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SkinCeuticals vs Sesderma

Rated by Lovi 路 Unbiased, science-based skincare AI trained on real user outcomes 路 How the Fit score works

SkinCeuticals and Sesderma are distinguished skincare houses from America and Spain that offer thoughtful ranges of advanced serums, moisturizers, cleansers, and eye products. The American brand relies on essential ingredients like glycerin, hyaluronic acid, and dimethicone, suiting oily and acne-prone skin best with standout formulations such as C E Ferulic, Sheer Physical UV Defense SPF 50, and A.G.E. Advanced Eye. Meanwhile, the Spanish creator is beloved for meticulously engineered formulas featuring botanical extracts and active compounds that suit sensitive, hyperpigmented, and aging skin types, with the Azelac RU Serum standing out for acne-prone concerns. While both brands harness powerful ingredients to benefit the complexion, they differ in their foundational origins, targeted skin profiles, and specific active compositions.

SkinCeuticals is an American skincare brand founded in 1994 and owned by L'Or茅al since 2005.

loreal.comskinceuticals-za.compitchbook.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular SkinCeuticals and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular SkinCeuticals vs Sesderma products

SkinCeuticals vs Sesderma serums and treatments

Questions and answers

SkinCeuticals or Sesderma: which is better?

SkinCeuticals is the better choice for most shoppers on this page, as it offers a large selection of specialized products with High and Superior Lovi fit levels for skin types like acne-prone and combination skin. Sesderma only features one product on the page, Azelac RU Serum, which has a High fit for acne-prone skin and skin with dark spots.

What is the difference between SkinCeuticals and Sesderma?

SkinCeuticals is a US brand offering a large range of products on this page with High to Superior Lovi fits for acne-prone and combination skin, whereas Sesderma is a Spanish brand with only one serum listed on this page.

Which is more affordable, SkinCeuticals or Sesderma?

Reviews on the Lovi page note that SkinCeuticals has a high price point, but the page does not provide pricing or affordability details for Sesderma.

Which causes fewer breakouts, SkinCeuticals or Sesderma?

SkinCeuticals is a better fit for acne-prone skin on this page, as it offers multiple products with High or Superior fit levels for managing breakouts. Sesderma features only a single serum with a High fit for acne-prone skin.

Which brand has more products that list no fragrance, SkinCeuticals or Sesderma?

SkinCeuticals has significantly more products that list no fragrance than Sesderma, with 34 out of its 37 products being fragrance-free compared to none for Sesderma on this page.

Where and when were SkinCeuticals and Sesderma founded, and who currently owns them?

SkinCeuticals was founded in 1994 in the United States and has been owned by L'Or茅al since 2005. Sesderma was founded in 1989 in Spain and is owned by Grupo Sesderma.

How does the Lovi fit level for Azelac RU Serum compare between acne-prone skin and dry skin for Sesderma?

For Sesderma, the products on this page show that Azelac RU Serum has a High Lovi fit level for acne-prone skin, while it has a Low fit level for dry skin.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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