Topical use of dexpanthenol in skin disorders
Vitamin b5 panthenol, Panthenol · American Journal of Clinical Dermatology, 2002The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review
Aloe barbadensis leaf juice powder, Aloe barbadensis · Iranian Journal of Medical Sciences, 2019Efficacy of combined treatment with human adipose tissue stem cell-derived exosome-containing solution and microneedling for facial skin aging: A 12-week prospective, randomized, split-face study
Exosome cica · Journal of Cosmetic Dermatology, 2023Caffeine's mechanisms of action and its cosmetic use
Caffeine · Skin Pharmacology and Physiology, 2013Improvement of naturally aged skin with vitamin A (retinol)
Retinol · Archives of Dermatology, 2007Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo
Vitamin c derivatives · Experimental Dermatology, 2003Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin
Aha · Journal of Dermatological Science, 2017A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation
Ferulic acid · Journal of the American Academy of Dermatology, 2008Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial
Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin
Phloretin, Ferulic acid · Journal of Cosmetic Dermatology, 2008Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics
Collagen, Water-soluble collagen · Dermatology Practical & Conceptual, 2022Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin
Palmitoyl pentapeptide-4 · International Journal of Cosmetic Science, 2005Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Retinol · International Journal of Cosmetic Science, 2017Effects of menthol and cold on histamine-induced itch and skin reactions in man
Menthol · Neuroscience Letters, 1995Tea tree oil reduces histamine-induced skin inflammation
Tree · The British Journal of Dermatology, 2002Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing
Retinol · The British Journal of Dermatology, 2019Anti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression
Advanced peptide complex · International Journal of Molecular Sciences, 2019Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Chamomilla recutita flower extract, Chamomilla recutita extract · International Journal of Molecular Medicine, 2016Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract
Centella asiatica extract, Madecassoside · Indian Journal of Pharmaceutical Sciences, 2016Effect of fermentation time on the content of bioactive compounds with cosmetic and dermatological properties in Kombucha Yerba Mate extracts
Saccharomyces xylinum black tea ferment · Scientific Reports, 2021Use of Collagen in Cosmetic Products
Collagen, Water-soluble collagen · Current Issues in Molecular Biology, 2024Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations
Aloe barbadensis leaf juice powder, Aloe barbadensis leaf juice, Aloe barbadensis leaf extract · Clinical Pharmacology, 2018Urea: a comprehensive review of the clinical literature
Urea · Dermatology Online Journal, 2013Effect of Camellia japonica oil on human type I procollagen production and skin barrier function
Camellia japonica flower extract · Journal of Ethnopharmacology, 2007Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin
Ceramides · Scientific Reports, 2022Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin
Ceramide eop, Ceramide np · International Journal of Dermatology, 2008Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation
Ferulic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020Licochalcone A activates Nrf2 in vitro and contributes to licorice extract-induced lowered cutaneous oxidative stress in vivo
Glycyrrhiza glabra extract · Experimental Dermatology, 2015Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study
Retinyl palmitate · International Journal of Nanomedicine, 2021Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls
Camellia sinensis leaf extract · Experimental Dermatology, 2009Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin
Centella asiatica leaf extract · Experimental Dermatology, 2008The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study
Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy
Niacinamide · Journal of Cosmetic Dermatology, 2021The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial
Madecassoside · Journal of Alternative and Complementary Medicine, 2020Protective effects of a new phloretin derivative against UVB-induced damage in skin cell model and human volunteers
Phloretin · International Journal of Molecular Sciences, 2014Topical taurine bromamine, a new candidate in the treatment of moderate inflammatory acne vulgaris: a pilot study
Taurine · European Journal of Dermatology, 2008The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study
Hexapeptide · American Journal of Clinical Dermatology, 2013Protective effects of Camellia japonica flower extract against urban air pollutants
Camellia japonica flower extract · BMC Complementary and Alternative Medicine, 2019Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite as a novel cosmetic ingredient against skin aging
Bentonite · Carbohydrate Polymers, 2017Evaluation of Cosmetic and Dermatological Properties of Kombucha-Fermented Berry Leaf Extracts Considered to Be By-Products
Saccharomyces xylinum black tea ferment · Molecules, 2022Treatment of human skin with an extract of Fucus vesiculosus changes its thickness and mechanical properties
Algae extract · Journal of Cosmetic Science, 2002A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population
Salicylic acid, Bha beta hydroxy acid · BioMed Research International, 2020Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging
Niacinamide · Scientific Reports, 2024A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora
Vitamin b5 panthenol, Pantothenic acid, Panthenol · The Journal of Dermatological Treatment, 2017Development and photoprotective effect of a sunscreen containing the antioxidants Spirulina and dimethylmethoxy chromanol on sun-induced skin damage
Dimethylmethoxy chromanol · European Journal of Pharmaceutical Sciences, 2017Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study
Glycolic acid · Journal of Cosmetic Dermatology, 2019Safety and Toxicological Evaluation of a Novel, Standardized 3-O-Acetyl-11-keto-beta-Boswellic Acid (AKBA)-Enriched Boswellia serrata Extract (5-Loxin(R))
Boswellia serrata extract, Boswellia serrata gum · Toxicology Mechanisms and Methods, 2006Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation
Tocopheryl acetate · Urologia Internationalis, 2019Formulation and evaluation on human skin of a water-in-oil emulsion containing Muscat hamburg black grape seed extract
Grape seed oil · International Journal of Cosmetic Science, 2015Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration
Adenosine · International Journal of Cosmetic Science, 2018Hydrolyzed Collagen Induces an Anti-Inflammatory Response That Induces Proliferation of Skin Fibroblast and Keratinocytes
Collagen extract · Nutrients, 2022A randomized, single-blinded trial of a tripeptide/hexapeptide healing regimen following laser resurfacing of the face
Hexapeptide · Journal of Cosmetic Dermatology, 2017Effects of lecithin-based nanoemulsions on skin: Short-time cytotoxicity MTT and BrdU studies, skin penetration of surfactants and additives and the delivery of curcumin
Hydrogenated lecithin · International Journal of Pharmaceutics, 2020Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial
Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study
Vitamin c derivatives · Photochemistry and Photobiology, 2021The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study
Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019Evaluation of anti-acne properties of phloretin in vitro and in vivo
Phloretin · International Journal of Cosmetic Science, 2016High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin
Witch hazel · Phytochemistry, 2001Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy
Centella asiatica extract, Madecassoside, Centella asiatica leaf extract · Molecules, 2023A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Gluconolactone · The Australasian Journal of Dermatology, 1992Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin
Hexapeptide · Annals of Dermatology, 2019Efficacy of olive leaf extract-containing cream for facial rejuvenation: A pilot study
Olea europaea leaf extract olive leaf extract · Journal of Cosmetic Dermatology, 2020Taurine bromamine (TauBr)--its role in immunity and new perspectives for clinical use
Taurine · Journal of Biomedical Science, 2010Allergy to oxidized limonene and linalool is frequent in the U.K
Citrus aurantium dulcis peel oil · The British Journal of Dermatology, 2014Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study
Salicylic acid, Bha beta hydroxy acid · Journal of Cosmetic Dermatology, 2024Comparative Study of 35% Glycolic Acid, 20% Salicylic-10% Mandelic Acid, and Phytic Acid Combination Peels in the Treatment of Active Acne and Postacne Pigmentation
Phytic acid · Journal of Cutaneous and Aesthetic Surgery, 2019Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach
Zinc oxide · Journal of Controlled Release, 2025Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects
Vitamin e · Journal of Cosmetic Dermatology, 2020A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid
Ceramide np · Skin Pharmacology and Physiology, 2022Acid-base combination principles for preparation of anti-acne dissolving microneedles loaded with azelaic acid and matrine
Sophora angustifolia root extract, Sophora flavescens root extract · European Journal of Pharmaceutical Sciences, 2021Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications
Palmitoyl oligopeptide · Journal of Cosmetic Dermatology, 2015A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide
Salicylic acid, Bha beta hydroxy acid · Journal of Drugs in Dermatology, 2023Comparison of skin calming effects of cosmetic products containing 4-t-butylcyclohexanol or acetyl dipeptide-1 cetyl ester on capsaicin-induced facial stinging in volunteers with sensitive skin
Acetyl dipeptide-1 cetyl ester · Journal of the European Academy of Dermatology and Venereology, 2016Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial
Pantothenic acid · Journal of Cosmetic Dermatology, 2019Oxidized citrus oil (R-limonene): a frequent skin sensitizer in Europe
Citrus aurantium dulcis peel oil · Journal of the American Academy of Dermatology, 2002Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs
Vitamin e · Journal of Cosmetic Dermatology, 2022Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release
Oenothera biennis flower extract · Biomaterials Advances, 2022Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function
Propanediol · International Journal of Cosmetic Science, 2024Challenging the safety and efficacy of topically applied chlorogenic acid, apigenin, kaempferol, and naringenin by HET-CAM, HPLC-TBARS-EVSC, and laser Doppler flowmetry
Grapefruit fruit extract · Frontiers in Chemistry, 2024Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations
Vitamin e · Journal of Cosmetic Dermatology, 2022Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract
Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019New clinical approach in facial mild-moderate acne: Re-stabilization of skin microbiota balance with a topical biotechnological phytocomplex
Succinic acid · Journal of Cosmetic Dermatology, 2024The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study
Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris
Capryloyl salicylic acid, Hydroxyethylpiperazine ethane sulfonic acid, Citric acid · Journal of Cosmetic Dermatology, 2021Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison
Willow bark extract · Journal of Cosmetic Dermatology, 2019Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract
Willow bark extract · Planta Medica, 2019An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging
Willow bark extract · Journal of Cosmetic Dermatology, 2010A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris
Lauric acid · Dermatologic Therapy, 2020The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging
Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2023Administration of skin care regimens containing β-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study
Beta-glucan · Journal of Cosmetic Dermatology, 2021Assessment of Cosmetic and Dermatological Properties and Safety of Use of Model Skin Tonics with Kombucha-Fermented Red Berry Extracts
Saccharomyces xylinum black tea ferment · International Journal of Molecular Sciences, 2022Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement
Adenosine · Journal of Cosmetic Dermatology, 2019Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol
Sorbitol · Journal of Cosmetic Science, 2013Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders
3-o-ethyl ascorbic acid · Polymers, 2023Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment
Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial
Ferulic acid · The Journal of Dermatological Treatment, 2025Antiaging, Brightening, and Antioxidant Efficacy of Fermented Bilberry Extract (Vaccinium myrtillus): A Randomized, Double-Blind, Placebo-Controlled Trial
Vaccinium myrtillus fruit extract · Nutrients, 2024Development of grape seed extract based formulations by using non-invasive biophysical technique and its impact on skin aging
Grape seed oil · Pakistan Journal of Pharmaceutical Sciences, 2021Efficacy of octenidine dihydrochloride and 2-phenoxyethanol in the topical treatment of inflammatory acne
Phenoxyethanol · Acta Dermatovenerologica Alpina, Pannonica, Et Adriatica, 2008Gene expression profile of human follicle dermal papilla cells in response to Camellia japonica phytoplacenta extract
Camellia japonica flower extract · FEBS Open Bio, 2021Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025Safety assessment of a novel water-soluble extract of Boswellia serrata gum resin: acute toxicity, 90-day sub-chronic toxicity, Ames' bacterial reverse mutation, and in vivo micronucleus assays
Boswellia serrata extract, Boswellia serrata gum · Toxicology Mechanisms and Methods, 2022Comparison of topical purslane & topical 0.1% triamcinolone acetonide in the management of oral lichen planus - a double blinded clinical trial
Portulaca oleracea extract · BMC Oral Health, 2023Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores
Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007Influence of vitamin E acetate on stratum corneum hydration
Tocopheryl acetate · Arzneimittel-Forschung, 1998Anti-inflammatory and skin-hydrating properties of a dietary supplement and topical formulations containing oligomeric proanthocyanidins
Grape seed oil · Skin Pharmacology and Physiology, 2007Clinical study of Asian skin changes after application of a sunscreen formulation containing grape seed extract
Grape seed extract · Journal of Cosmetic Dermatology, 2022Synergistic action of a triple peptide complex on an essential extra-cellular matrix protein exhibits significant anti-aging benefits
Advanced peptide complex · Journal of Cosmetic Dermatology, 2010Semi-solid functionalized nanostructured lipid carriers loading thymol for skin disorders
Thymus vulgaris extract · International Journal of Pharmaceutics, 2024A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants
Dimethicone · Ostomy/wound Management, 2005A randomized controlled study to evaluate the depigmenting activity of L-ascorbic acid plus phytic acid-serum vs. placebo on solar lentigines
Phytic acid · Journal of Cosmetic Dermatology, 2011Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence
Zinc oxide · Biomedicines, 2025The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays
Propanediol · Molecules, 2021Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study
Vitamin b5 panthenol, Panthenol · Journal of Cosmetic Dermatology, 2025Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study
Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026A Randomized, Investigator-Blinded, Split-Face, Controlled Trial Evaluating the Efficacy and Satisfaction of a Topical Product Containing Blueberry Extract and Pro-Xylane Combined With Micro-Focused Ultrasound for Anti-aging
Blueberry extract, Proxylane · Journal of Cosmetic Dermatology, 2025Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects
Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024Effects of topical boswellic acid on photo and age-damaged skin: clinical, biophysical, and echographic evaluations in a double-blind, randomized, split-face study
Boswellia serrata extract, Boswellia serrata gum · Planta Medica, 2010Enhancing the Cosmetic Potential of Aloe Vera Gel by Kombucha-Mediated Fermentation: Phytochemical Analysis and Evaluation of Antioxidant, Anti-Aging and Moisturizing Properties
Saccharomyces xylinum black tea ferment · Molecules, 2025Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin
Vitamin e · Journal of Cosmetic Dermatology, 2024Functional properties and skin care effects of sodium trehalose sulfate
Trehalose · Skin Research and Technology, 2024Composition characterization and clinical efficacy study of a salmon egg extract
Salmon egg extract · International Journal of Cosmetic Science, 2013Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence
Adenosine · International Journal of Molecular Sciences, 2026Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy
Tocopheryl acetate · Scientific Reports, 2025Ethanolamines permeate slowly across human skin ex vivo, but cause severe skin irritation at low concentrations
Ethanolamine · Archives of Toxicology, 2019Histometric assessment of the age-related skin response to 2-hydroxy-5-octanoyl benzoic acid
Capryloyl salicylic acid · Skin Pharmacology and Applied Skin Physiology, 1998Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris
Capryloyl salicylic acid, Hydroxyethylpiperazine ethane sulfonic acid, Citric acid · Journal of Drugs in Dermatology, 2013Evaluation of additive effects of hydrolyzed jojoba (Simmondsia chinensis) esters and glycerol: a preliminary study
Jojoba esters · Journal of Cosmetic Dermatology, 2008Peptide-pro complex serum: Investigating effects on aged skin
Marine extracts · Journal of Cosmetic Dermatology, 2023Green Synthesis of Copper Oxide Nanoparticles using Cucumis Sativus (Cucumber) Extracts and their Bio-Physical and Biochemical Characterization for Cosmetic and Dermatologic Applications
Cucumis sativus fruit extract · Endocrine, Metabolic & Immune Disorders Drug Targets, 2021Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling
Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2022Anti-Aging Efficacy of Low-Molecular-Weight Polydeoxyribonucleotide Derived from Paeonia lactiflora
Sodium dna, Pdrn polydeoxyribonucleotide · International Journal of Molecular Sciences, 2025Polydeoxyribonucleotide-spermidine nanoparticles: Preparation, characterization, and verification of skin anti-aging efficacy
Sodium dna · International Journal of Biological Macromolecules, 2025Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial
Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021Efficacy of Topical Hydroxypinacolone Retinoate-Peptide Product Versus Fractional CO2 Laser in Facial Aging
Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2025Clinical Efficacy of a Flavo-Proxylane Topical Regimen Pre- and Post-ultrasound Procedure for Subjects Undergoing Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Therapy
Proxylane · Dermatology and Therapy, 2026Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin
Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2025The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial
Bentonite · Journal of Cosmetic Dermatology, 2025Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters
Gluconolactone · Skin Research and Technology, 2023Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial
Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026The effect of a serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies
Laminaria digitata extract · International Journal of Cosmetic Science, 2026The Application of a Formulation Containing Hydroxypropyl Tetrahydropyrantriol and Niacinamide to Augment Anti-aging Benefits in a Double-blind, Randomized Nonablative Laser Treatment Study
Proxylane · The Journal of Clinical and Aesthetic Dermatology, 2025Clinical Evaluation of a Soap-Free Cleansing Lotion Containing Sodium Cocoyl Apple Amino Acids for Effective Impurity Removal and Skin Barrier Preservation in Healthy Adults With Diverse Skin Types
Cetyl alcohol · Cureus, 2025Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking
Palmitoyl oligopeptide · International Journal of Cosmetic Science, 2026