Anua Heartleaf Quercetin Pore Deep Cleansing Foam for acne-prone skin

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Questions and answers

What the research says

• Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability.

  Journal of Cosmetic Dermatology, 2024

• The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle.

  Journal of Drugs in Dermatology, 2023

• A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase.

  BioMed Research International, 2020

• Sodium cocoyl isethionate micelles are too large to penetrate stratum corneum aqueous pores, resulting in significant steric hindrance that prevents skin barrier perturbation and explains its skin mildness.

  Journal of Cosmetic Science, 2007

• Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

  American Journal of Clinical Dermatology, 2002

• Quercetin phospholipids 1% cream significantly reduced UV-, histamine-, and chemical-induced skin erythema (-10.05%) and mean wheal diameter in 30 healthy human volunteers, showing comparable efficacy to 1% dexchlorpheniramine cream.

  Clinical, Cosmetic and Investigational Dermatology, 2016

• Quercetin-loaded niosomes formulated with Span60-RH40 at a 9:11 mass ratio improved quercetin solubility, photostability, sustained release, and transdermal penetration, yielding a skin retention 2.95 times higher than quercetin solution.

  Molecules, 2019

• Optimized rutin-loaded glycerosomes formulated into a nanosunscreen gel demonstrated sustained drug release, greater skin permeation, good antioxidant activity, and better epidermal retention compared to the dermis, indicating high safety, stability, and sun protection factor values for topical administration.

  Gels, 2023

• Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients.

  CMAJ, 2010

• Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy.

  Journal of Cosmetic Dermatology, 2024

• Topical 5% benzoyl peroxide plus salicylic acid achieved the greatest lesion reduction at early 2 to 4 week time points compared to benzoyl peroxide, clindamycin, and combination benzoyl peroxide/clindamycin, while 5% benzoyl peroxide plus salicylic acid and combination benzoyl peroxide/clindamycin showed similar efficacy at 10 to 12 weeks in acne patients.

  Journal of the American Academy of Dermatology, 2010

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

Ingredients

Water, Glycerin, Cocamidopropyl Betaine, Sodium Cocoyl Isethionate, Houttuynia Cordata Extract, Quercetin, Sodium Chloride, Citric Acid, Sodium Benzoate, Potassium Sorbate, Butylene Glycol, 1,2-Hexanediol, Caprylyl Glycol, Disodium Edta, Salicylic Acid, Hyaluronic Acid, Allantoin, Panthenol, Phenoxyethanol, Ethylhexylglycerin

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.