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SkinCeuticals vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

SkinCeuticals and Sesderma are esteemed skincare brands that offer advanced serums, nourishing moisturizers, gentle cleansers, and soothing eye products. The American brand is loved for its glycerin, hyaluronic acid, and dimethicone formulations that suit dry skin and dry sensitive skin best, while the Spanish brand is beloved for its meticulous engineering that suits sensitive, hyperpigmented, and aging skin types best. Both brands differ in their specific botanical extracts, active compounds, and restorative elements designed to target concerns like acne, dark spots, and mature skin.

SkinCeuticals is an American skincare brand founded in 1994 and owned by L'Oréal since 2005.

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Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular SkinCeuticals and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular SkinCeuticals vs Sesderma products

SkinCeuticals vs Sesderma serums and treatments

Questions and answers

SkinCeuticals or Sesderma: which is better?

SkinCeuticals is generally better because it offers a wide variety of high-performing products suited for multiple skin types, whereas Sesderma only features one product on this page. SkinCeuticals products on this page often help improve skin texture and hydration.

What is the difference between SkinCeuticals and Sesderma?

SkinCeuticals is a US brand founded in 1994 with a wide range of products on this page best fitting dry, dry sensitive, and oily skin, whereas Sesderma is a Spanish brand founded in 1989 with only one product listed here. SkinCeuticals offers many fragrance-free options across its catalog, while Sesderma's sole listed product contains fragrance.

Which is more affordable, SkinCeuticals or Sesderma?

The products on this page for SkinCeuticals are frequently noted by reviewers for having a high price point.

Which causes fewer breakouts, SkinCeuticals or Sesderma?

SkinCeuticals includes several serums and cleansers with High or Superior Lovi fit levels for acne-prone and oily skin, while Sesderma has only one serum on this page, which has a High fit level for acne-prone skin.

How many products from SkinCeuticals contain fragrance compared to Sesderma?

SkinCeuticals has 34 out of 37 products on this page with no fragrance, meaning 3 products contain it, while Sesderma has 1 out of 1 product on this page with fragrance.

When was each brand founded and where are their headquarters located?

SkinCeuticals was founded in the United States in 1994, while Sesderma was founded in Spain in 1989.

Which skin types are best suited for SkinCeuticals according to its brand-focused routines?

SkinCeuticals is best suited for dry skin, dry sensitive skin, and oily skin, according to its brand-focused routines.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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