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Good Molecules vs ISDIN

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Good Molecules and ISDIN are two distinct skincare brands with different origins and core strengths. The American brand Good Molecules, founded in 2019, is known for its gentle serums, moisturizers, and exfoliants powered by glycerin and hyaluronic acid, making it best suited for dry and sensitive skin. In contrast, the Spanish brand ISDIN, founded in 1975, offers sophisticated sunscreens, moisturizers, and targeted serums that suit dry and combination skin. While both companies address concerns like acne, dark spots, and aging through standout targeted treatments, they differ in their heritage, ingredient focus, and ideal skin types.

Good Molecules is an American skincare brand founded in 2019 and owned by Beautylish, Inc..

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ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

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This page compares some of the most popular Good Molecules and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Good Molecules vs ISDIN products

People Say

Good MoleculesISDIN
  • Lightweight and non-greasy texture Often MentionedMostly Mentioned
    • “absorbs instantly — ISDIN Eryfotona Actinica”
    • “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
    • “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
    • “absorbs quickly... zero irritation or tacky feeling — Good Molecules Discoloration Correcting Serum”
  • Affordable price and great value Mostly MentionedNot noted
    • “best value for money — Good Molecules Hyaluronic Acid Serum”
    • “great value — Good Molecules Niacinamide Serum”
  • Gentle formula for sensitive skin Often MentionedOften Mentioned
    • “no skin purging — Good Molecules Gentle Retinol Cream”
    • “leaves my face feeling clean without the drying — Good Molecules Hydrating Facial Cleansing Gel”
    • “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
    • “no excessive exfoliation — ISDIN Retinal Intense Serum”
  • Improves skin texture and smoothness Often MentionedOften Mentioned
    • “skin looks like brand new baby skin — Good Molecules Overnight Exfoliating Treatment”
    • “Leaves skin "baby soft," "super smooth," "polished feel" — Good Molecules Pineapple Exfoliating Powder”
    • “skin looks smooth and healthy — ISDIN K-Ox Eyes”
    • “I am more on a dehydrated side and this helps me look hydrated and smooth. — ISDIN Flavo-C Serum”
  • Hydration and plumping Often MentionedOften Mentioned
    • “Improved moisture and texture — ISDIN Hyaluronic Moisture”
    • “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
    • “Skin feels intensely hydrated — ISDIN Hyaluronic Concentrate”
    • “skin appears smooth and supple — Good Molecules Hyaluronic Acid Serum”
  • Brightens skin and fades dark spots Often MentionedOften Mentioned
    • “scar on your chin doesn't look nearly as noticeable — Good Molecules Discoloration Correcting Serum”
    • “skin looks more radiant — Good Molecules Niacinamide Brightening Toner”
    • “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
    • “skin looks immediately luminous — ISDIN K-Ox Eyes”
  • Unpleasant scent or fragrance concerns Sometimes NotedOften Mentioned
    • “Strong bergamot smell — Good Molecules Super Peptide Serum”
    • “weird faint smell — Good Molecules Gentle Retinol Cream”
    • “purge happened in problem areas — Good Molecules Overnight Exfoliating Treatment”
    • “smell is overpowering — ISDIN Eryfotona Actinica”
  • High price point Not notedOften Mentioned
    • “very expensive — ISDIN Eryfotona Actinica”

Good Molecules vs ISDIN routines for dry skin

See multi-brand routine · 99% fit

Good Molecules vs ISDIN routines for oily skin

See multi-brand routine · 96% fit

Good Molecules vs ISDIN routines for combination skin

See multi-brand routine · 96% fit

Questions and answers

Good Molecules or ISDIN: which is better?

Both brands are great choices, but Good Molecules is known for affordable and great value serums, while ISDIN is recognized for ultralight sunscreens.

What is the difference between Good Molecules and ISDIN?

Good Molecules and ISDIN offer different strengths, with Good Molecules focusing on affordable and fragrance-free products on this page, while ISDIN is known for its ultralight sunscreens and higher price points. Lovi shows that both brands offer Superior routines for dry, sensitive, acne-prone, mature skin, and skin with dark spots, but ISDIN provides a Superior routine fit for oily, combination, and dry sensitive skin.

Good Molecules or ISDIN for dry skin?

Both Good Molecules and ISDIN offer a routine fit rated as Superior for dry skin. The products on this page for Good Molecules also include options with a Superior fit level for dry skin, such as the Hyaluronic Acid Serum, Lightweight Daily Moisturizer, and Sheer Mineral Sunscreen SPF 30, while ISDIN features sunscreens like Eryfotona Actinica and Fusion Water that achieve a Superior fit for dry skin as well.

Good Molecules or ISDIN: which moisturizer is better?

Good Molecules offers affordable and hydrating moisturizers, while ISDIN provides lightweight moisturizers. For dry skin, Good Molecules has a Lovi fit level of Superior and ISDIN has a Lovi fit level of Superior.

Which is more affordable, Good Molecules or ISDIN?

Good Molecules is more affordable, offering budget-friendly and great value serums and moisturizers, whereas reviewers often note a high price point for ISDIN.

Good Molecules or ISDIN: which brand offers better options for dry sensitive skin?

Good Molecules offers better options for dry sensitive skin because Lovi rates its routine fit as High, whereas ISDIN provides a Superior fit. Reviewers also note that Good Molecules features gentle formulas with no fragrance listed across the products on this page, while ISDIN has a high price point and some products with strong fragrance.

How do the prices of Good Molecules and ISDIN compare according to reviewers?

According to reviewers, Good Molecules offers affordable products and great value, whereas ISDIN is often noted for having a high price point.

Good Molecules or ISDIN: which brand has better fragrance-free product options?

Good Molecules has better fragrance-free product options because every single product on its page lists no fragrance in its ingredients, whereas several ISDIN products contain added fragrance.

Good Molecules or ISDIN for oily skin?

For oily skin, ISDIN reaches a Superior routine fit while Good Molecules reaches High. Reviewers note that ISDIN does better for a lightweight and non-greasy texture, whereas Good Molecules provides an affordable price and great value.

Good Molecules or ISDIN: which sunscreen is better?

Both Good Molecules and ISDIN offer sunscreens that perform exceptionally well, with Lovi rating the Good Molecules Sheer Mineral Sunscreen SPF 30 and ISDIN's Eryfotona Actinica and Fusion Water as Superior for mature, sensitive, and dark spot-prone skin types. Reviewers frequently note that ISDIN sunscreens provide ultralight, skin-friendly, and makeup-friendly textures.

Good Molecules or ISDIN for sensitive skin?

Good Molecules and ISDIN both offer a gentle formula for sensitive skin, with Lovi fit levels of Superior for both brands on that skin type. Good Molecules is fragrance-free across the products on this page, whereas some ISDIN items may include fragrance.

Good Molecules or ISDIN for acne-prone skin?

Both Good Molecules and ISDIN are well suited for acne-prone skin, as Lovi rates both brands as having a Superior routine fit for this skin type. Good Molecules offers very gentle, affordable serums without fragrance on the products on this page, while ISDIN is noted for ultralight sunscreens.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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