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Hada Labo vs Sesderma

Rated by Lovi 路 Unbiased, science-based skincare AI trained on real user outcomes 路 How the Fit score works

Hada Labo and Sesderma are distinguished skincare brands that bring unique scientific approaches to daily routines. Hada Labo is a Japanese line known for hydrating toners, gentle makeup removers, and nourishing moisturizers powered by advanced formulas, while Sesderma is a Spanish house celebrated for advanced serums and meticulously engineered formulations. The former suits dry and acne-prone skin best, whereas the latter is ideal for sensitive, hyperpigmented, and aging skin. While both rely on harmonious ingredients to support a healthy complexion, they differ in their foundational origins and primary concentrations.

Hada Labo is a Japanese skincare brand founded in 2004 and owned by Rohto Pharmaceutical Co., Ltd..

en.wikipedia.orghadalabosa.co.zahadalabotokyo.pl

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Hada Labo and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Hada Labo vs Sesderma products

Questions and answers

Hada Labo or Sesderma: which is better?

Hada Labo is a better fit than Sesderma for dry skin, where Lovi rates its products as Superior. Topical sodium hyaluronate helps improve skin hydration and signs of aging.

Dermatologic Therapy, 2022

What is the difference between Hada Labo and Sesderma?

Hada Labo is a Japanese brand founded in 2004 that focuses heavily on fragrance-free hyaluronic acid hydration, while Sesderma is a Spanish brand founded in 1989 that offers targeted formulas like the Azelac RU Serum with fragrance. Topical hyaluronic acid helps improve skin quality and hydration.

Dermatologic Therapy, 2022

Which is more affordable, Hada Labo or Sesderma?

Hada Labo is more affordable, offering products noted for value and versatility alongside deep hydration. Sesderma features higher-priced specialty options like its Azelac RU Serum.

Which causes fewer breakouts, Hada Labo or Sesderma?

Hada Labo products on this page help provide deep hydration with hyaluronic acid and are fragrance-free, making them less likely to trigger irritation compared to fragranced formulas. However, reviewers note that breakouts and clogged pores may sometimes occur with some products on this page.

Dermatologic Therapy, 2022

Which brand has been established longer, Hada Labo or Sesderma?

Sesderma has been established longer, having been founded in Spain in 1989, whereas Hada Labo was founded in Japan in 2004.

Do Hada Labo and Sesderma products contain fragrance?

Hada Labo products on this page list no fragrance, whereas the Azelac RU Serum from Sesderma contains fragrance.

Which skin types does Hada Labo fit best compared to Sesderma?

Hada Labo fits dry skin, acne-prone skin, and oily skin best, while the products on this page for Sesderma do not have a defined best-fit skin type. Hyaluronic acid helps provide deep hydration across the Hada Labo range.

Dermatologic Therapy, 2022

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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