🇺🇸United States

CeraVe vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

CeraVe and Sesderma are trusted skincare brands that offer reliable daily routines and advanced treatments, respectively. The American brand, founded in 2005, is known for dependable moisturizers, gentle cleansers, targeted serums, and protective sunscreens enriched with hyaluronic acid and glycerin, suiting mature and dry skin best. Meanwhile, the Spanish brand, founded in 1989, is beloved for advanced serums and meticulously engineered formulas that suit sensitive, hyperpigmented, and aging skin. While both deliver proven results through active compounds and botanical extracts, the former relies on barrier-supporting ingredients like glycerin, whereas the latter specializes in synergistic treatments like the Azelac RU Serum.

CeraVe is an American skincare brand founded in 2005 and owned by L'Oréal since 2017.

en.wikipedia.orghappi.comloreal-finance.comcerave.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular CeraVe and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular CeraVe vs Sesderma products

CeraVe vs Sesderma serums and treatments

Questions and answers

CeraVe or Sesderma: which is better?

CeraVe has a High fit for mature skin, dry skin, and acne-prone skin, whereas Sesderma has only one product on this page with a High fit for acne-prone skin and skin with dark spots. Additionally, the products on this page from CeraVe list no fragrance, while Sesderma's serum contains fragrance.

What is the difference between CeraVe and Sesderma?

CeraVe offers a large selection of fragrance-free cleansers, moisturizers, and serums with a Superior or High Lovi fit for mature, dry, and acne-prone skin, while Sesderma features just one serum on this page that contains fragrance. CeraVe products on this page help provide barrier repair with ingredients like ceramides and hyaluronic acid.

Dermatologic Therapy, 2022

Which is more affordable, CeraVe or Sesderma?

This comparison page does not provide pricing or affordability information for either CeraVe or Sesderma.

Which causes fewer breakouts, CeraVe or Sesderma?

CeraVe helps provide many fragrance-free products on this page, whereas the Azelac RU Serum by Sesderma contains fragrance.

Between CeraVe and Sesderma, which brand was founded earlier and in which countries?

Sesderma was founded earlier in Spain in 1989, whereas CeraVe was founded later in the United States in 2005.

How do the fragrance options compare between CeraVe and Sesderma products listed on the page?

Every CeraVe product on this page lists no fragrance in its ingredients, whereas the single Sesderma product listed includes fragrance. Reviewers note that CeraVe's fragrance-free moisturizers help keep skin comfortable.

Which brand offers a wider range of product categories like cleansers, moisturizers, and serums?

CeraVe offers a wider range of products on this page, including multiple cleansers, moisturizers, and serums. In comparison, Sesderma only features a single serum.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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