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CeraVe vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

CeraVe and Sesderma are trusted skincare brands that offer reliable daily routines and advanced treatments, respectively. The American brand, founded in 2005, is known for dependable moisturizers, gentle cleansers, targeted serums, and protective sunscreens enriched with hyaluronic acid and glycerin, suiting mature and dry skin best. Meanwhile, the Spanish brand, founded in 1989, is beloved for advanced serums and meticulously engineered formulas that suit sensitive, hyperpigmented, and aging skin. While both deliver proven results through active compounds and botanical extracts, the former relies on barrier-supporting ingredients like glycerin, whereas the latter specializes in synergistic treatments like the Azelac RU Serum.

CeraVe is an American skincare brand founded in 2005 and owned by L'Oréal since 2017.

en.wikipedia.orghappi.comloreal-finance.comcerave.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular CeraVe and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular CeraVe vs Sesderma products

CeraVe vs Sesderma serums and treatments

Questions and answers

CeraVe or Sesderma: which is better?

CeraVe has a much broader lineup of fragrance-free products on this page and fits mature, dry, and acne-prone skin best. Sesderma offers fewer options here, with only Azelac RU Serum listed, and its formula includes fragrance.

What is the difference between CeraVe and Sesderma?

CeraVe offers a broad range of fragrance-free cleansers, moisturizers, and serums with a Superior or High Lovi fit for mature, dry, and acne-prone skin, while Sesderma features just one serum with fragrance listed on this page.

Which is more affordable, CeraVe or Sesderma?

This page does not provide pricing or affordability information for either CeraVe or Sesderma.

Which causes fewer breakouts, CeraVe or Sesderma?

CeraVe helps provide gentle, fragrance-free products on this page with high-fit options for acne-prone skin, whereas Sesderma lists fewer options and includes fragrance, which may sometimes irritate sensitive or acne-prone skin.

How do the founding years and countries of origin compare between CeraVe and Sesderma?

CeraVe was founded in 2005 in the United States, whereas Sesderma was founded in 1989 in Spain.

Which brand offers a greater variety of products for dry skin according to the page?

CeraVe offers a greater variety of products for dry skin on this page, including multiple cleansers and moisturizers with High to Superior Lovi fit levels for dry skin. Sesderma features only a single serum on the page, which has a Low fit level for dry skin.

Do both CeraVe and Sesderma products include fragrance-free options?

Yes, CeraVe offers fragrance-free options across the products on this page, while Sesderma does not list any fragrance-free options for its products.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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