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Hada Labo vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Hada Labo and Sesderma are distinguished skincare brands that bring unique scientific approaches to daily routines. Hada Labo is a Japanese line known for hydrating toners, gentle makeup removers, and nourishing moisturizers powered by advanced formulas, while Sesderma is a Spanish house celebrated for advanced serums and meticulously engineered formulations. The former suits dry and acne-prone skin best, whereas the latter is ideal for sensitive, hyperpigmented, and aging skin. While both rely on harmonious ingredients to support a healthy complexion, they differ in their foundational origins and primary concentrations.

Hada Labo is a Japanese skincare brand founded in 2004 and owned by Rohto Pharmaceutical Co., Ltd..

en.wikipedia.orghadalabosa.co.zahadalabotokyo.pl

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Hada Labo and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Hada Labo vs Sesderma products

Questions and answers

Hada Labo or Sesderma: which is better?

Hada Labo is generally better for dry, acne-prone, and mature skin because the products on this page offer deep hydration with hyaluronic acid and fragrance-free formulas, whereas Sesderma's serum contains fragrance and has a low fit for dry skin. Topical hyaluronic acid helps improve skin quality and hydration.

Dermatologic Therapy, 2022

What is the difference between Hada Labo and Sesderma?

Hada Labo is a Japanese brand founded in 2004 that focuses heavily on fragrance-free hyaluronic acid hydration, fitting dry, acne-prone, and mature skin best. In contrast, Sesderma is a Spanish brand founded in 1989 whose featured Azelac RU Serum contains fragrance and targets dark spots and acne-prone skin with lower fit levels for dry skin.

Dermatologic Therapy, 2022

Which is more affordable, Hada Labo or Sesderma?

Hada Labo offers value and versatility according to reviewers on this page, whereas Sesderma has no such mention. The products on this page for Hada Labo provide affordable options across multiple items, while Sesderma features only a single serum.

Which causes fewer breakouts, Hada Labo or Sesderma?

Hada Labo products on this page list no fragrance, which helps minimize irritation, whereas Sesderma includes fragrance in its serum.

Which brand offers products specifically formulated without fragrance, Hada Labo or Sesderma?

Hada Labo is the better choice for fragrance-free skincare because every product on this page lists no fragrance in its ingredients, whereas Sesderma includes fragrance in its serum.

How do the founding years and countries of origin compare between Hada Labo and Sesderma?

Hada Labo was founded in Japan in 2004, whereas Sesderma was founded in Spain in 1989.

Which brand has more product options listed for dry skin, Hada Labo or Sesderma?

Hada Labo has significantly more product options listed for dry skin, with multiple toners, a cleansing oil, and a moisturizer showing Superior or High Lovi fit levels. In contrast, Sesderma only features one product on this page, the Azelac RU Serum, which has a Low Lovi fit for dry skin.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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