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CeraVe vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

CeraVe and Sesderma are trusted skincare brands that offer reliable options for daily routines. The American brand is widely loved for its thoughtful range of moisturizers, cleansers, serums, sunscreens, and more, all formulated with skin-loving ingredients like hyaluronic acid and glycerin, while the Spanish brand is beloved for its advanced serums and meticulously engineered formulas. The former suits acne-prone skin and combination skin best due to their supportive formulations, whereas the latter suits sensitive, hyperpigmented, and aging skin types best. Both differ primarily in their founding heritage and targeted product philosophies, with the American brand featuring essentials like the Foaming Facial Cleanser, Skin Renewing Nightly Exfoliating Treatment, and Skin Renewing Night Cream, and the Spanish brand featuring standout solutions like the Azelac RU Serum.

CeraVe is an American skincare brand founded in 2005 and owned by L'Oréal since 2017.

en.wikipedia.orghappi.comloreal-finance.comcerave.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular CeraVe and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular CeraVe vs Sesderma products

CeraVe vs Sesderma serums and treatments

Questions and answers

CeraVe or Sesderma: which is better?

CeraVe offers a much larger selection of fragrance-free products on this page that achieve a High or Superior Lovi fit across acne-prone, combination, and mature skin types. In comparison, Sesderma only lists a single serum on this page, which contains fragrance.

What is the difference between CeraVe and Sesderma?

CeraVe offers a broad range of fragrance-free products on this page with High to Superior Lovi fit levels for acne-prone, combination, and mature skin, whereas Sesderma features a single serum that contains fragrance.

Which is more affordable, CeraVe or Sesderma?

The products on this page do not provide pricing information to determine which brand is more affordable.

Which causes fewer breakouts, CeraVe or Sesderma?

CeraVe helps provide many lightweight moisturizers and cleansers that are well-suited for acne-prone skin, whereas Sesderma features only one serum on this page without a dedicated breakout range.

When were CeraVe and Sesderma founded and in which countries?

CeraVe was founded in 2005 in the United States, while Sesderma was founded in 1989 in Spain.

Do CeraVe products contain fragrance compared to Sesderma's Azelac RU Serum?

Every product on the CeraVe page lists no fragrance in its ingredients, whereas Sesderma's Azelac RU Serum contains fragrance.

Which brand has more products listed on the comparison page for dry and acne-prone skin?

CeraVe has significantly more products listed on the comparison page than Sesderma, which only features one product overall. CeraVe offers multiple options specifically tailored for both dry skin and acne-prone skin.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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