Good Molecules vs ISDIN
Good Molecules and ISDIN are skincare brands, founded in America and Spain respectively, that offer thoughtfully formulated serums, moisturizers, sunscreens, and eye products. The American brand features key ingredients like glycerin, which improves skin hydration and restores barrier function, and hyaluronic acid, which lengthens the effect of wrinkle-reducing toxins. While the former brand suits sensitive skin and acne-prone skin best, the latter brand suits acne-prone skin and combination skin best. They differ in their origins and specific compositions, yet both deliver gentle efficacy through daily use.
Good Molecules is an American skincare brand founded in 2019 and owned by Beautylish, Inc..
beautymatter.comgoodmolecules.compitchbook.compreqin.com
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
puig.combeautymatter.comuploads.puig.com
This page compares some of the most popular Good Molecules and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Good Molecules vs ISDIN products
People Say
Lightweight and non-greasy texture Often MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “absorbs quickly... zero irritation or tacky feeling — Good Molecules Discoloration Correcting Serum”
Affordable price and great value Mostly MentionedNot noted
- “best value for money — Good Molecules Hyaluronic Acid Serum”
- “great value — Good Molecules Niacinamide Serum”
Gentle formula for sensitive skin Often MentionedOften Mentioned
- “no skin purging — Good Molecules Gentle Retinol Cream”
- “leaves my face feeling clean without the drying — Good Molecules Hydrating Facial Cleansing Gel”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Improves skin texture and smoothness Often MentionedOften Mentioned
- “skin looks like brand new baby skin — Good Molecules Overnight Exfoliating Treatment”
- “Leaves skin "baby soft," "super smooth," "polished feel" — Good Molecules Pineapple Exfoliating Powder”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
- “I am more on a dehydrated side and this helps me look hydrated and smooth. — ISDIN Flavo-C Serum”
Hydration and plumping Often MentionedOften Mentioned
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
- “Skin feels intensely hydrated — ISDIN Hyaluronic Concentrate”
- “skin appears smooth and supple — Good Molecules Hyaluronic Acid Serum”
Brightens skin and fades dark spots Often MentionedOften Mentioned
- “scar on your chin doesn't look nearly as noticeable — Good Molecules Discoloration Correcting Serum”
- “skin looks more radiant — Good Molecules Niacinamide Brightening Toner”
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
- “skin looks immediately luminous — ISDIN K-Ox Eyes”
Unpleasant scent or fragrance concerns Sometimes NotedOften Mentioned
- “Strong bergamot smell — Good Molecules Super Peptide Serum”
- “weird faint smell — Good Molecules Gentle Retinol Cream”
- “purge happened in problem areas — Good Molecules Overnight Exfoliating Treatment”
- “smell is overpowering — ISDIN Eryfotona Actinica”
High price point Not notedOften Mentioned
- “very expensive — ISDIN Eryfotona Actinica”
Good Molecules vs ISDIN routines for dry skin
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Cleanser
Hydrating Facial Cleansing Gel
Morning · Evening · Once a week
AED 88.68
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Moisturizer
Lightweight Daily Moisturizer
Morning · Evening · Once a week
AED 70.98
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SPF
Sheer Mineral Sunscreen SPF 30
Morning
AED 69.98
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
AED 35.29
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Cleansing Toner
ROUND LAB 1025 Dokdo Cleansing Water
Evening
AED 38.99
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Serum or Treatment
Daily Brightening Serum
Evening · Once a week
AED 50.96
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Enzyme Powder
Pineapple Exfoliating Powder
Once a week
AED 92.37
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Nourishing Mask
Mediheal Watermide Essential Mask
Once a week
AED 65.00
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Cleanser
CeraVe Hydrating Facial Cleanser
Morning · Evening · Once a week
AED 32.95
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Moisturizer
SKIN1004 Madagascar Centella Probio-Cica Enrich Cream
Morning · Evening · Once a week
AED 34.80
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SPF
Fusion Water
Morning
AED 91.99
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
AED 35.29
-
Cleansing Toner
ROUND LAB 1025 Dokdo Cleansing Water
Evening
AED 38.99
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Serum or Treatment
Retinal Intense Serum
Evening · Once a week
AED 392.99
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Enzyme Powder
VT Cica Mild Powder Wash
Once a week
AED 47.62
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Nourishing Mask
Mediheal Watermide Essential Mask
Once a week
AED 65.00
Buy Good Molecules routine · AED 512.25 · 89% fit
Buy ISDIN routine · AED 739.63 · 88% fitSee multi-brand routine · 96% fit
Good Molecules vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
AED 49.95
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
AED 49.99
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
AED 33.40
-
SPF
Fusion Water
Morning
AED 91.99
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
AED 179.45
-
Cleansing Toner
Pixi Glow Tonic
Evening
AED 120.00
-
Serum or Treatment
Retinal Intense Serum
Evening · Once a week
AED 392.99
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
AED 101.09
-
Cleansing Mask
Revision Skincare Black Mask
Once a week
AED 204.00
-
Cleanser
Hydrating Facial Cleansing Gel
Morning · Evening · Once a week
AED 88.68
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
AED 49.99
-
Moisturizer
Hyaluronic Acid Serum
Morning · Evening · Once a week
AED 38.61
-
SPF
Sheer Mineral Sunscreen SPF 30
Morning
AED 69.98
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
AED 179.45
-
Cleansing Toner
Pixi Glow Tonic
Evening
AED 120.00
-
Serum or Treatment
Overnight Exfoliating Treatment
Evening · Once a week
AED 44.50
-
Enzyme Powder
Pineapple Exfoliating Powder
Once a week
AED 92.37
-
Cleansing Mask
Revision Skincare Black Mask
Once a week
AED 204.00
Buy ISDIN routine · AED 1,222.86 · 91% fit
Buy Good Molecules routine · AED 887.58 · 89% fitSee multi-brand routine · 97% fit
Good Molecules vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
AED 84.53
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
AED 145.00
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
AED 33.40
-
SPF
Fusion Water
Morning
AED 91.99
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
AED 179.45
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
AED 53.12
-
Serum or Treatment
Retinal Intense Serum
Evening · Once a week
AED 392.99
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
AED 101.09
-
Cleansing Mask
KORA Organics Turmeric Brightening & Exfoliating Mask
Once a week
AED 122.93
-
Cleanser
Hydrating Facial Cleansing Gel
Morning · Evening · Once a week
AED 88.68
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
AED 145.00
-
Moisturizer
Hyaluronic Acid Serum
Morning · Evening · Once a week
AED 38.61
-
SPF
Sheer Mineral Sunscreen SPF 30
Morning
AED 69.98
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
AED 179.45
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
AED 53.12
-
Serum or Treatment
Overnight Exfoliating Treatment
Evening · Once a week
AED 44.50
-
Enzyme Powder
Pineapple Exfoliating Powder
Once a week
AED 92.37
-
Cleansing Mask
KORA Organics Turmeric Brightening & Exfoliating Mask
Once a week
AED 122.93
Buy ISDIN routine · AED 1,204.50 · 92% fit
Buy Good Molecules routine · AED 834.64 · 89% fitSee multi-brand routine · 96% fit
Questions and answers
Good Molecules or ISDIN: which is better?
Good Molecules offers better affordability and value, whereas ISDIN is often noted for ultralight sunscreens and lightweight moisturizers. Both brands fit sensitive skin, acne-prone skin, and skin with dark spots well, while every product on the Good Molecules page lists no fragrance in its ingredients.
What is the difference between Good Molecules and ISDIN?
Good Molecules offers affordable and budget-friendly products with fragrance-free formulas, whereas ISDIN is known for its higher-priced, ultralight sunscreens and moisturizers that may contain fragrance. Both brands perform similarly for sensitive and acne-prone skin, but ISDIN achieves a superior Lovi fit level for mature, oily, and combination skin.
Good Molecules or ISDIN for dry skin?
Good Molecules and ISDIN both offer a High routine fit for dry skin. Good Molecules stands out for being very budget-friendly, while ISDIN is known for ultralight sunscreens.
Good Molecules or ISDIN: which moisturizer is better?
Both brands offer popular moisturizers, but Good Molecules is noted for being affordable and great value, whereas ISDIN is recognized for its lightweight formulas.
Which is more affordable, Good Molecules or ISDIN?
Good Molecules is more affordable, as reviewers highlight its affordable price and great value, whereas a high price point is a common concern for ISDIN.
Which brand has more fragrance-free products, Good Molecules or ISDIN?
Good Molecules has more fragrance-free products, as every product on its page lists no fragrance in its ingredients, while ISDIN only has 3 out of 8 products without fragrance.
How do Good Molecules and ISDIN compare for mature skin routines?
For mature skin routines, Lovi rates Good Molecules High and ISDIN Superior. Reviewers note that Good Molecules offers affordable and great value serums, while ISDIN is known for its lightweight moisturizers.
What are the main company origins and ownership differences between Good Molecules and ISDIN?
Good Molecules was founded in the United States in 2019 and is owned by Beautylish, Inc., whereas ISDIN was founded in Spain in 1975 and is owned by Puig.
Good Molecules or ISDIN for oily skin?
For oily skin, ISDIN reaches a Superior routine fit level while Good Molecules reaches a High level. Reviewers on this page mention that ISDIN offers ultralight sunscreens and lightweight moisturizers, which helps manage oily skin.
Good Molecules or ISDIN: which sunscreen is better?
Both Good Molecules and ISDIN offer sunscreens with top ratings on this page, as Good Molecules Sheer Mineral Sunscreen SPF 30 and ISDIN Eryfotona Actinica and Fusion Water all reach a Superior Lovi fit level for dry and sensitive skin. ISDIN sunscreens are frequently noted by reviewers for their ultralight and makeup-friendly feel, whereas Good Molecules provides an affordable, fragrance-free option.
Good Molecules or ISDIN for sensitive skin?
Both Good Molecules and ISDIN are great options, as Lovi rates both brands as Superior for sensitive skin. Reviewers note that both brands offer a gentle formula for sensitive skin.
Good Molecules or ISDIN for acne-prone skin?
Both Good Molecules and ISDIN are great options for acne-prone skin, as Lovi rates both brands as Superior for this skin type. Good Molecules features affordable options with no added fragrance across the products on this page, while ISDIN is well-liked for its ultralight sunscreens.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
Preparation and evaluation of anti-wrinkle cream containing saffron extract and avocado oil
Chemical peels for acne vulgaris: a systematic review of randomised controlled trials
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Hippophae rhamnoides oil-in-water (O/W) emulsion improves barrier function in healthy human subjects
Development and efficacy assessments of tea seed oil makeup remover
Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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