Hada Labo vs Sesderma
Hada Labo and Sesderma are distinguished skincare brands that bring unique scientific approaches to daily routines. Hada Labo is a Japanese line known for hydrating toners, gentle makeup removers, and nourishing moisturizers powered by advanced formulas, while Sesderma is a Spanish house celebrated for advanced serums and meticulously engineered formulations. The former suits dry and acne-prone skin best, whereas the latter is ideal for sensitive, hyperpigmented, and aging skin. While both rely on harmonious ingredients to support a healthy complexion, they differ in their foundational origins and primary concentrations.
Hada Labo is a Japanese skincare brand founded in 2004 and owned by Rohto Pharmaceutical Co., Ltd..
en.wikipedia.orghadalabosa.co.zahadalabotokyo.pl
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Hada Labo and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Hada Labo vs Sesderma products
Questions and answers
Hada Labo or Sesderma: which is better?
Hada Labo provides a Superior fit for dry skin and offers deep hydration with fragrance-free hyaluronic acid formulas. Sesderma features targeted options like Azelac RU Serum for dark spots, though it contains fragrance and is rated Low for dry skin.
What is the difference between Hada Labo and Sesderma?
Hada Labo focuses on fragrance-free hyaluronic acid toners and moisturizers that give deep hydration, fitting dry and acne-prone skin best with a Superior fit. In contrast, Sesderma offers a serum with fragrance that helps with dark spots, though it has a Low fit for dry skin.
Which is more affordable, Hada Labo or Sesderma?
Hada Labo is more affordable, offering products on this page noted for value and versatility, while Sesderma features targeted serums like Azelac RU Serum at higher price points.
Which causes fewer breakouts, Hada Labo or Sesderma?
Hada Labo is a better choice for acne-prone skin, as Lovi rates its products as High or Average for acne-prone skin, whereas Sesderma's Azelac RU Serum is rated Average for acne-prone skin and reviewers mention that Hada Labo helps with gentle formulations.
Which brand was founded earlier and in which country, Hada Labo or Sesderma?
Sesderma was founded earlier in 1989 in Spain, whereas Hada Labo was founded in 2004 in Japan.
How do the fragrance profiles compare between Hada Labo and Sesderma products?
Hada Labo products on this page list no fragrance, whereas the Sesderma product contains fragrance. This makes Hada Labo a better choice if you prefer fragrance-free skincare.
Which brand offers more products for dry skin according to the Lovi fit levels?
Hada Labo offers more products for dry skin on this page, with multiple items rated Superior or High in Lovi fit levels, whereas Sesderma has only one product which is rated Low for dry skin.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Preparation and characterization of a lecithin nanoemulsion as a topical delivery system
The anti-wrinkles properties of sodium acetylated hyaluronate
Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Combined Effect of Silybin and Sodium Acetylated Hyaluronate on UV-Induced Photoaging
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-

Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.








