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Hada Labo vs Sesderma

Hada Labo and Sesderma are distinguished skincare brands that bring unique scientific approaches to daily routines. Hada Labo is a Japanese line known for hydrating toners, gentle makeup removers, and nourishing moisturizers powered by advanced formulas, while Sesderma is a Spanish house celebrated for advanced serums and meticulously engineered formulations. The former suits dry and acne-prone skin best, whereas the latter is ideal for sensitive, hyperpigmented, and aging skin. While both rely on harmonious ingredients to support a healthy complexion, they differ in their foundational origins and primary concentrations.

Hada Labo is a Japanese skincare brand founded in 2004 and owned by Rohto Pharmaceutical Co., Ltd..

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Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

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This page compares some of the most popular Hada Labo and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Questions and answers

Hada Labo or Sesderma: which is better?

Hada Labo is better for dry, acne-prone, and oily acne-prone skin types, offering fragrance-free toners and cleansers that help with deep hydration. Sodium hyaluronate in these products helps improve skin quality and signs of aging.

Dermatologic Therapy, 2022

What is the difference between Hada Labo and Sesderma?

Hada Labo is a Japanese brand founded in 2004 that focuses heavily on fragrance-free hyaluronic acid hydration, whereas Sesderma is a Spanish brand founded in 1989 whose products on this page contain fragrance. Lovi rates Hada Labo with superior fits for dry skin, while Sesderma offers specialized serums like Azelac RU Serum for dark spots.

Dermatologic Therapy, 2022

Which is more affordable, Hada Labo or Sesderma?

Hada Labo is more affordable because reviewers on the page frequently mention its value and versatility.

Which causes fewer breakouts, Hada Labo or Sesderma?

Hada Labo is listed with specific fit levels for acne-prone skin, while Sesderma has only one product on this page, Azelac RU Serum, with a High fit for acne-prone skin. Reviewers mention that Hada Labo products sometimes cause breakouts and clogged pores, but the page does not provide enough comparative breakout data for a definitive choice.

How do the founding years and countries of origin compare between Hada Labo and Sesderma?

Hada Labo was founded in 2004 in Japan, whereas Sesderma was founded in 1989 in Spain.

Which brand has more fragrance-free products listed on the page, Hada Labo or Sesderma?

Hada Labo has more fragrance-free products on the page, as every product listed for the brand contains no fragrance, whereas the Azelac RU Serum by Sesderma includes fragrance.

What are the main positive review points mentioned for Hada Labo products?

Reviewers frequently mention deep hydration and moisturization as the main positive points for the products on this page. They also often note gentle, fragrance-free formulations, good value and versatility, lightweight and fast-absorbing toners, and brightening and dark spot reduction.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.