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SkinCeuticals vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

SkinCeuticals and Sesderma are esteemed skincare brands that offer advanced serums, nourishing moisturizers, gentle cleansers, and soothing eye products. The American brand is loved for its glycerin, hyaluronic acid, and dimethicone formulations that suit dry skin and dry sensitive skin best, while the Spanish brand is beloved for its meticulous engineering that suits sensitive, hyperpigmented, and aging skin types best. Both brands differ in their specific botanical extracts, active compounds, and restorative elements designed to target concerns like acne, dark spots, and mature skin.

SkinCeuticals is an American skincare brand founded in 1994 and owned by L'Oréal since 2005.

loreal.comskinceuticals-za.compitchbook.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular SkinCeuticals and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular SkinCeuticals vs Sesderma products

SkinCeuticals vs Sesderma serums and treatments

Questions and answers

SkinCeuticals or Sesderma: which is better?

SkinCeuticals offers a much wider variety of products on this page across multiple skin types compared to Sesderma, which only lists one. The products on this page help improve skin texture and hydration.

What is the difference between SkinCeuticals and Sesderma?

SkinCeuticals is a much larger American brand founded in 1994 with an extensive range of thirty-seven products on this page, while Sesderma is a Spanish brand founded in 1989 represented by only one product here. SkinCeuticals fits dry, dry sensitive, and oily skin best, and the products on this page generally feature no fragrance.

Which is more affordable, SkinCeuticals or Sesderma?

Reviewers note that SkinCeuticals has a high price point. The products on this page for Sesderma do not provide enough pricing data to compare affordability.

Which causes fewer breakouts, SkinCeuticals or Sesderma?

SkinCeuticals fits acne-prone skin with high levels across multiple items on this page, whereas Sesderma includes only Azelac RU Serum which has a high fit there too.

When were SkinCeuticals and Sesderma founded, and where are they based?

SkinCeuticals was founded in the United States in 1994, while Sesderma was founded in Spain in 1989.

How many SkinCeuticals products list no fragrance compared to Sesderma?

Thirty-four of the thirty-seven SkinCeuticals products on this page list no fragrance, while zero of the one Sesderma products list no fragrance.

Which key ingredients are shared across SkinCeuticals products?

SkinCeuticals products share several key ingredients across the range, including glycerin, hyaluronic acid, dimethicone, glycolic acid, salicylic acid, vitamin C, ferulic acid, and aloe vera. Topical hyaluronic acid helps improve skin quality and signs of aging.

Dermatologic Therapy, 2022

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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