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Good Molecules vs ISDIN

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Good Molecules and ISDIN are two distinct skincare lines known for thoughtful daily care, offering serums, moisturizers, eye products, exfoliants, and sunscreens that suit dry, sensitive, and acne-prone skin. The American brand Good Molecules, founded in 2019 and owned by Beautylish, Inc., is widely loved for formulations featuring glycerin and hyaluronic acid, while the Spanish brand ISDIN, founded in 1975 and owned by Puig, crafts advanced creations that respect delicate moisture barriers. Both brands differ in their specific targeted solutions, with the former delivering hydration and barrier restoration through its core components, and the latter helping to maintain a healthy, balanced, and protected complexion through consistent use.

Good Molecules is an American skincare brand founded in 2019 and owned by Beautylish, Inc..

beautymatter.comgoodmolecules.compitchbook.compreqin.com

ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

puig.combeautymatter.comuploads.puig.com

This page compares some of the most popular Good Molecules and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Good Molecules vs ISDIN products

People Say

Good MoleculesISDIN
  • Lightweight and non-greasy texture Often MentionedMostly Mentioned
    • “absorbs instantly — ISDIN Eryfotona Actinica”
    • “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
    • “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
    • “absorbs quickly... zero irritation or tacky feeling — Good Molecules Discoloration Correcting Serum”
  • Affordable price and great value Mostly MentionedNot noted
    • “best value for money — Good Molecules Hyaluronic Acid Serum”
    • “great value — Good Molecules Niacinamide Serum”
  • Gentle formula for sensitive skin Often MentionedOften Mentioned
    • “no skin purging — Good Molecules Gentle Retinol Cream”
    • “leaves my face feeling clean without the drying — Good Molecules Hydrating Facial Cleansing Gel”
    • “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
    • “no excessive exfoliation — ISDIN Retinal Intense Serum”
  • Improves skin texture and smoothness Often MentionedOften Mentioned
    • “skin looks like brand new baby skin — Good Molecules Overnight Exfoliating Treatment”
    • “Leaves skin "baby soft," "super smooth," "polished feel" — Good Molecules Pineapple Exfoliating Powder”
    • “skin looks smooth and healthy — ISDIN K-Ox Eyes”
    • “I am more on a dehydrated side and this helps me look hydrated and smooth. — ISDIN Flavo-C Serum”
  • Hydration and plumping Often MentionedOften Mentioned
    • “Improved moisture and texture — ISDIN Hyaluronic Moisture”
    • “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
    • “Skin feels intensely hydrated — ISDIN Hyaluronic Concentrate”
    • “skin appears smooth and supple — Good Molecules Hyaluronic Acid Serum”
  • Brightens skin and fades dark spots Often MentionedOften Mentioned
    • “scar on your chin doesn't look nearly as noticeable — Good Molecules Discoloration Correcting Serum”
    • “skin looks more radiant — Good Molecules Niacinamide Brightening Toner”
    • “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
    • “skin looks immediately luminous — ISDIN K-Ox Eyes”
  • Unpleasant scent or fragrance concerns Sometimes NotedOften Mentioned
    • “Strong bergamot smell — Good Molecules Super Peptide Serum”
    • “weird faint smell — Good Molecules Gentle Retinol Cream”
    • “purge happened in problem areas — Good Molecules Overnight Exfoliating Treatment”
    • “smell is overpowering — ISDIN Eryfotona Actinica”
  • High price point Not notedOften Mentioned
    • “very expensive — ISDIN Eryfotona Actinica”

Good Molecules vs ISDIN routines for dry skin

See multi-brand routine · 98% fit

Good Molecules vs ISDIN routines for oily skin

See multi-brand routine · 97% fit

Good Molecules vs ISDIN routines for combination skin

See multi-brand routine · 96% fit

Questions and answers

Good Molecules or ISDIN: which is better?

Good Molecules and ISDIN both offer effective options, with Good Molecules favored for affordable value and ISDIN for ultralight sunscreens and hydration. Lovi rates the routine fit for dry skin as Superior for both brands. Niacinamide helps reduce cutaneous pigmentation and suppress melanosome transfer.

The British Journal of Dermatology, 2002Antioxidants, 2021

What is the difference between Good Molecules and ISDIN?

Good Molecules offers affordable and budget-friendly products with no fragrance listed across the products on this page, while ISDIN features a higher price point and includes fragrance in some of its formulas. Both brands provide lightweight textures, but ISDIN achieves a Superior routine fit for oily skin and combination skin where Good Molecules reaches a High fit.

Good Molecules or ISDIN for dry skin?

Both Good Molecules and ISDIN achieve a Superior Lovi routine fit level for dry skin. Good Molecules offers budget-friendly products with no fragrance on this page, while ISDIN features ultralight sunscreens and moisturizers.

Good Molecules or ISDIN: which moisturizer is better?

Good Molecules offers better value with affordable and hydrating moisturizers, whereas ISDIN is known for lightweight moisturizers that come at a higher price point. Both brands provide options with glycerin and hyaluronic acid, which helps hydrate the skin.

Dermatologic Therapy, 2022

Which is more affordable, Good Molecules or ISDIN?

Good Molecules is more affordable, as reviewers on this page frequently highlight its affordable price and great value, whereas ISDIN is often noted for its high price point.

Which brand has more products without fragrance, Good Molecules or ISDIN?

Good Molecules has more products without fragrance, as every product on its page lists no fragrance in its ingredients, whereas ISDIN only has 3 of 8 products without fragrance on this page.

Which brand offers a better routine fit for oily acne-prone skin?

ISDIN offers a better routine fit for oily acne-prone skin, achieving a Superior fit level compared to the High fit level of Good Molecules.

Good Molecules or ISDIN for oily skin?

For oily skin, ISDIN has a Superior routine fit, while Good Molecules has a High routine fit on the products on this page.

Good Molecules or ISDIN: which sunscreen is better?

Both Good Molecules and ISDIN offer sunscreens with a Superior fit level for dry sensitive skin, sensitive skin, skin with dark spots, and mature skin on this page. Reviewers frequently note that ISDIN sunscreens are ultralight, lightweight, makeup-friendly, and skin-friendly.

Good Molecules or ISDIN for sensitive skin?

For sensitive skin, both brands offer products on this page with a Lovi fit level of High, while Good Molecules is unlikely to cause fragrance concerns since every product on this page lists no fragrance in its ingredients.

Good Molecules or ISDIN for acne-prone skin?

Both Good Molecules and ISDIN achieve a Superior routine fit for acne-prone skin on the products on this page. Good Molecules stands out for its affordable serums, while ISDIN is noted for its ultralight sunscreens.

Good Molecules or ISDIN for mature skin?

Both Good Molecules and ISDIN have a Superior Lovi fit level for mature skin. Topical hyaluronic acid and retinol help improve signs of skin aging and support collagen accumulation in mature skin.

Dermatologic Therapy, 2022The Journal of Investigative Dermatology, 2000

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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