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Hada Labo vs Sesderma

Hada Labo and Sesderma are distinguished skincare brands that bring unique scientific approaches to daily routines. Hada Labo is a Japanese line known for hydrating toners, gentle makeup removers, and nourishing moisturizers powered by advanced formulas, while Sesderma is a Spanish house celebrated for advanced serums and meticulously engineered formulations. The former suits dry and acne-prone skin best, whereas the latter is ideal for sensitive, hyperpigmented, and aging skin. While both rely on harmonious ingredients to support a healthy complexion, they differ in their foundational origins and primary concentrations.

Hada Labo is a Japanese skincare brand founded in 2004 and owned by Rohto Pharmaceutical Co., Ltd..

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Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

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This page compares some of the most popular Hada Labo and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Questions and answers

Hada Labo or Sesderma: which is better?

Hada Labo is generally a better fit than Sesderma for everyday hydration and sensitive skin, as the products on this page feature fragrance-free hyaluronic acid formulations that help deliver deep moisture.

Dermatologic Therapy, 2022

What is the difference between Hada Labo and Sesderma?

Hada Labo focuses on fragrance-free hydration with key ingredients like hyaluronic acid, whereas Sesderma includes fragrance in its serum on this page.

Dermatologic Therapy, 2022

Which is more affordable, Hada Labo or Sesderma?

Hada Labo stands out for its affordability, as its products on this page frequently receive positive shopper reviews for offering great value and versatility.

Which causes fewer breakouts, Hada Labo or Sesderma?

Hada Labo is a better choice for avoiding breakouts, as the products on this page fit acne-prone skin up to a High level and have fragrance-free formulas, whereas Sesderma's Azelac RU Serum contains fragrance.

How do the founding years and countries of origin compare between Hada Labo and Sesderma?

Hada Labo was founded in Japan in 2004, whereas Sesderma was founded in Spain in 1989.

Which brand offers products specifically formulated without fragrance, Hada Labo or Sesderma?

Hada Labo offers products specifically formulated without fragrance, as every product on this page lists no fragrance in its ingredients, whereas Sesderma includes fragrance in its serum.

How does the Lovi fit level for dry skin compare between Hada Labo's toners and Sesderma's Azelac RU Serum?

Hada Labo toners generally have a Superior or High Lovi fit for dry skin, whereas Sesderma's Azelac RU Serum only has a Low fit for dry skin. Topical hyaluronic acid found in Hada Labo products helps improve dry skin quality.

Dermatologic Therapy, 2022

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.