Good Molecules vs ISDIN
Good Molecules and ISDIN are established skincare brands offering distinct approaches to daily routines, with the former founded in 2019 by Beautylish, Inc. and the latter established in 1975 by Puig. The American brand is widely loved for its thoughtful range of serums, moisturizers, eye products, exfoliants, and more, which are carefully formulated with glycerin and hyaluronic acid to suit dry skin and acne-prone skin best. Meanwhile, skincare enthusiasts love the Spanish brand for its sophisticated moisturizers, advanced sunscreens, targeted serums, and soothing eye products, all driven by meticulously engineered formulas that suit sensitive skin and oily acne-prone skin best. While both brands feature standout options for concerns like dark spots and mature skin, they differ in their foundational compositions and regional heritage.
Good Molecules is an American skincare brand founded in 2019 and owned by Beautylish, Inc..
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ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
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This page compares some of the most popular Good Molecules and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Good Molecules vs ISDIN products
People Say
Lightweight and non-greasy texture Often MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “absorbs quickly... zero irritation or tacky feeling — Good Molecules Discoloration Correcting Serum”
Affordable price and great value Mostly MentionedNot noted
- “best value for money — Good Molecules Hyaluronic Acid Serum”
- “great value — Good Molecules Niacinamide Serum”
Gentle formula for sensitive skin Often MentionedOften Mentioned
- “no skin purging — Good Molecules Gentle Retinol Cream”
- “leaves my face feeling clean without the drying — Good Molecules Hydrating Facial Cleansing Gel”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Improves skin texture and smoothness Often MentionedOften Mentioned
- “skin looks like brand new baby skin — Good Molecules Overnight Exfoliating Treatment”
- “Leaves skin "baby soft," "super smooth," "polished feel" — Good Molecules Pineapple Exfoliating Powder”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
- “I am more on a dehydrated side and this helps me look hydrated and smooth. — ISDIN Flavo-C Serum”
Hydration and plumping Often MentionedOften Mentioned
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
- “Skin feels intensely hydrated — ISDIN Hyaluronic Concentrate”
- “skin appears smooth and supple — Good Molecules Hyaluronic Acid Serum”
Brightens skin and fades dark spots Often MentionedOften Mentioned
- “scar on your chin doesn't look nearly as noticeable — Good Molecules Discoloration Correcting Serum”
- “skin looks more radiant — Good Molecules Niacinamide Brightening Toner”
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
- “skin looks immediately luminous — ISDIN K-Ox Eyes”
Unpleasant scent or fragrance concerns Sometimes NotedOften Mentioned
- “Strong bergamot smell — Good Molecules Super Peptide Serum”
- “weird faint smell — Good Molecules Gentle Retinol Cream”
- “purge happened in problem areas — Good Molecules Overnight Exfoliating Treatment”
- “smell is overpowering — ISDIN Eryfotona Actinica”
High price point Not notedOften Mentioned
- “very expensive — ISDIN Eryfotona Actinica”
Good Molecules vs ISDIN routines for dry skin
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Cleanser
La Roche-Posay Toleriane Hydrating Gentle Cleanser
Morning · Evening · Once a week
A$26.59
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Hydrating Toner
Pyunkang Yul Calming Deep Moisture Toner
Morning
A$23.99
-
Moisturizer
d'Alba First Spray Serum
Morning · Evening · Once a week
A$26.09
-
SPF
Bioderma Photoderm Mineral Fluide SPF50+
Morning
A$24.49
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
A$27.35
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
A$30.99
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
A$35.50
-
Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
A$28.48
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Cleanser
La Roche-Posay Toleriane Hydrating Gentle Cleanser
Morning · Evening · Once a week
A$26.59
-
Hydrating Toner
Pyunkang Yul Calming Deep Moisture Toner
Morning
A$23.99
-
Moisturizer
Hyaluronic Acid Serum
Morning · Evening · Once a week
A$21.06
-
SPF
Bioderma Photoderm Mineral Fluide SPF50+
Morning
A$24.49
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
A$27.35
-
Serum or Treatment
Discoloration Correcting Serum
Evening · Once a week
A$54.00
-
Enzyme Powder
Pineapple Exfoliating Powder
Once a week
A$47.76
-
Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
A$28.48
Buy ISDIN routine · A$223.48 · 94% fit
Buy Good Molecules routine · A$253.72 · 93% fitSee multi-brand routine · 97% fit
Good Molecules vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
A$13.99
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
A$34.66
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
A$22.99
-
SPF
La Roche-Posay Anthelios Clear Skin Dry Touch Sunscreen SPF 60
Morning
A$27.99
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
A$80.43
-
Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
A$75.95
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
A$30.99
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
A$35.50
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
A$118.35
-
Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
A$13.99
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
A$34.66
-
Moisturizer
Hyaluronic Acid Serum
Morning · Evening · Once a week
A$21.06
-
SPF
La Roche-Posay Anthelios Clear Skin Dry Touch Sunscreen SPF 60
Morning
A$27.99
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
A$80.43
-
Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
A$75.95
-
Serum or Treatment
Niacinamide Serum
Evening · Once a week
A$19.90
-
Enzyme Powder
Pineapple Exfoliating Powder
Once a week
A$47.76
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
A$118.35
Buy ISDIN routine · A$440.85 · 94% fit
Buy Good Molecules routine · A$440.09 · 91% fitSee multi-brand routine · 96% fit
Good Molecules vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
A$73.61
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
A$42.00
-
Moisturizer
COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)
Morning · Evening · Once a week
A$22.99
-
Pre-Cleanser
Pyunkang Yul Deep Cleansing Oil
Evening · Once a week
A$30.99
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
A$29.90
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
A$30.99
-
Enzyme Powder
FANCL Facial Washing Powder
Once a week
A$35.50
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
A$118.35
-
Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
A$73.61
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
A$42.00
-
Moisturizer
Hyaluronic Acid Serum
Morning · Evening · Once a week
A$21.06
-
Pre-Cleanser
Pyunkang Yul Deep Cleansing Oil
Evening · Once a week
A$30.99
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
A$29.90
-
Serum or Treatment
Niacinamide Serum
Evening · Once a week
A$19.90
-
Enzyme Powder
Pineapple Exfoliating Powder
Once a week
A$47.76
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
A$118.35
Buy ISDIN routine · A$384.33 · 93% fit
Buy Good Molecules routine · A$383.57 · 89% fitSee multi-brand routine · 95% fit
Questions and answers
Good Molecules or ISDIN: which is better?
Good Molecules is the better choice for shoppers seeking budget-friendly skincare, as reviewers frequently highlight its affordable and great value serums and moisturizers. In contrast, ISDIN tends to be pricier with a high price point, though it stands out for its ultralight and makeup-friendly sunscreens.
What is the difference between Good Molecules and ISDIN?
Good Molecules stands out for budget-friendly serums and moisturizers, whereas ISDIN is known for ultralight, makeup-friendly sunscreens with a higher price point. Both brands offer fragrance-free options across some products on this page, but ISDIN formulas may include fragrance in certain items while Good Molecules lists no fragrance across the products on this page.
Good Molecules or ISDIN for dry skin?
Both Good Molecules and ISDIN achieve a Superior Lovi routine fit for dry skin. Reviewers highlight Good Molecules for offering affordable and hydrating moisturizers, while ISDIN is noted for lightweight moisturizers.
Good Molecules or ISDIN: which moisturizer is better?
Good Molecules offers better moisturizer options for shoppers seeking value, as its products on this page are known for being affordable and hydrating moisturizers, while ISDIN is often noted for a high price point. Lovi rates the routine fit for dry skin as Superior for both brands. Topical hyaluronic acid, a key ingredient across Good Molecules products, helps improve skin quality and signs of skin aging.
Which is more affordable, Good Molecules or ISDIN?
Good Molecules offers more affordable products and better value compared to ISDIN. Reviewers on this page frequently mention the brand's affordability, whereas ISDIN is often noted for its high price point.
Good Molecules or ISDIN for fading dark spots?
Both Good Molecules and ISDIN are great for fading dark spots, as Lovi rates both brands as having a Superior routine fit for skin with dark spots. Reviewers also say that both brands are equally good at brightening skin and fading dark spots. Niacinamide, featured in Good Molecules products, helps suppress melanosome transfer to reduce skin pigmentation.
Which brand has fragrance-free products, Good Molecules or ISDIN?
Good Molecules has fragrance-free products, as every product on its page lists no fragrance in its ingredients, whereas ISDIN has fragrance in 5 of its 8 products on this page.
Good Molecules or ISDIN for oily skin?
Both Good Molecules and ISDIN offer a Superior routine fit for oily skin based on the products on this page. Reviewers note that ISDIN excels with lightweight and non-greasy textures, while Good Molecules is favored for its affordable price and great value.
Good Molecules or ISDIN: which sunscreen is better?
Good Molecules Sheer Mineral Sunscreen SPF 30 achieves a Lovi fit level of Superior for dry sensitive skin, dry skin, sensitive skin, skin with dark spots, and mature skin, while ISDIN Eryfotona Actinica achieves a Lovi fit level of Superior for mature skin, sensitive skin, skin with dark spots, and dry sensitive skin.
Good Molecules or ISDIN for sensitive skin?
Both Good Molecules and ISDIN offer a Superior fit for sensitive skin on the products on this page. Good Molecules stands out for having no fragrance in any of its products, while ISDIN is well-known for its ultralight sunscreens.
Good Molecules or ISDIN for acne-prone skin?
Both Good Molecules and ISDIN achieve a Superior routine fit for acne-prone skin on Lovi. Good Molecules offers budget-friendly serums with key ingredients like niacinamide that help control pigmentation, whereas ISDIN features ultralight, skin-friendly sunscreens.
Good Molecules or ISDIN for combination skin?
ISDIN is a Superior fit for combination skin, whereas Good Molecules has a High fit level for this skin type.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
Preparation and evaluation of anti-wrinkle cream containing saffron extract and avocado oil
Chemical peels for acne vulgaris: a systematic review of randomised controlled trials
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Hippophae rhamnoides oil-in-water (O/W) emulsion improves barrier function in healthy human subjects
Development and efficacy assessments of tea seed oil makeup remover
Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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