Hada Labo vs Sesderma
Hada Labo and Sesderma are trusted skincare brands that offer thoughtfully crafted formulas designed to support healthy skin. The Japanese brand is known for its targeted toners, gentle makeup removers, and deeply hydrating moisturizers, whereas the Spanish brand is beloved for its advanced serums. Both brands suit sensitive skin types best, though they differ through their distinct ingredients and regional origins.
Hada Labo is a Japanese skincare brand founded in 2004 and owned by Rohto Pharmaceutical Co., Ltd..
en.wikipedia.orghadalabosa.co.zahadalabotokyo.pl
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Hada Labo and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Hada Labo vs Sesderma products
Questions and answers
Hada Labo or Sesderma: which is better?
Hada Labo is better for deep hydration and fragrance-free routines, as the products on this page provide reliable moisture with hyaluronic acid, while Sesderma offers a serum that includes fragrance.
What is the difference between Hada Labo and Sesderma?
Hada Labo is a Japanese brand founded in 2004 that features fragrance-free hyaluronic acid products like toners and gels which Lovi rates as Superior or High for dry and sensitive skin. In contrast, Sesderma is a Spanish brand founded in 1989 whose Azelac RU Serum contains fragrance and receives lower fit levels for dry skin.
Which is more affordable, Hada Labo or Sesderma?
Hada Labo is more affordable, offering high-value and versatile skincare options compared to Sesderma.
Which causes fewer breakouts, Hada Labo or Sesderma?
Hada Labo products on this page are generally associated with providing gentle, fragrance-free hydration, although some users note breakouts and clogged pores, while the Azelac RU Serum from Sesderma may carry a risk of breakouts for sensitive skin.
How do the founding years and origins of Hada Labo and Sesderma compare?
Hada Labo was founded in Japan in 2004, whereas Sesderma was founded earlier in Spain in 1989.
Which brand offers products with no fragrance in their ingredients, Hada Labo or Sesderma?
Hada Labo offers products with no fragrance on this page, as every single product lists no fragrance in its ingredients, whereas Sesderma's Azelac RU Serum includes fragrance.
What is the Lovi fit level of Hada Labo's Gokujyun Lotion for dry skin compared to Sesderma's Azelac RU Serum for dry skin?
Hada Labo's Gokujyun Lotion has a Superior Lovi fit level for dry skin, whereas Sesderma's Azelac RU Serum has a Low fit level for dry skin.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Preparation and characterization of a lecithin nanoemulsion as a topical delivery system
The anti-wrinkles properties of sodium acetylated hyaluronate
Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Combined Effect of Silybin and Sodium Acetylated Hyaluronate on UV-Induced Photoaging
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sof铆a Perea P茅rez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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