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SkinCeuticals vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

SkinCeuticals and Sesderma are esteemed skincare brands that offer advanced serums, nourishing moisturizers, gentle cleansers, and soothing eye products. The American brand is loved for its glycerin, hyaluronic acid, and dimethicone formulations that suit dry skin and dry sensitive skin best, while the Spanish brand is beloved for its meticulous engineering that suits sensitive, hyperpigmented, and aging skin types best. Both brands differ in their specific botanical extracts, active compounds, and restorative elements designed to target concerns like acne, dark spots, and mature skin.

SkinCeuticals is an American skincare brand founded in 1994 and owned by L'Oréal since 2005.

loreal.comskinceuticals-za.compitchbook.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular SkinCeuticals and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular SkinCeuticals vs Sesderma products

SkinCeuticals vs Sesderma serums and treatments

Questions and answers

SkinCeuticals or Sesderma: which is better?

SkinCeuticals offers a much wider variety of products on this page across multiple skin types compared to Sesderma, which only lists one product. Lovi rates SkinCeuticals as having High to Superior fit levels for dry and sensitive skin types.

What is the difference between SkinCeuticals and Sesderma?

SkinCeuticals offers a wide range of products with High or Superior Lovi fit levels across multiple skin types, whereas Sesderma currently features only Azelac RU Serum on this page with varying fit levels.

Which is more affordable, SkinCeuticals or Sesderma?

Reviewers note that SkinCeuticals has a high price point. The products on this page for Sesderma do not mention pricing information.

Which causes fewer breakouts, SkinCeuticals or Sesderma?

SkinCeuticals is a better fit for acne-prone skin, as the products on this page include multiple options with High and Superior fit levels for oily and acne-prone skin.

How many products from each brand contain fragrance?

SkinCeuticals has 34 products on this page with no fragrance and 3 with fragrance, while Sesderma has 1 product on this page with fragrance.

Which brand has been on the market longer and where was it founded?

Sesderma has been on the market slightly longer, having been founded in Spain in 1989, while SkinCeuticals was founded in the United States in 1994.

What are the key ingredients shared across the products of these brands?

SkinCeuticals and Sesderma do not share any key ingredients among the products on this page, as Sesderma features only Azelac RU Serum while SkinCeuticals includes ingredients like glycerin, hyaluronic acid, and vitamin C.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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