Good Molecules vs ISDIN
Good Molecules and ISDIN are skincare brands, with the American brand founded in 2019 and owned by Beautylish, Inc., and the Spanish brand founded in 1975 and owned by Puig. Skincare enthusiasts love Good Molecules for its thoughtful range of serums, moisturizers, eye products, exfoliants, and more, which are carefully formulated with glycerin and hyaluronic acid, while they love ISDIN for its elegant moisturizers, advanced sunscreens, restorative serums, and targeted eye products, all united by thoughtfully balanced formulas. Both brands suit dry skin best, though the former also suits acne-prone skin and the latter suits sensitive skin. They differ in their core offerings and specific formulations, as the American brand features standout options like the Overnight Exfoliating Treatment, Sheer Mineral Sunscreen SPF 30, and Yerba Mate Wake Up Eye Gel, while the Spanish brand provides solutions such as Fusion Water, Eryfotona Actinica, and K-Ox Eyes.
Good Molecules is an American skincare brand founded in 2019 and owned by Beautylish, Inc..
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ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
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This page compares some of the most popular Good Molecules and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Good Molecules vs ISDIN products
People Say
Lightweight and non-greasy texture Often MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “absorbs quickly... zero irritation or tacky feeling — Good Molecules Discoloration Correcting Serum”
Affordable price and great value Mostly MentionedNot noted
- “best value for money — Good Molecules Hyaluronic Acid Serum”
- “great value — Good Molecules Niacinamide Serum”
Gentle formula for sensitive skin Often MentionedOften Mentioned
- “no skin purging — Good Molecules Gentle Retinol Cream”
- “leaves my face feeling clean without the drying — Good Molecules Hydrating Facial Cleansing Gel”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- “no excessive exfoliation — ISDIN Retinal Intense Serum”
Improves skin texture and smoothness Often MentionedOften Mentioned
- “skin looks like brand new baby skin — Good Molecules Overnight Exfoliating Treatment”
- “Leaves skin "baby soft," "super smooth," "polished feel" — Good Molecules Pineapple Exfoliating Powder”
- “skin looks smooth and healthy — ISDIN K-Ox Eyes”
- “I am more on a dehydrated side and this helps me look hydrated and smooth. — ISDIN Flavo-C Serum”
Hydration and plumping Often MentionedOften Mentioned
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
- “Skin feels intensely hydrated — ISDIN Hyaluronic Concentrate”
- “skin appears smooth and supple — Good Molecules Hyaluronic Acid Serum”
Brightens skin and fades dark spots Often MentionedOften Mentioned
- “scar on your chin doesn't look nearly as noticeable — Good Molecules Discoloration Correcting Serum”
- “skin looks more radiant — Good Molecules Niacinamide Brightening Toner”
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
- “skin looks immediately luminous — ISDIN K-Ox Eyes”
Unpleasant scent or fragrance concerns Sometimes NotedOften Mentioned
- “Strong bergamot smell — Good Molecules Super Peptide Serum”
- “weird faint smell — Good Molecules Gentle Retinol Cream”
- “purge happened in problem areas — Good Molecules Overnight Exfoliating Treatment”
- “smell is overpowering — ISDIN Eryfotona Actinica”
High price point Not notedOften Mentioned
- “very expensive — ISDIN Eryfotona Actinica”
Good Molecules vs ISDIN routines for dry skin
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Cleanser
La Roche-Posay Toleriane Hydrating Gentle Cleanser
Morning · Evening · Once a week
€21.95
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Hydrating Toner
Dear, Klairs Supple Preparation Unscented Toner
Morning
€16.89
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Moisturizer
Elizabeth Arden Advanced Ceramide Lift and Firm Night Cream
Morning · Evening · Once a week
€48.84
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SPF
Fusion Water
Morning
€24.98
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€11.83
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Cleansing Toner
ROUND LAB 1025 Dokdo Cleansing Water
Evening · Once a week
€13.99
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Serum or Treatment
Flavo-C Serum
Evening · Once a week
€45.97
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Nourishing Mask
LANEIGE Water Sleeping Mask_EX
Once a week
€33.90
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Cleanser
Hydrating Facial Cleansing Gel
Morning · Evening · Once a week
€46.05
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Hydrating Toner
Dear, Klairs Supple Preparation Unscented Toner
Morning
€16.89
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Moisturizer
Lightweight Daily Moisturizer
Morning · Evening · Once a week
€21.59
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SPF
Sheer Mineral Sunscreen SPF 30
Morning
€81.42
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€11.83
-
Cleansing Toner
ROUND LAB 1025 Dokdo Cleansing Water
Evening · Once a week
€13.99
-
Serum or Treatment
Daily Brightening Serum
Evening · Once a week
€47.00
-
Nourishing Mask
LANEIGE Water Sleeping Mask_EX
Once a week
€33.90
Good Molecules vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
€21.00
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€19.90
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Moisturizer
SKIN1004 Centella Cream
Morning · Evening · Once a week
€19.20
-
SPF
Eryfotona Actinica
Morning
€32.43
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€11.83
-
Cleansing Toner
Pixi Glow Tonic
Evening
€18.05
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€45.97
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€72.82
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Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
€15.72
-
Cleanser
Hydrating Facial Cleansing Gel
Morning · Evening · Once a week
€46.05
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€19.90
-
Moisturizer
Hyaluronic Acid Serum
Morning · Evening · Once a week
€16.98
-
SPF
Sheer Mineral Sunscreen SPF 30
Morning
€81.42
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€11.83
-
Cleansing Toner
Pixi Glow Tonic
Evening
€18.05
-
Serum or Treatment
Overnight Exfoliating Treatment
Evening · Once a week
€22.99
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€72.82
-
Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
€15.72
Good Molecules vs ISDIN routines for combination skin
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Cleanser
Dr. Althea Amino Acid Gentle Bubble Cleanser
Morning · Evening · Once a week
€16.50
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
SKIN1004 Centella Cream
Morning · Evening · Once a week
€19.20
-
SPF
Eryfotona Actinica
Morning
€32.43
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€11.83
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening · Once a week
€16.99
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€45.97
-
Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
€15.72
-
Cleanser
Hydrating Facial Cleansing Gel
Morning · Evening · Once a week
€46.05
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Hyaluronic Acid Serum
Morning · Evening · Once a week
€16.98
-
SPF
Sheer Mineral Sunscreen SPF 30
Morning
€81.42
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€11.83
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening · Once a week
€16.99
-
Serum or Treatment
Overnight Exfoliating Treatment
Evening · Once a week
€22.99
-
Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
€15.72
Questions and answers
Good Molecules or ISDIN: which is better?
Both Good Molecules and ISDIN are great choices, as each brand achieves a Superior Lovi fit for dry, sensitive, acne-prone, mature, and dark spot-prone skin types. Good Molecules is often preferred for its affordable price and great value, whereas ISDIN is well-liked for its lightweight and non-greasy textures.
What is the difference between Good Molecules and ISDIN?
Good Molecules and ISDIN both offer routines that fit dry, sensitive, acne-prone, and mature skin at a Superior level, but ISDIN provides a Superior routine fit for oily and combination skin where Good Molecules reaches a High level. ISDIN is mostly noted for ultralight sunscreens and lightweight moisturizers, while Good Molecules is known for affordable and great value serums.
Good Molecules or ISDIN for dry skin?
Both Good Molecules and ISDIN achieve a Superior Lovi routine fit for dry skin. Good Molecules offers budget-friendly products with no added fragrance across the products on this page, whereas ISDIN is known for ultralight, makeup-friendly sunscreens.
Good Molecules or ISDIN: which moisturizer is better?
Both Good Molecules and ISDIN offer great options, with Good Molecules favored for affordable and hydrating moisturizers, while ISDIN is noted for lightweight moisturizers. For dry skin, both brands achieve a Superior routine fit level.
Which is more affordable, Good Molecules or ISDIN?
Good Molecules is more affordable, as reviewers often mention its affordable price and great value, whereas ISDIN is frequently noted for its high price point.
Between Good Molecules and ISDIN, which brand offers fragrance-free products across its entire line on this page?
Good Molecules offers fragrance-free products across its entire line on this page, whereas ISDIN includes fragrance in some of its formulas.
How do the founding years and countries of origin compare between Good Molecules and ISDIN?
Good Molecules was founded in 2019 in the United States, while ISDIN was founded earlier in 1975 in Spain.
Which brand has better performance for routine fit specifically regarding oily acne-prone skin?
ISDIN has better performance for routine fit specifically regarding oily acne-prone skin, achieving a Superior Lovi fit level compared to Good Molecules' High fit level.
Good Molecules or ISDIN for oily skin?
For oily skin, ISDIN offers a Superior routine fit on this page, whereas Good Molecules provides a High fit. Reviewers note that ISDIN is particularly recognized for its lightweight and non-greasy textures.
Good Molecules or ISDIN: which sunscreen is better?
Both brands offer highly rated sunscreens on this page, with Good Molecules featuring its Sheer Mineral Sunscreen SPF 30 and ISDIN featuring options like Eryfotona Actinica and Fusion Water. Reviewers specifically highlight ISDIN for its ultralight and makeup-friendly sunscreens, while Good Molecules provides fragrance-free formulations.
Good Molecules or ISDIN for sensitive skin?
Both Good Molecules and ISDIN achieve a Superior Lovi fit level for sensitive skin. Reviewers note that Good Molecules offers very gentle, affordable serums, while ISDIN is known for its skin-friendly sunscreens, though some of its products contain fragrance.
Good Molecules or ISDIN for acne-prone skin?
Both Good Molecules and ISDIN offer a Superior Lovi routine fit for acne-prone skin. Good Molecules stands out for being more affordable, while ISDIN is noted for its ultralight sunscreens.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
Preparation and evaluation of anti-wrinkle cream containing saffron extract and avocado oil
Chemical peels for acne vulgaris: a systematic review of randomised controlled trials
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Hippophae rhamnoides oil-in-water (O/W) emulsion improves barrier function in healthy human subjects
Development and efficacy assessments of tea seed oil makeup remover
Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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