Hada Labo vs Sesderma
Hada Labo and Sesderma are distinguished skincare brands that bring unique scientific approaches to daily routines. Hada Labo is a Japanese line known for hydrating toners, gentle makeup removers, and nourishing moisturizers powered by advanced formulas, while Sesderma is a Spanish house celebrated for advanced serums and meticulously engineered formulations. The former suits dry and acne-prone skin best, whereas the latter is ideal for sensitive, hyperpigmented, and aging skin. While both rely on harmonious ingredients to support a healthy complexion, they differ in their foundational origins and primary concentrations.
Hada Labo is a Japanese skincare brand founded in 2004 and owned by Rohto Pharmaceutical Co., Ltd..
en.wikipedia.orghadalabosa.co.zahadalabotokyo.pl
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Hada Labo and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Hada Labo vs Sesderma products
Questions and answers
Hada Labo or Sesderma: which is better?
Hada Labo is better for dry, acne-prone, and mature skin, where Lovi rates its products up to Superior fit. The products on this page help provide deep hydration with hyaluronic acid and are fragrance-free.
What is the difference between Hada Labo and Sesderma?
Hada Labo offers fragrance-free toners, cleansers, and gels featuring hyaluronic acid that Lovi rates Superior for dry skin, whereas Sesderma features a serum with fragrance that Lovi rates Low for dry skin.
Which is more affordable, Hada Labo or Sesderma?
Hada Labo is more affordable, as reviewers often mention its value and versatility across the products on this page. Sesderma features a single serum on the page and does not highlight budget-friendly value.
Which causes fewer breakouts, Hada Labo or Sesderma?
Hada Labo is a better choice for avoiding breakouts because every product on this page lists no fragrance, whereas the Sesderma product includes fragrance which may irritate breakout-prone skin.
Which brand offers fragrance-free products, and how do they compare in terms of scent?
Hada Labo offers fragrance-free products, as every item on this page lists no fragrance in its ingredients. In contrast, Sesderma includes fragrance in its products on this page.
What are the founding years and countries of origin for Hada Labo and Sesderma?
Hada Labo was founded in 2004 in Japan, while Sesderma was founded in 1989 in Spain.
How do the Lovi fit levels for dry skin compare between Hada Labo's Gokujyun Lotion and Sesderma's Azelac RU Serum?
Hada Labo's Gokujyun Lotion achieves a Superior Lovi fit for dry skin, whereas Sesderma's Azelac RU Serum only reaches a Low fit.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Preparation and characterization of a lecithin nanoemulsion as a topical delivery system
The anti-wrinkles properties of sodium acetylated hyaluronate
Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Combined Effect of Silybin and Sodium Acetylated Hyaluronate on UV-Induced Photoaging
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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