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SkinCeuticals vs Sesderma

Rated by Lovi 路 Unbiased, science-based skincare AI trained on real user outcomes 路 How the Fit score works

SkinCeuticals and Sesderma are esteemed skincare brands founded respectively in the United States and Spain. The American brand is loved for its thoughtful formulations of serums, moisturizers, cleansers, and eye products relying on glycerin, hyaluronic acid, and dimethicone, while the Spanish brand is beloved for its advanced serums and meticulously engineered formulas. Both labels suit distinct needs, with the former catering best to acne-prone and oily skin and the latter serving sensitive, hyperpigmented, and aging skin types best. They differ primarily in their origin, founding eras, and the specific functional capacities of their standout offerings.

SkinCeuticals is an American skincare brand founded in 1994 and owned by L'Or茅al since 2005.

loreal.comskinceuticals-za.compitchbook.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular SkinCeuticals and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular SkinCeuticals vs Sesderma products

SkinCeuticals vs Sesderma serums and treatments

Questions and answers

SkinCeuticals or Sesderma: which is better?

SkinCeuticals is generally better for a wider variety of skincare needs, as the products on this page offer extensive options for acne-prone, oily, and dry sensitive skin. Sesderma has a much more limited lineup on this page.

What is the difference between SkinCeuticals and Sesderma?

SkinCeuticals is a US brand founded in 1994, offering a wide range of products that are mostly fragrance-free and well-suited for acne-prone, oily, and dry sensitive skin. In contrast, Sesderma is a Spanish brand founded in 1989 with a smaller product selection on this page, and its featured item contains fragrance.

Which is more affordable, SkinCeuticals or Sesderma?

Reviewers frequently note that the products on this page by SkinCeuticals have a high price point.

Which causes fewer breakouts, SkinCeuticals or Sesderma?

SkinCeuticals has a High fit for acne-prone skin across many products on this page, whereas Sesderma is represented by only one product with a High fit for acne-prone skin.

Which brand has more products that list no fragrance?

SkinCeuticals has more products that list no fragrance, with 34 out of 37 products on this page being fragrance-free compared to none for Sesderma.

Where and when were SkinCeuticals and Sesderma founded?

SkinCeuticals was founded in the United States in 1994, and Sesderma was founded in Spain in 1989.

Which SkinCeuticals products are rated as Superior for dry skin?

SkinCeuticals products on this page rated as Superior for dry skin are Triple Lipid Restore 2:4:2, Retexturing Activator, and Hydrating B5 Masque.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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