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Hada Labo vs Sesderma

Hada Labo and Sesderma are distinguished skincare brands that bring unique scientific approaches to daily routines. Hada Labo is a Japanese line known for hydrating toners, gentle makeup removers, and nourishing moisturizers powered by advanced formulas, while Sesderma is a Spanish house celebrated for advanced serums and meticulously engineered formulations. The former suits dry and acne-prone skin best, whereas the latter is ideal for sensitive, hyperpigmented, and aging skin. While both rely on harmonious ingredients to support a healthy complexion, they differ in their foundational origins and primary concentrations.

Hada Labo is a Japanese skincare brand founded in 2004 and owned by Rohto Pharmaceutical Co., Ltd..

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Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

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This page compares some of the most popular Hada Labo and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Questions and answers

Hada Labo or Sesderma: which is better?

Hada Labo is generally better for dry, acne-prone, and oily skin, with Lovi giving its products ratings up to Superior. Hyaluronic acid helps provide deep hydration, although some users report sticky finishes.

Dermatologic Therapy, 2022

What is the difference between Hada Labo and Sesderma?

Hada Labo is a Japanese brand founded in 2004 that focuses heavily on gentle, fragrance-free hydration with key ingredients like hyaluronic acid, making it best suited for dry, acne-prone, and oily skin types. In contrast, Sesderma is a Spanish brand founded in 1989 whose products on this page, such as the Azelac RU Serum, include fragrance and are rated with a Low fit for dry skin.

Dermatologic Therapy, 2022

Which is more affordable, Hada Labo or Sesderma?

Hada Labo is known for value and versatility across the products on this page, whereas Sesderma focuses on specialized treatments like its Azelac RU Serum. Topical hyaluronic acid helps provide deep hydration in Hada Labo formulas.

Dermatologic Therapy, 2022

Which causes fewer breakouts, Hada Labo or Sesderma?

Hada Labo is unlikely to cause breakouts as every product on this page lists no fragrance, whereas Sesderma's serum contains fragrance. Reviewers note that Hada Labo provides deep hydration with lightweight toners, helping avoid clogged pores.

How do the founding years and countries of origin compare between Hada Labo and Sesderma?

Hada Labo was founded in 2004 in Japan, whereas Sesderma was founded in 1989 in Spain.

Which brand offers products with no fragrance in their ingredients according to the page?

Hada Labo offers products with no fragrance on this page, as every product lists no fragrance in its ingredients.

What specific skin types does the Azelac RU Serum from Sesderma fit best?

Lovi rates Azelac RU Serum from Sesderma as a High fit for acne-prone skin, skin with dark spots, and combination skin.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.