $437.98 · 93% fitSee multi-brand routine · 98% fit
Good Molecules vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
$28.08
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
$25.60
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
$18.99
-
SPF
Eryfotona Actinica
Morning
$46.00
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
$50.00
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
$18.90
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Serum or Treatment
Flavo-C Serum
Evening · Once a week
$115.00
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Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
$69.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
$58.00
-
Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
$28.08
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
$25.60
-
Moisturizer
Hyaluronic Acid Serum
Morning · Evening · Once a week
$11.97
-
SPF
Sheer Mineral Sunscreen SPF 30
Morning
$11.99
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
$50.00
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
$18.90
-
Serum or Treatment
Overnight Exfoliating Treatment
Evening · Once a week
$5.99
-
Enzyme Powder
Pineapple Exfoliating Powder
Once a week
$16.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
$58.00
Buy ISDIN routine · $429.57 · 93% fit
Buy Good Molecules routine · $226.53 · 92% fitSee multi-brand routine · 97% fit
Questions and answers
Good Molecules or ISDIN: which is better?
Good Molecules and ISDIN both offer equal routine fit across all skin types, with Good Molecules focusing on affordability and fragrance-free options while ISDIN stands out for its ultralight sunscreens and lightweight moisturizers. Topical hyaluronic acid, featured in both brands, helps improve skin hydration and signs of aging.
What is the difference between Good Molecules and ISDIN?
Good Molecules offers budget-friendly products with no added fragrance across the products on this page, whereas ISDIN is known for ultralight sunscreens and a higher price point. Both brands achieve equal routine fit levels across all skin types.
Good Molecules or ISDIN for dry skin?
Both Good Molecules and ISDIN achieve a Superior Lovi fit level for dry skin. Good Molecules offers budget-friendly hydration, while ISDIN provides ultralight sunscreens and moisturizers.
Good Molecules or ISDIN: which moisturizer is better?
Both brands offer strong options, as Good Molecules provides affordable and hydrating moisturizers while ISDIN is known for lightweight moisturizers, and Lovi rates both as equal for dry skin. Hyaluronic acid helps provide hydration and anti-aging benefits in moisturizers from these brands.
Which is more affordable, Good Molecules or ISDIN?
Good Molecules is more affordable, offering budget-friendly serums and moisturizers compared to the high price point of ISDIN.
Which brand has more products without fragrance, Good Molecules or ISDIN?
Good Molecules has more products without fragrance, as every single product on its page lists no fragrance in its ingredients. In contrast, ISDIN has fragrance listed in 5 of its 8 products on this page.
What are the main founding details and parent companies of Good Molecules and ISDIN?
Good Molecules was founded in 2019 in the United States and is owned by Beautylish, Inc., whereas ISDIN was founded in 1975 in Spain and is owned by Puig.
How do Good Molecules and ISDIN compare regarding lightweight and non-greasy textures according to reviewers?
Reviewers note that ISDIN does better regarding lightweight and non-greasy texture compared to Good Molecules.
Good Molecules or ISDIN for oily skin?
Both Good Molecules and ISDIN achieve a Superior routine fit level for oily skin. Good Molecules offers budget-friendly serums and lightweight moisturizers, while ISDIN is widely praised for its ultralight and makeup-friendly sunscreens.
Good Molecules or ISDIN: which sunscreen is better?
Both Good Molecules and ISDIN offer great sunscreen options on this page, with Good Molecules Sheer Mineral Sunscreen SPF 30 and ISDIN Eryfotona Actinica both achieving a Superior Lovi fit level for mature, sensitive, and dry sensitive skin. ISDIN sunscreens are mostly mentioned by reviewers for their ultralight and makeup-friendly textures, while Good Molecules is known for being affordable. Topical antioxidants and sunscreens may help protect against UV-induced skin damage.
Good Molecules or ISDIN for sensitive skin?
Both Good Molecules and ISDIN are suitable choices for sensitive skin, as Lovi rates both brands as having a Superior routine fit for this skin type. Good Molecules features fragrance-free products on this page, while ISDIN is recognized for its ultralight and skin-friendly sunscreens.
Good Molecules or ISDIN for acne-prone skin?
Both Good Molecules and ISDIN are suitable choices for acne-prone skin, as Lovi rates their routines as Superior. Good Molecules is known for its budget-friendly options, while ISDIN offers ultralight sunscreens and specialized formulas that help manage blemishes.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
Preparation and evaluation of anti-wrinkle cream containing saffron extract and avocado oil
Chemical peels for acne vulgaris: a systematic review of randomised controlled trials
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Hippophae rhamnoides oil-in-water (O/W) emulsion improves barrier function in healthy human subjects
Development and efficacy assessments of tea seed oil makeup remover
Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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