Hada Labo vs Sesderma
Hada Labo and Sesderma are well-regarded skincare brands known for their nurturing toners, gentle makeup removers, deeply nourishing moisturizers, and advanced serums crafted from advanced formulas. The Japanese brand suits dry skin and dry sensitive skin best, while the Spanish brand suits sensitive, hyperpigmented, and aging skin types best. Both offer standout products like the Gokujyun Lotion for acne-prone skin, alongside targeted formulations such as the Shirojyun Premium Whitening Lotion, the Gokujun Premium, and the Azelac RU Serum. Ultimately, they differ in their foundational origins, specific ingredient approaches, and the distinct complexion concerns they address.
Hada Labo is a Japanese skincare brand founded in 2004 and owned by Rohto Pharmaceutical Co., Ltd..
en.wikipedia.orghadalabosa.co.zahadalabotokyo.pl
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Hada Labo and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Questions and answers
Hada Labo or Sesderma: which is better?
Hada Labo is generally better for dry, sensitive, and general skin needs on this page, as its fragrance-free products focus on deep hydration with hyaluronic acid. Meanwhile, Sesderma offers targeted care with products like Azelac RU Serum, but it contains fragrance and has a lower fit for dry skin types.
What is the difference between Hada Labo and Sesderma?
Hada Labo is a Japanese brand founded in 2004 that fits dry, dry sensitive, and sensitive skin best with its fragrance-free hyaluronic acid products, whereas Sesderma is a Spanish brand founded in 1989 whose Azelac RU Serum contains fragrance and rates low for dry skin types.
Which is more affordable, Hada Labo or Sesderma?
The products on this page by Hada Labo offer good value and versatility, whereas Sesderma does not mention affordability.
Which causes fewer breakouts, Hada Labo or Sesderma?
Hada Labo is a better choice for avoiding breakouts because the products on this page are fragrance-free and feature gentle formulas, whereas the Sesderma product contains fragrance which may irritate acne-prone skin.
How does the Lovi fit level of Hada Labo's Gokujyun Lotion compare for dry skin versus Sesderma's Azelac RU Serum?
For dry skin, Hada Labo's Gokujyun Lotion has a Superior Lovi fit level, whereas Sesderma's Azelac RU Serum has a Low fit level. Topical hyaluronic acid helps improve skin quality and hydration.
Which brand has products that are fragrance-free, Hada Labo or Sesderma?
Hada Labo has products that are fragrance-free, as every product on this page lists no fragrance in its ingredients, while Sesderma includes fragrance in its Azelac RU Serum.
When was Hada Labo founded and which company owns it?
Hada Labo was founded in 2004 in Japan and is owned by Rohto Pharmaceutical Co., Ltd..
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Preparation and characterization of a lecithin nanoemulsion as a topical delivery system
The anti-wrinkles properties of sodium acetylated hyaluronate
Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Combined Effect of Silybin and Sodium Acetylated Hyaluronate on UV-Induced Photoaging
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-

Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sof铆a Perea P茅rez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.







