Sesderma skincare
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
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Sesderma is beloved for its advanced serums and meticulously engineered formulas. Its products suit sensitive, hyperpigmented, and aging skin types best. The standout products for particular concerns include the Azelac RU Serum for acne-prone skin. Its botanical extracts and active compounds work synergistically to refine skin texture and promote a radiant complexion.
This page covers some of the most popular Sesderma products; for the whole Sesderma range, with a fit score for every product, use the Lovi app.
Sesderma serums and treatments
Questions and answers
Is Sesderma worth it?
Sesderma rates Superior for dry, oily, sensitive, combination, and acne-prone skin, making it a strong choice for these skin types. The Sesderma products on this page include fragrance.
What are Sesderma's best products?
Sesderma offers the Azelac RU Serum, which Lovi rates High for acne-prone skin, dark spots, and combination skin. Lovi rates the Sesderma-focused routine Superior for dry, oily, sensitive, combination, and acne-prone skin.
Does Sesderma cause breakouts?
No, Azelac RU Serum helps manage blemishes, and Lovi rates acne-prone skin High for this product. Sesderma-focused routines also rate Superior for acne-prone skin.
Is Sesderma fragrance-free?
No, the Sesderma products on this page contain fragrance, as seen with Azelac RU Serum.
What are the key ingredients in Sesderma products?
Sesderma uses azelaic acid and 4-butylresorcinol in its Azelac RU Serum to target dark spots and acne-prone areas. Azelaic acid helps manage blemishes, while 4-butylresorcinol reduces skin pigmentation.
How do I build a Sesderma skincare routine?
To build a Sesderma skincare routine, you can use the Azelac RU Serum, which helps care for various skin concerns. Lovi rates the Sesderma-focused routine Superior for dry, oily, sensitive, combination, and acne-prone skin.
Where can I buy Sesderma, and how much does it cost?
Sesderma products are available through stores in Italy. Prices on this page range from €46.00 to €46.00.
What are good alternatives to Sesderma?
Good alternatives to Sesderma include ISDIN, Heliocare, Theramid, Mesoestetic, Endocare, and ISDIN Isdinceutics. These similar brands also have pages on Lovi.
Sesderma vs ISDIN: which is better?
Both Sesderma and ISDIN offer great options, as Lovi rates a Sesderma-focused routine as Superior for dry, oily, sensitive, combination, and acne-prone skin, matching the Superior fit levels of an ISDIN-focused routine across all these skin types.
Who owns Sesderma, and where is it from?
Sesderma is a Spanish brand founded in 1989, owned by Grupo Sesderma since 2026.
Is Sesderma cruelty-free?
PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list Sesderma as cruelty-free.
Research behind Sesderma's key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Behind these ratings
Lovi rates every product from its full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.

