Hada Labo vs Sesderma
Hada Labo and Sesderma are distinguished skincare brands that offer thoughtfully engineered daily care. The Japanese brand is known for hydrating toners, gentle makeup removers, and nourishing moisturizers driven by advanced formulas, while the Spanish brand is beloved for advanced serums and meticulously engineered formulas. Hada Labo suits dry skin and combination skin best, whereas Sesderma suits sensitive, hyperpigmented, and aging skin types best. Both brands differ primarily in their regional heritage, founding years, and specific ingredient philosophies.
Hada Labo is a Japanese skincare brand founded in 2004 and owned by Rohto Pharmaceutical Co., Ltd..
en.wikipedia.orghadalabosa.co.zahadalabotokyo.pl
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Hada Labo and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Hada Labo vs Sesderma products
Questions and answers
Hada Labo or Sesderma: which is better?
Hada Labo is better suited for dry and sensitive skin thanks to its fragrance-free hyaluronic acid formulas, whereas Sesderma offers targeted options like Azelac RU Serum for dark spots and acne-prone skin.
What is the difference between Hada Labo and Sesderma?
Hada Labo focuses on fragrance-free hydration using hyaluronic acid across a wide range of toners and cleansers, whereas Sesderma offers a single serum that contains fragrance and targets dark spots and acne-prone skin.
Which is more affordable, Hada Labo or Sesderma?
Hada Labo is often considered for value and versatility on this page, while Sesderma does not list value highlights.
Which causes fewer breakouts, Hada Labo or Sesderma?
Hada Labo products on this page are rated High for acne-prone skin, whereas Sesderma's Azelac RU Serum is rated Average for acne-prone skin, meaning Hada Labo may cause fewer breakouts for acne-prone shoppers.
Which brand provides products with no fragrance, Hada Labo or Sesderma?
Hada Labo provides products with no fragrance, as every product on this page lists no fragrance in its ingredients, whereas Sesderma includes fragrance in its products.
How do the founding years and countries of origin compare between Hada Labo and Sesderma?
Hada Labo was founded in Japan in 2004, whereas Sesderma was founded earlier in Spain in 1989.
Which brand offers a larger variety of products on this page for dry skin?
Hada Labo offers a larger variety of products on this page for dry skin, including the Gokujyun Lotion and Gokujyun Cleansing Oil which Lovi rates as Superior. Sesderma features only one product on the page, Azelac RU Serum, which Lovi rates as Low for dry skin.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Preparation and characterization of a lecithin nanoemulsion as a topical delivery system
The anti-wrinkles properties of sodium acetylated hyaluronate
Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Combined Effect of Silybin and Sodium Acetylated Hyaluronate on UV-Induced Photoaging
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sof铆a Perea P茅rez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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