Sesderma skincare
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
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Sesderma is beloved for its advanced serums and meticulously engineered formulas. Its products suit sensitive, hyperpigmented, and aging skin types best. The standout products for particular concerns include the Azelac RU Serum for acne-prone skin. Its botanical extracts and active compounds work synergistically to refine skin texture and promote a radiant complexion.
This page covers some of the most popular Sesderma products; for the whole Sesderma range, with a fit score for every product, use the Lovi app.
Sesderma serums and treatments
Questions and answers
Is Sesderma worth it?
Yes, Sesderma is worth it for shoppers seeking effective care, as Lovi rates Sesderma-focused routines Superior for dry, oily, sensitive, combination, and acne-prone skin. Azelac RU Serum helps with acne-prone skin and dark spots.
What are Sesderma's best products?
Sesderma offers the Azelac RU Serum, which Lovi rates High for acne-prone skin, dark spots, and combination skin. For overall care, a Sesderma-focused routine reaches a Superior fit for dry, oily, sensitive, combination, and acne-prone skin types.
Does Sesderma cause breakouts?
Sesderma is unlikely to cause breakouts, as the Azelac RU Serum on this page helps care for acne-prone skin and Lovi rates it High for that skin type. Azelaic acid helps manage acne by reducing blemishes.
Is Sesderma fragrance-free?
No, the Sesderma products on this page include fragrance, as seen in the Azelac RU Serum.
What are the key ingredients in Sesderma products?
Azelac RU Serum contains azelaic acid, which helps fade dark spots and manage breakouts. Lovi rates this serum High for skin with dark spots and acne-prone skin.
How do I build a Sesderma skincare routine?
To build a Sesderma skincare routine, apply the Azelac RU Serum as the core step. Lovi rates Sesderma-focused routines as Superior for dry skin, oily skin, sensitive skin, combination skin, and acne-prone skin.
What are good alternatives to Sesderma?
Good alternatives to Sesderma include ISDIN, Heliocare, Theramid, Mesoestetic, Endocare, and ISDIN Isdinceutics, which all have pages on Lovi. For dry, oily, sensitive, combination, and acne-prone skin, Sesderma-focused routines and ISDIN-focused routines both rate Superior.
Sesderma vs ISDIN: which is better?
Sesderma and ISDIN both offer a Superior fit for dry, oily, sensitive, combination, and acne-prone skin types. Shoppers can find that both brands perform at the highest level across these shared skin needs on Lovi.
Who owns Sesderma, and where is it from?
Sesderma is a Spanish brand founded in 1989, owned by Grupo Sesderma since 2026.
Is Sesderma cruelty-free?
PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list Sesderma as cruelty-free.
Research behind Sesderma's key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Behind these ratings
Lovi rates every product from its full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sof铆a Perea P茅rez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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